Results 21 to 30 of about 905,093 (362)
Blood, 2001 Receptors for human immunoglobulin (Ig)G and IgA initiate potent cytolysis of antibody (Ab)-coated targets by polymorphonuclear leukocytes (PMNs). Mac-1 (complement receptor type 3, CD11b/CD18) has previously been implicated in receptor cooperation with ...
A. Spriel +6 more
semanticscholar +1 more source
Assessment of intracanal medications cytotoxicity on L929 fibroblast cells
Bioscience Journal, 2016 This study aimed to evaluate the cytotoxicity of intracanal medications on L929 fibroblast cells at different periods of observation. The following experimental groups were studied: calcium hydroxide with camphorated paramonochlorophenol and glycerin ...
Michelle de Paula Farias +6 more
doaj +3 more sources
Cytotoxicity and genotoxicity of calcium silicate-based cements on an osteoblast lineage
Brazilian Oral Research, 2016 Several calcium silicate-based biomaterials have been developed in recent years, in addition to Mineral Trioxide Aggregate (MTA). The aim of this study was to evaluate the cytotoxicity, genotoxicity and apoptosis/necrosis in human osteoblast cells (SAOS ...
Ana Lívia GOMES-CORNÉLIO +7 more
doaj +1 more source
Cancer Research, 2006 The ability of cancers to evade immune surveillance and resist immunotherapy raises a fundamental question of how tumor cells survive in the presence of a competent immune system.
R. Ravi +12 more
semanticscholar +1 more source
Biomaterials Research, 2023 Tissue-engineered decellularized extracellular matrix (ECM) scaffolds hold great potential to address the donor shortage as well as immunologic rejection attributed to cells in conventional tissue/organ transplantation.
Mohammadreza Kasravi +7 more
doaj +1 more source
Stochastic model of T Cell repolarization during target elimination (I) [PDF]
, 2020 Cytotoxic T lymphocytes (T) and natural killer (NK) cells are the main cytotoxic killer cells of the human body to eliminate pathogen-infected or tumorigenic cells (i.e. target cells). Once a NK or T cell has identified a target cell, they form a tight contact zone, the immunological synapse (IS).
arxiv +1 more source
Journal of Investigative Dermatology, 1988 Human vitiligo is a common depigmenting disorder that is often associated with polyendocrinopathies. The etiology of vitiligo is unknown although there is indirect evidence of a strong association between antimelanocyte antibodies in animal and human ...
David A. Norris +3 more
semanticscholar +1 more source
Iranian Journal of Allergy, Asthma and Immunology, 2019 Stromal cell-derived factor-1 alpha (SDF-1α) has been shown to be up-regulated in a variety of malignancies. So that, its expression is associated with poor prognosis and invasiveness.
Alireza Mardomi +4 more
doaj +1 more source
Bayesian Models and Decision Algorithms for Complex Early Phase Clinical Trials [PDF]
Statistical Science 2010, Vol. 25, No. 2, 227-244, 2010 An early phase clinical trial is the first step in evaluating the effects in humans of a potential new anti-disease agent or combination of agents. Usually called "phase I" or "phase I/II" trials, these experiments typically have the nominal scientific goal of determining an acceptable dose, most often based on adverse event probabilities.
arxiv +1 more source
Lung tumor microenvironment induces specific gene expression signature in intratumoral NK cells
Frontiers in Immunology, 2013 Natural Killer (NK) cells are able to recognize and kill tumor cells, however whether they contribute to tumor immunosurveillance is still debated. Our previous studies demonstrated the presence of NK cells in human lung tumors.
Mélanie eGillard-Bocquet +22 more
doaj +1 more source