Results 121 to 130 of about 1,177 (161)
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Pharmacological effects of
In recent years, the application of phytochemicals to prevent or treat diseases has received greater attention. These phytochemicals have little or no toxicity against healthy tissues and are thus considered as ideal compounds. An impressive number of modern drugs are obtained from natural sources based on their traditional value.
Anandakumar Pandi +6 more
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Revision of the pathway of d-pinitol formation in leguminosae
Phytochemistry, 1987Abstract Tracer studies with labelled inositols demonstrate that in contrast to earlier reports the formation of d -pinitol in Medicago sativa, Ononis spinosa and Trifolium incarnatum does not proceed by epimerization of sequoyitol but via d -ononitol.
Peter Dittrich, Andrea Brandl
exaly +3 more sources
d-Pinitol: a cyclitol with versatile biological and pharmacological activities
Phytochemistry Reviews, 2020d-Pinitol (3-O-methyl-d-chiro-inositol) is a cyclitol nearly ubiquitous in the Leguminosae and Pinaceae families. It plays an important role in plants as physiological cellular modulator and chemical defense against unfavorable environmental conditions, such as water deficit and high level of salinity.
Marina Sánchez-Hidalgo +4 more
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Protective effect of D-pinitol on the experimental spinal cord injury in rats
Metabolic Brain Disease, 2020Spinal cord injury (SCI) is the major cause of the spinal damage affecting motor and sensory function. Thus, the present study was conducted to investigate the effect of D-pinitol (PN) on spinal cord injury in rats. The PN showed to recover motor function near to normal via modulating oxidative stress, inflammatory response and cellular apoptosis in ...
Yan An +4 more
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PROTEOMICS – Clinical Applications, 2021
AbstractPurposeThe molecular mechanisms of diabetic cardiomyopathy (DCM) development and D‐pinitol (DP) in its treatment remain unclear. The present study is to explore the underlying mechanism of DCM in an elderly diabetic mouse model and to seek the protective targets of DP by phosphoproteomics.Experimental designWe used streptozotocin to induce ...
Xiao-Li, Li +5 more
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AbstractPurposeThe molecular mechanisms of diabetic cardiomyopathy (DCM) development and D‐pinitol (DP) in its treatment remain unclear. The present study is to explore the underlying mechanism of DCM in an elderly diabetic mouse model and to seek the protective targets of DP by phosphoproteomics.Experimental designWe used streptozotocin to induce ...
Xiao-Li, Li +5 more
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Synthesis of azole nucleoside analogues of d-pinitol as potential antitumor agents
Carbohydrate Research, 2007A convenient strategy is reported for the synthesis of azole nucleoside analogues of D-pinitol (=3-O-methyl-D-chiro-inositol). The key intermediate 3-O-methyl-4,5-epoxy-D-chiro-inositol was obtained in excellent yield via an epoxidation from mono-methanesulfonate of D-pinitol.
Tianrong, Zhan, Hongxiang, Lou
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d-pinitol inhibits Th1 polarization via the suppression of dendritic cells
International Immunopharmacology, 2007d-pinitol has been demonstrated to exert insulin-like and anti-inflammatory effects. However, the effects of the maturation and immunostimulatory functions of dendritic cells (DC) remain to be clearly elucidated. In this study, we have attempted to determine whether d-pinitol regulates surface molecule expression, cytokine production, endocytosis ...
Jun Sik, Lee +11 more
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D-Pinitol Protects Against Carbon Tetrachloride-Induced Hepatotoxicity in Rats
Journal of Environmental Pathology, Toxicology and Oncology, 2015The aim of the study was to evaluate the protective activity of D-Pinitol against carbon tetrachloride (CCl4)-induced hepatotoxicity in rats. The animals were divided into six groups, with each group consisting of six animals. Group I animals served as normal controls and received olive oil vehicle (1.0 ml/kg body weight intraperitoneally).
Thamaraiselvan, Rengarajan +4 more
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d-(+)-Pinitol, an oviposition stimulant for the pipevine swallowtail butterfly,Battus philenor
Journal of Chemical Ecology, 1992Oviposition by females of the pipevine swallowtail butterfly,Battus philenor, was stimulated by contact with alcoholic extracts of host foliage.D-(+)-Pinitol was isolated and identified from leaf material of one host species,Aristolochia macrophylla (Aristolochiaceae).
D R, Papaj +3 more
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Effect of D‐pinitol on
AbstractSchizophrenia is a chronic brain disorder characterized by positive symptoms (delusions or hallucinations), negative symptoms (impaired motivation or social withdrawal), and cognitive impairment. In the present study, we explored whether D‐pinitol could ameliorate schizophrenia‐like behaviors induced by MK‐801, an N‐methyl‐D‐aspartate receptor ...
Jae Youn Kim +8 more
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