Results 51 to 60 of about 1,978 (184)

Finally, PrEP choices! But will clients ever have a choice? [PDF]

J Int AIDS Soc
Journal of the International AIDS Society, Volume 28, Issue S2, July 2025.
Green KE, Ngure K, Eakle R, Phanuphak N, Reed J.   +4 more
europepmc   +2 more sources

Polymeric gels for intravaginal drug delivery [PDF]

, 2017
This document is the Accepted Manuscript version of the following article: Michael T. Cook, and Marc b. Brown, ‘Polymeric gels for intravaginal drug delivery’, Journal of Controlled Release, Vol. 270: 145-157, January 2018. Under embargo until 6 December
Brown, Marc, Cook, Michael
core   +2 more sources

Evaluating the potential impact and cost-effectiveness of dapivirine vaginal ring pre-exposure prophylaxis for HIV prevention.

PLoS ONE, 2019
BackgroundExpanded HIV prevention options are needed to increase uptake of HIV prevention among women, especially in generalized epidemics. As the dapivirine vaginal ring moves forward through regulatory review and open-label extension studies, the ...
Meghan Reidy, Elizabeth Gardiner, Carel Pretorius, Robert Glaubius, Kristine Torjesen, Katharine Kripke   +5 more
doaj   +1 more source

Characteristics of Women Enrolled into a Randomized Clinical Trial of Dapivirine Vaginal Ring for HIV-1 Prevention.

PLoS ONE, 2015
IntroductionWomen in sub-Saharan Africa are a priority population for evaluation of new biomedical HIV-1 prevention strategies. Antiretroviral pre-exposure prophylaxis is a promising prevention approach; however, clinical trials among young women using ...
Thesla Palanee-Phillips, Katie Schwartz, Elizabeth R Brown, Vaneshree Govender, Nyaradzo Mgodi, Flavia Matovu Kiweewa, Gonasagrie Nair, Felix Mhlanga, Samantha Siva, Linda-Gail Bekker, Nitesha Jeenarain, Zakir Gaffoor, Francis Martinson, Bonus Makanani, Sarita Naidoo, Arendevi Pather, Jessica Phillip, Marla J Husnik, Ariane van der Straten, Lydia Soto-Torres, Jared Baeten   +20 more
doaj   +1 more source

The cost-effectiveness of multi-purpose HIV and pregnancy prevention technologies in South Africa. [PDF]

, 2018
INTRODUCTION: A number of antiretroviral HIV prevention products are efficacious in preventing HIV infection. However, the sexual and reproductive health needs of many women extend beyond HIV prevention, and research is ongoing to develop multi-purpose ...
Cabrera Escobar, Maria A, Delany-Moretlwe, Sinead, Eakle, Robyn, Kilbourne-Brook, Maggie, Meyer-Rath, Gesine, Mvundura, Mercy, Quaife, Matthew, Terris-Prestholt, Fern, Vickerman, Peter   +8 more
core   +1 more source

Planning for decentralized, simplified prEP: Learnings from potential end users in Ga-Rankuwa, gauteng, South Africa

Frontiers in Reproductive Health, 2023
BackgroundIn South Africa, youth experience challenges with oral Pre-Exposure Prophylaxis (PrEP) access and uptake. Taking services out of healthcare settings has the potential to increase reach and overcome these challenges.
Paballo Mataboge, Susan Nzenze, Nqaba Mthimkhulu, Mbali Mazibuko, Alison Kutywayo, Vusile Butler, Nicolette Naidoo, Saiqa Mullick   +7 more
doaj   +1 more source

The influence of social constructs of hegemonic masculinity and sexual behaviour on acceptability of vaginal microbicides in Zambia [PDF]

, 2017
Vaginal microbicides are heralded as a woman’s HIV prevention method. This ethnographic study, conducted in a trial setting in Zambia, explored how the social construction of masculinity and sexual behaviour influenced the acceptability of vaginal ...
Bond, V, Dixey, R, Mweemba, O, White, AK
core   +2 more sources

“It’s already in your body and it’s preventing”: a qualitative study of African female adolescent’s acceptability and preferences for proxy HIV prevention methods in Cape Town, South Africa

BMC Public Health, 2023
Background Advances in biomedical HIV prevention will soon offer young women a choice of HIV prevention methods, including various pre-exposure prophylaxis (PrEP) modalities such as daily oral pills, dapivirine vaginal ring, and long-acting injectable ...
Lauren Fynn, Katherine Gill, Melissa Wallace, Millicent Atujuna, Menna Duyver, Penelope Ngcobo, Hans Spiegel, Alex Rinehart, Sybil Hosek, Linda-Gail Bekker   +9 more
doaj   +1 more source

Single-domain antibodies and their formatting to combat viral infections [PDF]

, 2018
Since their discovery in the 1990s, single-domain antibodies (VHHs), also known as NanobodiesA (R), have changed the landscape of affinity reagents. The outstanding solubility, stability, and specificity of VHHs, as well as their small size, ease of ...
Ballegeer, Marlies, De Vlieger, Dorien, Rossey, Iebe, Saelens, Xavier, Schepens, Bert   +4 more
core   +2 more sources

Clinical testing of antiretroviral drugs as future prevention against vaginal and rectal transmission of HIV infection – a review of currently available results

Acta Pharmaceutica, 2019
The original purpose of vaginally applied microbicides was to slow down the HIV epidemic among the population until an effective vaccination was developed.
Vysloužil Jakub, Kubová Kateřina, Tkadlečková Veronika Nováková, Vetchý David   +3 more
doaj   +1 more source