Results 311 to 320 of about 11,083,244 (410)

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source

Cytotoxic Activity of Chemical Constituents of <i>Clerodendrum glabrum</i> and <i>Combretum nelsonii</i> Root Extracts Against Selected Cancer Cell Lines. [PDF]

Plants (Basel)
Mabunda KV, Kemboi D, Famuyide IM, McGaw LJ, Mokgalaka-Fleischmann NS, Tembu VJ.   +5 more
europepmc   +1 more source

Antioxidant, Antimicrobial and Cytotoxic Activities of Alcoholic Leaves Extracts of Spatholobus parviflorus (Roxb.Ex Dc.) Kuntze

, 2018
E. J. Jesy, Beena Jose
openalex   +1 more source

Bioinspired Bromination Enables Extensible, Strain‐Stiffening Resilin Peptide Scaffolds with Tunable Degradation

Advanced Functional Materials, EarlyView.
Bioinspired bromination of a resilin‐derived peptide enables the fabrication of electrospun nanofibrous scaffolds that uniquely combine strain‐stiffening elasticity, proteolytic stability, and antioxidant functionality. These brominated peptide–gelatin hybrids mimic the extensibility of natural elastomers, demonstrating tunable mechanical resilience ...
Elisa Marelli, Lorenzo Sori, Chiara Russo, Claudia Pigliacelli, Lorenza Draghi, Monica Soncini, Pierangelo Metrangolo   +6 more
wiley   +1 more source

Colombian cyanobacteria with cytotoxic activity in cancer cell lines. [PDF]

Heliyon
Darwich-Cedeño MT, Montenegro-Ruiz LC, Reis M, Vasconcelos V.   +3 more
europepmc   +1 more source

Synthesis and characterization of juglone-derived Cu(II), Mn(II) and Zn(II) complexes and investigation of their cytotoxic activities against lung and colon cancer cells

Mustafa Öztatlıcı, Turan Birimoğlu, Semih Güler, Rukiye Betül Çolaksel, Mehmet Sönmez   +4 more
openalex   +1 more source

Functional differentiation of human cytotoxic T lymphocytes in the presence of FK 506 and CyA [PDF]

, 1990
Bach, FH, Duquesnoy, RJ, Eiras, G, Fung, JJ, Starzl, T, Todo, S, Zeevi, A   +6 more
core  

4D Mapping of ZIF Biocomposites for High Protein Loading and Tunable Release Profiles

Advanced Functional Materials, EarlyView.
Systematic four‐dimensional mapping of zeolitic imidazolate framework biocomposites reveals how precursor ratios, total concentration, and washing define crystalline phase, protein loading, and release kinetics. This comprehensive study identifies conditions yielding record loading (∼85%) and precise phase–property correlations.
Michael R. Hafner, Francesco Carraro, Behnaz Abbasgholi‐NA, Simone Dal Zilio, Max Schmallegger, Helmar Wiltsche, Lingcong Ge, Michael R. Reithofer, Efwita Astria, Laura Villanova, Heinz Amenitsch, Christian Doonan, Paolo Falcaro   +12 more
wiley   +1 more source

Evaluation of the Cytotoxic Activity of Nanostructured Lipid Carrier Systems for Fatty Acid Amides and Silk Fibroins in Breast Cancer Cell Lines. [PDF]

Molecules
Borges SDS, Miranda SEM, Marinho VHS, Barros ALB, Yoshioka S, Hage-Melim LIDS, Silva ACJ, Ferreira IM, Oliveira AEMFM.   +8 more
europepmc   +1 more source

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

Advanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee, Sojin Kim, Myeongeun Lee, Kyoungsuk Jin, Jimin Park   +4 more
wiley   +1 more source