Results 71 to 80 of about 55,722 (248)

Targeting Danger Signals to Rescue Fibrosis. [PDF]

Am J Respir Cell Mol Biol, 2022
Tsoyi K, Rosas IO.
europepmc   +1 more source

Directivity of hearing of auditory danger signal emitted by overhead crane

, 2016
Background: The objective of the research has been to provide an answer to the question of what the possibilities of determining the direction of approach of the auditory danger signal emitted by an overhead crane appropriately are.
Rafał Młyński, Emil Kozłowski, Kozłowski, Emil, Młyński, Rafał   +3 more
core   +1 more source

Danger signals in traumatic hemorrhagic shock and new lines for clinical applications. [PDF]

Front Physiol, 2022
Dufour-Gaume F, Frescaline N, Cardona V, Prat NJ.   +3 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease

, 2016
Inflammation defines the progression of ALD from reversible to advanced stages. Translocation of bacterial LPS to the liver from the gut is necessary for alcohol-induced liver inflammation.
Iracheta-Vellve, Arvin, Szabo, Gyongyi, Petrasek, Jan, Saha, Banishree, Kodys, Karen, Fitzgerald, Katherine A, Kurt-Jones, Evelyn A., Satishchandran, Abhishek   +7 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Corrigendum to "Release of Danger Signals during Ischemic Storage of the Liver: A Potential Marker of Organ Damage?" [PDF]

Mediators Inflamm, 2022
Liu A, Jin H, Dirsch O, Deng M, Huang H, Bröcker-Preuss M, Dahmen U.   +6 more
europepmc   +1 more source

An endogenous danger detection system in "Arabidopsis thaliana": the AtPep peptides and their receptors

, 2014
Plants use a plethora of sophisticated detection systems to recognize a variety of attackers and to subsequently initiate defense responses. A well-known paradigm in this context is the perception of microbe-associated molecular patterns (MAMPs) by ...
Klauser, Dominik Roman
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Adaptor protein MyD88 confers the susceptibility to stress via amplifying immune danger signals. [PDF]

Brain Behav Immun, 2023
Yao XP, Ye J, Feng T, Jiang FC, Zhou P, Wang F, Chen JG, Wu PF.   +7 more
europepmc   +1 more source