Results 241 to 250 of about 906,600 (363)
GD2-CAR NK-92 cell activity against neuroblastoma cells is insusceptible to TIGIT knockout. [PDF]
Jünemann W+6 more
europepmc +1 more source
Immunodeficiency Diseases and Tumor Immunobiology [PDF]
Abramoff, Peter A., Duquesnoy, Rene J.
core +1 more source
Immunologic response to cryoablation of breast cancer
M. Sabel+5 more
semanticscholar +1 more source
The tumor microenvironment‐responsive nanoagonists are developed using an organic–inorganic copolymer composed of the polymer (PC6AB) and manganous phosphate ionic oligomers (MnP). PC6AB with membranolytic activity selectively interacts with tumor cell membranes to induce immunogenic cell death, while MnP activates the STING pathway in immune cells ...
Shiming Zhang+14 more
wiley +1 more source
Plasticity of tumor cell immunogenicity: is it druggable? [PDF]
Dranoff G.
europepmc +1 more source
MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer
This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang+9 more
wiley +1 more source
Oral squamous cell carcinoma cells exhibit upregulated expression of GSDMD upon exposure to low‐dose cisplatin chemotherapy, which subsequently interacts with MMP14 through its N‐terminal domain, activating the epithelial‒mesenchymal transition (EMT) process and promoting the lymph node metastasis of oral squamous cell carcinoma.
Zixian Huang+9 more
wiley +1 more source
Exploring T-cell bispecific antibodies in gynecologic malignancy. [PDF]
O'Brien E, Mayer CM, Arend RC.
europepmc +1 more source
Pinosylvin Inhibits Inflammatory and Osteoclastogenesis via NLRP3 Inflammasome
Pinosylvin blocks LPS and RANKL induced NEK7/NLRP3 interaction, inhibiting NLRP3 inflammasome oligomerization and assembly, reducing IL‐1β maturation and GSDMD cleavage, and improving the inflammatory microenvironment and abnormal osteoclastogenesis. Abstract Pro‐inflammatory cytokines such as TNF, IL‐1, and IL‐6 trigger aberrant osteoclastogenesis and
Wei Zhang+13 more
wiley +1 more source