Results 41 to 50 of about 9,798 (259)
Malignant hyperthermia in a regional facility: A case study
Journal of Perioperative Nursing, 2020 Malignant hyperthermia (MH) is a rare hypermetabolic state that may be triggered by both anaesthesia and non-anaesthesia triggers. The main anaesthesia triggers for MH are the depolarising muscle relaxant suxamethonium and volatile anaesthetic gases. MH
Catherine Kleidon
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Drugs, 2020 SummaryDantrolene sodium or dantrolene1 is 1-[5-(nitrophenyl)furfurylidene] amino hydantoin sodium hydrate. It is indicated for use in chronic disorders characterised by skeletal muscle spasticity, such as spinal cord injury, stroke, cerebral palsy and ...
R. Pinder +3 more
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Early Recognition and Treatment of Malignant Hyperthermia in Pediatric Patient during Bronchoscopy
Case Reports in Anesthesiology, 2020 Malignant hyperthermia is a rare pharmacogenetic disorder triggered by depolarizing muscle relaxant and potent volatile anesthetic agents. An MH crisis is an emergency and life-threatening event requiring early recognition and prompt management ...
Warangkana Lapisatepun +1 more
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Dantrolene and lymphocytic lymphoma [PDF]
Postgraduate Medical Journal, 1980 Summary A patient is reported who was on prolonged treatment with dantrolene for spastic paraplegia; he developed a malignant lymphoma which led to his death.
J. S. Tucker, H. H. Wan
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Dantrolene reduces CaMKIIδC-mediated atrial arrhythmias.
Europace, 2020 AIMS In atrial fibrillation (AF), an increased diastolic Ca2+ leak from the sarcoplasmic reticulum (SR) mediated by calcium/calmodulin-dependent-protein-kinaseIIδC (CaMKII) can serve as a substrate for arrhythmia induction and persistence. Dantrolene has
S. Pabel +10 more
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Anesthesiology, 2020 Background: Overactivation of ryanodine receptors and the resulting impaired calcium homeostasis contribute to Alzheimer’s disease–related pathophysiology.
Yong Wang +5 more
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Approaches To Optimizing Dantrolene Neuroprotection For The Treatment Of Alzheimer's Disease.
Current Alzheimer Research, 2020 Alzheimer's Disease (AD), a neurodegenerative disorder with high incidence and mortality, is leading its way to the top of the list of the deadliest diseases [1], without an effective disease-modifying drug.
Matan Ben Abou, Liang Sun, Huafeng Wei
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Malignant hyperthermia in children [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2008 INTRODUCTION Malignant hyperthermia is a rare disease which is mainly an inherited autosomal dominant trait. It is characteristic for muscle rigidity, metabolism or respiratory acidosis, high values of serum creatine kinase.
Igrutinović Zoran +4 more
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Perioperative management of malignant hyperthermia during general anesthesia: A report of two cases
Clinical Case Reports, 2022 Malignant hyperthermia (MH) is a lethal complication associated with general anesthesia characterized by sudden onset, rapid progression, and high mortality.
Xiaowei Chi +5 more
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Caffeine and dobutamine challenge induces bidirectional ventricular tachycardia in normal rats
Heart Rhythm O2, 2020 Background: Bidirectional ventricular tachycardia (BD-VT) is an intriguing arrhythmia, characterized by a beat-to-beat alternation of the QRS polarity on electrocardiogram. Currently there is no simple BD-VT animal model.
Chenyu Zhang, BS, Youhua Zhang, MD, PhD
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