Results 261 to 270 of about 10,883,538 (292)
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Journal of the Society for Gynecologic Investigation, 2004
To investigate the possible role of human placenta in providing D-serine to the developing fetus.Expression of serine racemase in placenta was determined by reverse transcriptase polymerase chain reaction and northern analysis and confirmed by subsequent cloning.
Zhong, Chen +5 more
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To investigate the possible role of human placenta in providing D-serine to the developing fetus.Expression of serine racemase in placenta was determined by reverse transcriptase polymerase chain reaction and northern analysis and confirmed by subsequent cloning.
Zhong, Chen +5 more
openaire +2 more sources
Eukaryotic d-Serine Dehydratase
2016In mammals, d-serine is endogenously synthesized by serine racemase (SR), and it plays important roles in memory and learning by binding to the N-methyl-d-aspartate (NMDA) receptor and δ2 glutamate receptor. d-Amino acid oxidase (DAO) is the only mammalian enzyme that degrades d-serine.
Tomokazu Ito +3 more
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d-Serine and the Pathophysiology of Schizophrenia
2016Schizophrenia is a chronic, disabling psychiatric disorder characterized by psychosis, cognitive impairments, and negative symptoms such as social withdrawal and anhedonia. Pathologic changes in the brain include cortical atrophy, loss of pyramidal cell dendritic complexity and spine density, ventricular enlargement, and reduction in intracellular ...
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d-Serine Signaling and Schizophrenia
2016It has been widely accepted that the hypofunction of the N-methyl-d-aspartate-type glutamate receptor (NMDAR) may be implicated in the pathophysiology of both positive- and negative-cognitive symptomatologies of schizophrenia because NMDAR antagonists, including phencyclidine (PCP) and anti-NMDAR antibodies, mimic these respective antipsychotic ...
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Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer
Cell, 2020Robert S Banh +2 more
exaly
ATF3 promotes the serine synthesis pathway and tumor growth under dietary serine restriction
Cell Reports, 2021Lun Cai, Xiaoguang Chen, Junran Zhang
exaly
Serine metabolism orchestrates macrophage polarization by regulating the IGF1–p38 axis
Cellular and Molecular Immunology, 2022Xiao Shan, Penghui Hu, Zemin Ji
exaly
Disposition of D‐Serine in Healthy Adults
The Journal of Clinical Pharmacology, 2008Guochuan E, Tsai +5 more
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Serine Catabolism Feeds NADH when Respiration Is Impaired
Cell Metabolism, 2020Zihong Chen, Lin Wang, Cholsoon Jang
exaly
D-Serine dehydratase of earthworm tissues
Biochimica et Biophysica Acta (BBA) - Enzymology and Biological Oxidation, 1965D, Fujimoto, E, Adams
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