These findings elucidate the innovative role of HIC1 as a transcriptional activator in GC, driving the initiation of pyroptosis and enhancing CD8+ T cell infiltration, which has certain novelty and creative significance. Collectively, targeting HIC1 can present an appealing immunotherapeutic strategy to improve outcomes in GC patients.
Mengjie Kang+4 more
wiley +1 more source
Cytotoxic T lymphocyte response to minor H-42a alloantigen in H-42b mice: clonal inactivation of the precursor cytotoxic T lymphocytes by veto-like spleen cells that express the H-42a antigen. [PDF]
Hiromichi Ishikawa+4 more
openalex +1 more source
Capacity of different cell types to stimulate cytotoxic T lymphocyte precursor cells in the presence of interleukin 2 [PDF]
Plastic-adherent cells enriched for dendritic cells (AC) were found to be among the most potent stimulator cells for the activation of cytotoxic T lymphocytes (CTL) in vitro in the presence of interleukin 2 (IL 2) and a constant second set of allogeneic ...
Dröge, W.+6 more
core
LincNEAT1 Encoded‐NEAT1‐31 micropeptide directly binds with Aurora‐A and enhanced AKT pathways to pormotes phagocytosis against multi cancer cells. Abstract Macrophages play vital roles in innate and adaptive immunity, and their essential functions are mediated by phagocytosis and antigen presentation.
Jie Li+8 more
wiley +1 more source
Murine cytotoxic T lymphocyte recognition of individual influenza virus proteins. High frequency of nonresponder MHC class I alleles. [PDF]
Jack R. Bennink, Jonathan W. Yewdell
openalex +1 more source
Isolation Techniques of Micro/Nano‐Scaled Species for Biomedical Applications
Separating micro/nano‐scale bioparticles from samples is essential for disease diagnosis, prevention, and monitoring. Therefore, a comprehensive overview of the latest advanced separation technologies is provided, and characteristics and limitations based on six key performance parameters, including purity, recovery rate, throughput, resolution, size ...
Qing Lu, Zhinan Zhang, Xianting Ding
wiley +1 more source
Recent clinical isolates of cytomegalovirus suppress human cytomegalovirus-specific human leukocyte antigen-restricted cytotoxic T-lymphocyte activity [PDF]
Rachel Schrier, Michael B. A. Oldstone
openalex +1 more source
Clonal expansion of CD4(+) cytotoxic T lymphocytes in patients with IgG4-related disease.
H. Mattoo+13 more
semanticscholar +1 more source
Activation of HTR2B suppresses osteosarcoma progression through the STAT1‐NLRP3 inflammasome pathway and promotes OASL1+ Macrophage production to enhance anti‐tumor immunity. Abstract Osteosarcoma is a primary malignant bone tumor originating from mesenchymal tissue, and associated with poor prognosis.
Zhen Huang+7 more
wiley +1 more source