Results 11 to 20 of about 9,798 (259)

Structure of Dantrolene

Analytical Sciences: X-ray Structure Analysis Online, 2004
The title compound, C14H10N4O5·CH4O, is a direct-acting skeletal relaxant. The crystal, obtained as a methanol solvate, belongs to space group P1 with the cell dimensions a=7.92(3), b=9.93(4) and c=10.57(3)A, α=87.7(2), β=85.2(2) and γ=72.2(2)°. The final R value is 0.066. The molecule takes a planar and fully extended structure.
Rumiko Tanaka, Toshio Akimoto, Masayuki Haramura, Akito Tanaka, Noriaki Hirayama   +4 more
openalex   +4 more sources

Malignant hyperthermia crisis during scoliosis surgery in a pediatric cerebral palsy patient: a case of early recognition and successful intervention [PDF]

Frontiers in Pediatrics
BackgroundMalignant hyperthermia (MH) is a rare but life-threatening complication of general anesthesia, characterized by a hypermetabolic response that can lead to severe complications if not managed promptly. Patients with neuromuscular disorders, such
Saleh M. Kardm, Abdulmonem Alsiddiky, Asim J. Alamri, Ravi Shankar Reddy   +3 more
doaj   +2 more sources

Dantrolene [PDF]

Canadian Anaesthetists’ Society Journal, 1984
Beverley A. Britt
openalex   +4 more sources

Reconstitution of Dantrolene [PDF]

Anesthesiology, 1988
A. W. FOX, Helen Campbell
openalex   +3 more sources

The Effectiveness of a Mobile National Remote Emergency System for Malignant Hyperthermia in China: Retrospective Pre-Post Implementation Study

Journal of Medical Internet Research
BackgroundMalignant hyperthermia (MH) seriously threatens perioperative safety. Historically, limited awareness of MH among anesthesiologists and the unavailability of dantrolene have caused a high mortality rate of MH events in China.
Lingcan Tan, Hong Yu, Yunxia Zuo, Bin Liu, Tao Zhu, Xiaoqian Deng   +5 more
doaj   +2 more sources

Availability of dantrolene for the management of malignant hyperthermia crises: European Malignant Hyperthermia Group guidelines

British Journal of Anaesthesia, 2020
Philip M Hopkins
exaly   +2 more sources

Dantrolene – A review of its pharmacology, therapeutic use and new developments [PDF]

Anaesthesia, 2004
T. Krause, Mark U. Gerbershagen, M. Fiege, Ralf Weißhorn, Frank Wappler   +4 more
exaly   +2 more sources

Dantrolene Inhibition of Ryanodine Receptor Ca2+Release Channels [PDF]

Journal of Biological Chemistry, 2001
Fangyi Zhao, Pin Li, S. R. Wayne Chen, Charles F. Louis, Bradley R. Fruen   +4 more
exaly   +2 more sources

Hyperglycemia as an atypical finding of malignant hyperthermia: A case report and literature review. [PDF]

J Diabetes Investig
A 13‐month‐old toddler presented with an atypical symptom – hyperglycemia – during a malignant hyperthermia crisis. During MH, hyperglycemia may result from intracellular calcium leakage in muscle cells, suggesting a potential association between MH susceptibility and hyperglycemia.
Sun HJ, Chia YY, Huang YY, Sun JC, Wen CH.   +4 more
europepmc   +2 more sources

Discovery and Treatment of Action Potential-Independent Myotonia in Hyperkalemic Periodic Paralysis. [PDF]

Ann Clin Transl Neurol
ABSTRACT Objective Hyperkalemic periodic paralysis (hyperKPP) is characterized by attacks of transient weakness. A subset of hyperKPP patients suffers from transient involuntary contraction of muscle (myotonia). The goal of this study was to determine mechanisms causing myotonia in hyperKPP.
Dupont C, Deardorff A, Nawaz M, Voss AA, Rich MM.   +4 more
europepmc   +2 more sources