Host-selected mutations converging on a global regulator drive an adaptive leap towards symbiosis in bacteria [PDF]
Host immune and physical barriers protect against pathogens but also impede the establishment of essential symbiotic partnerships. To reveal mechanisms by which beneficial organisms adapt to circumvent host defenses, we experimentally evolved ...
Cooper, Vaughn S. +8 more
core +3 more sources
Signalling and regulation of plant development by carbon/nitrogen balance
Abstract The two most abundant macronutrients in plant cells are carbon (C) and nitrogen (N). Coordination of their cellular metabolism is a fundamental factor in guaranteeing the optimal growth and development of plants. N availability and assimilation profoundly affect plant gene expression and modulate root and stem architecture, thus affecting ...
Iris Fañanás‐Pueyo +3 more
wiley +1 more source
Biosynthesis of rare hexoses using microorganisms and related enzymes
Rare sugars, referred to as monosaccharides and their derivatives that rarely exist in nature, can be applied in many areas ranging from foodstuffs to pharmaceutical and nutrition industry, or as starting materials for various natural products and drug ...
Zijie Li +4 more
doaj +1 more source
Synthesis of D-Sorbose and D-Psicose by RecombinantEscherichia coli [PDF]
GRAPHICAL ...
Cai, Li +3 more
openaire +1 more source
From Sweetness to Mouthfeel: A Review on Overcoming Sensory Barriers in Sugar‐Free Beverages
Background Over recent decades, considerable research has focused on understanding sweet taste mechanisms and developing new noncarbohydrate sweeteners due to rising noncommunicable diseases. New regulations limiting high sugar levels in food and beverages have driven innovation towards reduced‐sugar and sugar‐free products, often using noncarbohydrate
Imogen Ramsey +4 more
wiley +1 more source
Application-Oriented Marine Isomerases in Biocatalysis
The class EC 5.xx, a group of enzymes that interconvert optical, geometric, or positional isomers are interesting biocatalysts for the synthesis of pharmaceuticals and pharmaceutical intermediates.
Antonio Trincone
doaj +1 more source
Abstract The qualified presumption of safety (QPS) process was developed to provide a safety assessment approach for microorganisms intended for use in food or feed chains. In the period covered by this Statement, no new information was found that would change the status of previously recommended QPS taxonomic units (TUs).
EFSA Panel on Biological Hazards (BIOHAZ) +28 more
wiley +1 more source
Membrane-bound glycerol dehydrogenase catalyzes oxidation of D-pentonates to 4-keto-D-pentonates, D-fructose to 5-keto-D-fructose, and D-psicose to 5-keto-D-psicose [PDF]
Abstract A novel oxidation of D-pentonates to 4-keto-D-pentonates was analyzed with Gluconobacter thailandicus NBRC 3258. D-Pentonate 4-dehydrogenase activity in the membrane fraction was readily inactivated by EDTA and it was reactivated by the addition of PQQ and Ca2+. D-Pentonate 4-dehydrogenase was purified to two different subunits,
Ano, Yoshitaka +6 more
openaire +4 more sources
alpha-lipoic acid suppresses 6-hydroxydoparnine-induced ROS generation and apoptosis through the stimulation of glutathione synthesis but not by the expression of heme oxygenase-1 [PDF]
We previously reported that the generation of reactive oxygen species (ROS) is the initial event in cell death induced by 6-hydroxydopamine (6-OHDA), an experimental model of Parkinsonism.
Akagi, Reiko +9 more
core +1 more source
Exploiting Archaeal/Thermostable Enzymes in Synthetic Chemistry: Back to the Future?
Thermostable and (hyper)thermophilic enzymes offer important opportunities for innovative, stereoselective and sustainable chemistry transformations. Many of these are archaeal enzymes that have evolved to operate under extreme conditions, including at elevated temperature.
Gaurav P. Kudalkar +2 more
wiley +1 more source

