Results 91 to 100 of about 55,722 (248)
, 2013 The innate immune response to viruses is initiated when specialized cellular sensors recognize viral danger signals. Here we show that truncated forms of viral genomes that accumulate in infected cells potently trigger the sustained activation of the ...
Won-keun Kim (478684) +15 more
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
The simultaneous perception of self- and non-self-danger signals potentiates plant innate immunity responses. [PDF]
Planta, 2022 Pastor V, Cervero R, Gamir J.
europepmc +1 more source
Danger signals for organized labor
Danger signals for organized laborThe International Labour and Radical History Pamphlet Collection consists of over 2200 pamphlets representing a broad spectrum of leftist opinion, including communists, socialists, liberal reformers, trade unionists ...
core
Mast cell responses to danger signals
, 2012 Detecting and responding to danger is a paramount function of the immune system. Compounds heralding danger can be divided into two groups: exogenous and endogenous danger signals.
Mattias Enoksson (18638293)
core
, 2014 SummaryDuring an infection, the body increases the output of mature immune cells in order to fight off the pathogen. Despite convincing evidence that hematopoietic stem and progenitor cells (HSPCs) can sense pathogens directly, how this contributes to ...
Zhao, Jimmy L. +6 more
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
COVID-19 Vaccination Limits Systemic Danger Signals in SARS-CoV-2 Infected Patients. [PDF]
Viruses, 2022 Angioni R +8 more
europepmc +1 more source
Death, destruction, danger and dendritic cells.
, 1999 Dendritic cells are known to be involved in recognition of foreign antigens and initiation of specific T-cell responses. The 'danger hypothesis' suggests that the immune system can also respond to endogenous signals of distress.
Austyn, Jonathan, Austyn, JM
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source