Results 81 to 90 of about 9,385 (245)
Malignant hyperthermia: current approaches to prevention and treatment
One of the most serious complications of modern anesthesia is malignant hyperthermia, which is a pharmacogenetic disease phenotype manifested by skeletal muscle hypermetabolism and rhabdomyolysis during or after general anesthesia with the use of inhaled
E. S. Kim+2 more
doaj +1 more source
The eco-compatible, base- and waste-free, energy-efficient, low-environmental-impact, gram-scale, mechanochemical preparation of marketed drugs such as nitrofurantoin (Furantin©), dantrolene (Dantrium©) and their structurally related derivatives is ...
E. Colacino+6 more
semanticscholar +1 more source
Mutism and rigidity due to antipsychotic‐induced catatonia improved by hemodialysis: A case report
We present a case of antipsychotic‐induced catatonia (AIC) due to intramuscular injection of haloperidol that was promptly improved by hemodialysis. This report suggests the potential role of hemodialysis in improving AIC. Abstract Background Catatonia is a psychomotor syndrome linked to various medical conditions.
Rintaro Fujii+4 more
wiley +1 more source
Management of serotonin syndrome (toxicity)
Serotonin syndrome (toxicity), resulting from an excessive accumulation of serotonin in the central nervous system, it can occur due to various factors such as the initiation of medication, overdose or drug interactions. Diagnosing serotonin toxicity presents challenges as there are no definitive criteria.
Angela L. Chiew, Geoffrey K. Isbister
wiley +1 more source
Recrudescência fatal de hipertermia maligna em lactente com síndrome de Moebius. Relato de caso
JUSTIFICATIVA E OBJETIVOS: A hipertermia maligna (HM) é uma desordem farmacogenética da musculatura esquelética, caracterizada por estado hipermetabólico após anestesia com succinilcolina e/ou agentes anestésicos voláteis.
Cláudia Regina Fernandes+4 more
doaj +1 more source
What We Already Know about This TopicPrompt availability of dantrolene is important for treating malignant hyperthermia and has resulted in lowered mortality ratesMaintaining a malignant hyperthermia cart and full treatment dose of dantrolene is ...
P. Ho+4 more
semanticscholar +1 more source
Biological Function and Mechanism of NAT10 in Cancer
N‐acetyltransferase 10 (NAT10) is an acetyltransferase that mediates the acetylation of proteins and RNA. NAT10 positively affects the proliferation, metastasis, invasion, and drug resistance of various cancers through the regulation of cancer‐related proteins and genes.
Yufeng Han+6 more
wiley +1 more source
Neuronopathic Gaucher disease (nGD) manifests as severe neurological symptoms in patients with no effective treatment available. Ryanodine receptors (Ryrs) are a family of calcium release channels on intracellular stores.
B. Liou+12 more
semanticscholar +1 more source
Abstract Background and Purpose Botulinum neurotoxin type A1 (BoNT/A) is one of the most potent neurotoxins known. At the same time, it is also one of the safest therapeutic agents used for the treatment of several human disorders and in aesthetic medicine.
Mickaël Machicoane+9 more
wiley +1 more source