Results 281 to 290 of about 906,600 (363)

Obinutuzumab for treatment of membranous nephropathy in patients positive and negative for the phospholipase A₂ receptor antibody: case reports. [PDF]

Front Immunol
Wang J, Wu W, Wu H.
europepmc   +1 more source

Nanofabricated Bacterial Cell Walls with Intrinsic Peroxidase‐Mimicking and Sonodynamic Activities for Cancer Combination Treatment

Advanced Science, EarlyView.
Bacterial cell walls (CWs) extracted from Porphyromonas gingivalis are nanofabricated to form the CW vesicles (CWV), which have intrinsic peroxidase‐mimicking and sonodynamic activities due to the presence of µ‐oxo bisheme and meanwhile retain a large amount of lipopolysaccharide.
Meng Yang, Yang Meng, Junling Li, Liya Bai, Yuanyuan Cheng, Yuanyuan Liu, Mingxin Cao, Xiaoying Yang, Yinsong Wang, Yang Liu   +9 more
wiley   +1 more source

Amplifying Anti‐Tumor Immune Responses via Mitochondria‐Targeting Near‐Infrared Photodynamic Therapy

Advanced Science, EarlyView.
Interfacial Nd3+‐triplet energy transfer enables direct activation of molecular triplets under near‐infrared (NIR) irradiation for reactive oxygen species (ROS) generation. Photodynamic therapy (PDT) exaggerates hypoxia, which initiates subsequent hypoxia‐activated chemotherapy.
Cheng‐Ao Li, Junjie Nan, Qingxuan Ye, Bingzhu Zheng, Xiaomeng Dai, Jingya Li, Feng Wang, Huimin Ma, Yu Cheng, Jian Ruan, Weijia Fang, Peng Zhao, Renren Deng, Dong Cen   +13 more
wiley   +1 more source

Expanding role of antibodies in kidney transplantation. [PDF]

World J Transplant
Abbas K, Mubarak M.
europepmc   +1 more source

Pyroptosis‐Inducing Platinum(IV) Prodrugs via GSDME Pathway for Chemoimmunotherapy and Metastasis Inhibition in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Three PtIV prodrugs MRP, DRP, and HRP are designed to induce pyroptosis in low GSDME‐expressing tumor cells via the Caspase‐3/GSDME pathway. By relaxing chromatin and reactivating GSDME, HRP can effectively induce pyroptosis, enhance pro‐inflammatory cytokine production, and exhibit potent antitumor effects.
Xinda Yang, Chuansheng Xu, Youliang Zeng, Chunhui Wang, Yan Gao, Jie Ding, Sirui Chen, Yuheng Pan, Xin Zhang, Zongwan Mao, Shuo Shi   +10 more
wiley   +1 more source

Expression of the TIGIT axis and the CD39/CD73 purinergic pathway in bone metastasis-derived immune cells. [PDF]

Cancer Immunol Immunother
Brauneck E, Leonhardt LG, Assemissen AM, Wahid Y, Kruppa M, Kruppa N, Krüger J, Menzel S, Koch-Nolte F, Kylies J, Weisel K, Bokemeyer C, Wellbrock J, Fiedler W, Viezens L, Brauneck F.   +15 more
europepmc   +1 more source

Enhancing Chemotherapy‐Related Immune Responses via Bioorthogonal Metabolic Engineering‐Driven Tumor Exosomes Elimination

Advanced Science, EarlyView.
In this work, a novel strategy named bioorthogonal reaction‐driven exosome elimination (Biordee) strategy was developed to inhibit chemotherapy‐associated breast cancer metastasis and enhance the immune response. Biordee possessed the capacity of in‐situ editing tumor‐derived exosomes (TExo) with IgG Fc and promoted macrophage phagocytosis of ...
Wentao Zhang, Tianyi Yang, Tian Jin, Tianyi Zhu, Fang Hao, Miao Fan, Yanrong Zhang   +6 more
wiley   +1 more source

High tumor CD161 expression predicts a survival advantage and marks a Th1-skewed microenvironment. [PDF]

Front Immunol
Burns BA, Chandra M, Konduri V, Decker WK.   +3 more
europepmc   +1 more source

Trypstatin as a Novel TMPRSS2 Inhibitor with Broad‐Spectrum Efficacy against Corona and Influenza Viruses

Advanced Science, EarlyView.
Trypstatin, a 61‐amino acid Kunitz‐type protease inhibitor derived from human Bikunin, potently inhibits TMPRSS2 and related proteases. It blocks spike‐ and hemagglutinin‐mediated entry of multiple respiratory viruses in vitro reduces SARS‐CoV‐2 replication in human airway cultures, and lowers viral load and symptoms in infected hamsters, demonstrating
Jan Lawrenz, Lukas Wettstein, Armando Rodríguez Alfonso, Rayhane Nchioua, Pascal von Maltitz, Dan Pascal Jean Albers, Fabian Zech, Julie Vandeput, Lieve Naesens, Giorgio Fois, Veronika Neubauer, Nico Preising, Emilia Schmierer, Yasser Almeida‐Hernandez, Moritz Petersen, Ludger Ständker, Sebastian Wiese, Peter Braubach, Manfred Frick, Eberhard Barth, Daniel Sauter, Frank Kirchhoff, Elsa Sanchez‐Garcia, Annelies Stevaert, Jan Münch   +24 more
wiley   +1 more source

Spatially precise chemo-radio-immunotherapy by antibody drug conjugate directed tumor radiosensitization to potentiate immunotherapies. [PDF]

NPJ Precis Oncol
Mortaja M, Adams SR, McKay RR, Gutkind JS, Advani SJ.   +4 more
europepmc   +1 more source