Results 101 to 110 of about 602,582 (313)

Cytotoxic Activity of Achillea coarctata Poir. Extract

, 2017
Achillea L. (Asteraceae) is a traditional medicinal herb which contains different phenol and flavonoid compounds that are responsible for Achillea pharmacological effects. Turkey is one of the most important centers of diversity for the genus Achillea in
Silahtarlıoğlu, Nurcan, ALBAYRAK, Sevil, Sevil Albayrak, Nurcan Silahtarlıoğlu   +3 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Differential Contribution of Fas- and Perforin-Mediated Mechanisms to the Cell-Mediated Cytotoxic Activity of Naive and In Vivo-Primed Intestinal Intraepithelial Lymphocytes

, 2000
Intestinal intraepithelial lymphocytes (IELs) are known to exert strong constitutive cytotoxic activity. In the present study we compared the Ag-specific cytotoxic activity and the effector mechanisms involved in non-Ag-primed, naive and in in vivo ...
Müller, Stefan, Thomas Brunner, Christoph Mueller, Mueller, Christoph, Stefan Müller, Kägi, David, David Kägi, Brunner, Thomas, Nadia Corazza, Corazza, Nadia   +9 more
core   +1 more source

Rapid synthesis of highly monodisperse AgSbS2 nanocrystals: unveiling multifaceted activities in cancer therapy, antibacterial strategies, and antioxidant defense

Beilstein Journal of Nanotechnology
Nanocrystals (NCs) of silver antimony sulfide (AgSbS2) in the cubic phase were successfully synthesized using the hot-injection method. This study is the first to investigate the cytotoxic effects of these NCs on human breast adenocarcinoma (MCF-7 ...
Funda Ulusu, Adem Sarilmaz, Yakup Ulusu, Faruk Ozel, Mahmut Kus   +4 more
doaj   +1 more source

Cytotoxic Activity of Alpinumisoflavone from Erythrina poeppigiana (Leguminosae) Against Colon Cancer (WiDr), Cervical Cancer (Hela), and Hepatoma Cancer (HepG2) Cells

Hayati Journal of Biosciences, 2019
Cancer is the second cause of death after cardiovascular diseases in the world. Anticancer prevention used can cause undesirable things. Flavonoids are secondary metabolites derived from natural products that are useful for anticancer treatment.
Tati Herlina, Nayla Haraswati, Riza Apriani, Vicki Nishinarizki, Shabarni Gaffar, Unang Supratman   +5 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Cytotoxic activity of crude extracts from Astragalus chrysochlorus (Leguminosae)

, 2007
In this study, cytotoxic activity of Astragalus chrysochlorus crude extracts was investigated Hexane, chloroform, ethylacetate, 80% ethanol and water extracts prepared from roots and stems of Astragalus chrysochlorus were tested for cytotoxic activity on
Cakir, O., A. Karagöz, N. Turgut-Kara, R. Demirgan, Ş. Arı, Karagoz, A., Turgut-Kara, N., Ö. Çakır, Ari, S., Demirgan, R.   +9 more
core   +1 more source

Conditional immortalization of human B cells by CD40 ligation [PDF]

, 2008
It is generally assumed that human differentiated cells have a limited life-span and proliferation capacity in vivo, and that genetic modifications are a prerequisite for their immortalization in vitro.
Mayr, C., Caroline Zentz, Reinhard Zeidler, Hammerschmidt, W., Wolfgang Hammerschmidt, Wiesner, Martina, Wimmer, Rainer, Wiesner, M., Christine Mayr, Hammerschmidt, Wolfgang, Zentz Caroline, Zentz, C., Moosmann, A., Zeidler, Reinhard, Wiesner Martina, Moosmann Andreas, Andreas Moosmann, Mayr Christine, Wimmer, R., Wimmer Rainer, Zentz, Caroline, Hammerschmidt Wolfgang, Mayr, Christine, Martina Wiesner, Moosmann, Andreas, Rainer Wimmer, Zeidler Reinhard, Zeidler, R.   +27 more
core   +1 more source

Cytotoxic Activity of Cycloartane Triterpenoids from

Natural Product Communications, 2009
The cytotoxicity of three cycloartane triterpenoids, 9, 19-cycloart-7β, 24R, 25- triol-1-en-3-one (1), 9, 19-cycloart-7β, 24R, 25-triol-1-en-3-one 25-O-β-D-glucopynanoside (2), and 25-O-β-D-arabinopyranosyl-(1→4)- β-D-glucopyranosyl-9, 19-cycloart-7β ...
Dan Wang, Zhongjun Ma
doaj   +1 more source

Thioglycollate-elicited murine macrophages are cytotoxic to Mycoplasma arginini-infected YAC-1 tumor cells

Brazilian Journal of Medical and Biological Research, 1998
Macrophages are important components of natural immunity involved in inhibition of tumor growth and destruction of tumor cells. It is known that these cells can be activated for tumoricidal activity by lymphokines and bacterial products.
F. Ribeiro-Dias, M. Russo, F.R.F. Nascimento, J.A.M. Barbuto, J. Timenetsky, S. Jancar   +5 more
doaj   +1 more source