Results 231 to 240 of about 17,216 (256)

[DAMPs (damage-associated molecular patterns) and inflammation].

Nihon rinsho. Japanese journal of clinical medicine, 2016
Post-ischemic inflammation is re-appraised as an important player in the progression of ischemic stroke. Activation of inflammatory cells via Toll-like receptor 2 (TLR2) and TLR4 is caused by several damage-associated molecular patterns (DAMPs), including high mobility group box-1 (HMGB-1) and heat shock proteins.
Hiroaki, Ooboshi, Takashi, Shichita
openaire   +1 more source

DAMPs: Damage-Associated Molecular Pattern Molecules in Hemostasis

2016
This chapter explores the role of some of the key DAMPs in modulating the coagulation and fibrinolytic cascades, how they activate platelets, and modulate platelet functions. Potential mechanisms differentiating disseminated intravascular coagulation from thrombosis are discussed with an emphasis on the generation of procoagulant membrane remnants that
openaire   +1 more source

Role of Extracellular Damage-Associated Molecular Pattern Molecules (DAMPs) as Mediators of Persistent Pain

2015
Damage-associated molecular pattern molecules (DAMPs) are endogenous molecules that are constitutively expressed and released upon tissue damage, resulting in activation of the immune system. In the absence of injury or infection, DAMPs play important intracellular roles.
Jungo, Kato, Camilla I, Svensson
openaire   +2 more sources

Toll-Like Receptor 4 Activation by Damage-Associated Molecular Patterns (DAMPs)

2020
Mammalian toll-like receptors (TLRs) act as key sensors of pathogen-associated molecular patterns (PAMP), such as bacterial lipopolysaccharides (LPS), lipopeptides, and flagellin, which are molecular structures present in microbial cells but not in host cells.
Monica Molteni, Carlo Rossetti
openaire   +1 more source

Using the Expression of Damage-Associated Molecular Pattern (DAMP) for the Evaluation and Monitoring of the Critically Ill Polytrauma Patient

Clinical Laboratory, 2016
The critically ill polytrauma patient continues to be one of the most complex cases in the intensive care unit (ICU). The molecular damage is closely connected with the severe, specific pathophysiological imbalances, such as severe inflammation, infections, hypermetabolism, oxidative stress, and ultimately multiple organ dysfunction syndrome (MODS).The
Marius, Papurica, Alexandru F, Rogobete, Dorel, Sandesc, Carmen A, Cradigati, Mirela, Sarandan, Raluca, Dumache, Florin G, Horhat, Lavinia M, Bratu, Razvan, Nitu, Dan C, Crisan, Delia I, Horhat, Elena S, Popovici, Sonia, Tanasescu, Vlad, Daliborca, Ovidiu, Boruga, Ovidiu H, Bedreag   +15 more
openaire   +2 more sources

Mitochondrial damage-associated molecular patterns (DAMPs) in inflammatory bowel disease

2018
Background The inflammatory bowel diseases (IBD) ulcerative colitis (UC) and Crohn’s disease (CD) are chronic relapsing inflammatory disorders which have a rising incidence and cause significant morbidity. There are currently several treatment options with many more in the drug pipeline, but there are a lack of accurate biomarkers for decisions on ...
openaire   +2 more sources

Damage-associated molecular pattern (DAMP) molecules as mediators of systemic juvenile idiopathic arthritis

2009
Introduction: Systemic juvenile idiopathic arthritis (sJIA) is chronic childhood arthritis of unknown cause. Novel studies seem to point to deregulation of the innate immune system as the primary pathophysiological mechanism, thus making sJIA an auto-inflammatory disorder. Aim: To explore the involvement of alarmins in the pathogenesis of sJIA Patients
Malčić, Ivan, Lukić, Ivan Krešimir, Jelušić, Marija, Bukovac, Lana, Grčević, Danka   +4 more
openaire  

Role of Damage-Associated Molecular Pattern/Cell Death Pathways in Vaccine-Induced Immunity

Viruses, 2021
Sun Min Lee, Paul Y Kim, Eui Ho Kim
exaly  

Extracellular self-DNA as a damage-associated molecular pattern (DAMP) that triggers self-specific immunity induction in plants

Brain, Behavior, and Immunity, 2018
Martin Heil
exaly  

Targeting Damage-Associated Molecular Pattern Molecules (DAMPs) and DAMP Receptors in Melanoma

Methods in Molecular Biology, 2014
Brian A Boone, Michael T Lotze, Boone Brian A   +2 more
exaly