Results 41 to 50 of about 1,423 (137)
Медицинский совет, 2022 Infertility is defined as not being to get pregnant for a couple after at least a year of regular sexual life. The condition has become a global health issue affecting about 187 million couples worldwide, and about half of the cases are associated with ...
R. I. Ovchinnikov
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Cell Proliferation, EarlyView.In a DHEA+HFD‐induced mouse model, Ins/BBR alleviated mitochondrial defects and broadly reprogrammed metabolic landscape in granulosa cells, in specific, restoring nucleotide pools and amino acid turnover, and preventing abnormal long‐chain fatty acid accumulation.
Juan Ge +8 more
wiley +1 more source
Nexus of Whey Proteins, Gut Dysbiosis, and Colonic Health
Food Science &Nutrition, Volume 14, Issue 2, February 2026.Whey proteins possess antimicrobial and prebiotic properties that modulate gut microbiota by promoting beneficial bacteria like Bifidobacterium while suppressing pathogens. This modulation enhances short‐chain fatty acid production and strengthens intestinal barrier integrity, potentially alleviating dysbiosis‐related conditions such as colitis and ...
Tolulope Joshua Ashaolu +4 more
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Absorption and biosynthesis of D‐chiro‐inositol in mice
The FASEB Journal, 2009 D‐chiro‐inositol (DCI) is known to possess insulin‐like properties. Mice were fed with either regular chow (control group) or DCI‐free diet over a five‐week period. The levels of DCI declined significantly in plasma (1.91 ± 0.17 to 0.056 ± 0.0 μM), stool (20.2 ± 6 to 0.147 ± 0.05 nmoles) and urine (27.39 ± 8.2 ...
Chaya Gopalan +3 more
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Smart Medicine, Volume 5, Issue 1, February 2026.We provide the first comprehensive analysis of changes in the gut bacteriome at different clinical stages of HTLV‐1 infection. HTLV‐1 infection is associated with a dysbiosis that includes reduced bacterial diversity and an inverted Firmicutes/Bacteroidetes ratio.
Lorena Abreu Fernandes +8 more
wiley +1 more source
D-chiro-Inositol and Pinitol Extend the Life Span of Drosophila melanogaster [PDF]
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2012 D-chiro-inositol, a member of the inositol family, and pinitol, a 3-methoxy analogue of D-chiro-inositol, have been proposed to have antidiabetic, antiinflammatory, anticancer and stamina enhancing effects. We found that supplementing the diet of Drosophila with D-chiro-inositol and pinitol extended adult longevity in both male and female flies.
Binika, Hada +5 more
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D-Pinitol Improved Glucose Metabolism and Inhibited Bone Loss in Mice with Diabetic Osteoporosis
Molecules, 2023 Diabetic osteoporosis (DO) has been increasingly recognized as an important complication of diabetes. D-pinitol, a natural compound found in various legumes, is known for its anti-diabetic function, but its effect on DO has not been investigated.
Xinxin Liu, Tomoyuki Koyama
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The Concise Guide to PHARMACOLOGY 2025/26: Transporters
British Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +28 more
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Evaluation of the treatment with D-chiroinositol on levels of oxidative stress in pcos patients
Репродуктивная эндокринология, 2019 Recent studies on the pathophysiology of infertility have shown that oxidative stress (OS) can be one of the causal factors. The OS is, by definition, an imbalance between the production of reactive oxygen species and antioxidant defense systems.
В. Де Лео +2 more
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Food Science &Nutrition, Volume 13, Issue 9, September 2025.Supplements targeting adipose tissue inflammation may reduce obesity‐related cardiometabolic diseases. We tested whether Myo‐Inositol (MYO), a carbocyclic sugar with insulin‐sensitizing effects, reduces adipose tissue inflammation using an in vitro model of human adipocytes stimulated with TNF‐α.
Stefano Quarta +10 more
wiley +1 more source