Results 21 to 30 of about 560,464 (384)

Identifying Regulatory Posttranslational Modifications of PD-L1: A Focus on Monoubiquitinaton

open access: yesNeoplasia: An International Journal for Oncology Research, 2017
A set of high-affinity, high-specificity posttranslational modification (PTM) enrichment tools was developed to generate an unbiased snapshot of four key PTM profiles (tyrosine phosphorylation, acetylation, ubiquitination, and SUMOylation 2/3) for the ...
Henrick Horita   +3 more
doaj   +1 more source

Cfap91-Dependent Stability of the RS2 and RS3 Base Proteins and Adjacent Inner Dynein Arms in Tetrahymena Cilia

open access: yesCells, 2022
Motile cilia and eukaryotic flagella are specific cell protrusions that are conserved from protists to humans. They are supported by a skeleton composed of uniquely organized microtubules—nine peripheral doublets and two central singlets (9 × 2 + 2 ...
Marta Bicka   +6 more
doaj   +1 more source

Models of dynamic extraction of lipid tethers from cell membranes [PDF]

open access: yes, 2010
When a ligand that is bound to an integral membrane receptor is pulled, the membrane and the underlying cytoskeleton can deform before either the membrane delaminates from the cytoskeleton or the ligand detaches from the receptor.
Cuvelier D   +4 more
core   +1 more source

Synthesis of spectrin in avian erythroid cells: association of nascent polypeptide chains with the cytoskeleton [PDF]

open access: yes, 1983
The site of synthesis of spectrin was investigated in erythroid cells from 10-day chicken embryos. After various periods of [35S]methionine incorporation the cells were lysed in a Triton X-100 (TX-100)-containing buffer and were separated into a TX-100 ...
Blikstad, Ingrid, Lazarides, Elias
core   +2 more sources

cis-acting sequences and trans-acting factors in the localization of mRNA for mitochondrial ribosomal proteins [PDF]

open access: yes, 2008
mRNA localization is a conserved post-transcriptional process crucial for a variety of systems. Although several mechanisms have been identified, emerging evidence suggests that most transcripts reach the protein functional site by moving along ...
AMORESANO, ANGELA   +5 more
core   +1 more source

Mechanical tumor microenvironment and transduction: cytoskeleton mediates cancer cell invasion and metastasis

open access: yesInternational Journal on Biological Sciences, 2020
Metastasis is a complicated, multistep process that is responsible for over 90% of cancer-related death. Metastatic disease or the movement of cancer cells from one site to another requires dramatic remodeling of the cytoskeleton.
Xingchen Li, Jianliu Wang
semanticscholar   +1 more source

The Actin Cytoskeleton as an Active Adaptive Material.

open access: yesAnnual Review of Condensed Matter Physics, 2020
Actin is the main protein used by biological cells to adapt their structure and mechanics to their needs. Cellular adaptation is made possible by molecular processes that strongly depend on mechanics.
Shiladitya Banerjee   +2 more
semanticscholar   +1 more source

Regulation of Microtubule Nucleation in Mouse Bone Marrow-Derived Mast Cells by Protein Tyrosine Phosphatase SHP-1

open access: yesCells, 2019
The antigen-mediated activation of mast cells initiates signaling events leading to their degranulation, to the release of inflammatory mediators, and to the synthesis of cytokines and chemokines.
Anastasiya Klebanovych   +8 more
doaj   +1 more source

Modelling host-Trypanosoma brucei gambiense interactions in vitro using human induced pluripotent stem cell-derived cortical brain organoids [version 2; peer review: 2 approved]

open access: yesF1000Research, 2023
Background: Sleeping sickness is caused by the extracellular parasite Trypanosoma brucei and is associated with neuroinflammation and neuropsychiatric disorders, including disruption of sleep/wake patterns, and is now recognised as a circadian disorder ...
Juan F. Quintana   +4 more
doaj   +1 more source

The evolution of the cytoskeleton [PDF]

open access: yesJournal of Cell Biology, 2011
The cytoskeleton is a system of intracellular filaments crucial for cell shape, division, and function in all three domains of life. The simple cytoskeletons of prokaryotes show surprising plasticity in composition, with none of the core filament-forming proteins conserved in all lineages.
Wickstead, B, Gull, K
openaire   +2 more sources

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