Results 211 to 220 of about 937,918 (334)

Sacituzumab govitecan as a therapeutic breakthrough in the treatment of triple-negative breast cancer: a systematic review of clinical trials. [PDF]

Front Immunol
Piekarz J, Picheta N, Pobideł J, Szklener K, Skórzewska M.   +4 more
europepmc   +1 more source

The in vivo effect of hepatotrophic factors ALR, HGF, and IGF-II on natural killer cell functions [PDF]

, 1997
Azzarone, A, Deleo, A, Francavilla, A, Hagiya, M, Iacobellis, A, Polimeno, L, Starzl, TE, Vujanovic, N, Whiteside, T   +8 more
core  

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Successful Therapy with Obinutuzumab in a Toddler with Primary Multidrug-Resistant Nephrotic Syndrome. [PDF]

J Clin Med
Drozynska-Duklas M, Zagozdzon I, Chudzik I, Balasz-Chmielewska I, Kranz A, Zurowska A.   +5 more
europepmc   +1 more source

Released Granulocytic Elastase [PDF]

, 1985
Duswald, Karl-Heimo, Fritz, Hans, Jochum, Marianne, Schramm, Wolfgang   +3 more
core  

Long-term mixed chimerism after immunologic conditioning and MHC-mismatched stem-cell transplantation is dependent on NK-cell tolerance.

Blood, 2005
Geert Westerhuis, Wendy G E Maas, R. Willemze, R. Toes, W. Fibbe   +4 more
semanticscholar   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

B7-H3/CD276: Novel Immune Checkpoint and Jack of All Trades. [PDF]

Immunotargets Ther
Larkin B, Nishizaki D, Miyashita H, Lee S, Nikanjam M, Eskander RN, Jensen TJ, Pabla S, Conroy JM, DePietro P, Sicklick JK, Kurzrock R, Kato S.   +12 more
europepmc   +1 more source

Correlation of NK Cell Activation and Inhibition Markers with NK Cytoxicity Among Women Experiencing Immunologic Implantation Failure After In Vitro Fertilization and Embryo Transfer

Journal of Assisted Reproduction and Genetics, 2003
C. Coulam, R. Roussev
semanticscholar   +1 more source

Cancer Cell‐Intrinsic Cholesterol Induces Lipid‐Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression

Advanced Science, EarlyView.
Cancer cell‐intrinsic cholesterol promotes the S‐palmitoylation of SP1, increasing its nuclear translocation and driving the transcription and secretion of MDK, which in turn facilitates the differentiation of macrophages into a lipid‐associated phenotype.
Shirong Peng, Weilong Lin, Zean Li, Ruilin Zhuang, Shengmeng Peng, Bingheng Li, Bingliang Chen, Yong Luo, Yuan Ou, Wei Zhuang, Tao Du, Kaiwen Li, Hai Huang   +12 more
wiley   +1 more source