Results 41 to 50 of about 36,179 (151)
Anthracycline-induced cardiac toxicity: A clinical review
Indian Journal of Medical and Paediatric Oncology, 2019 Anthracyclines (ATCs) have a great efficacy against many types of cancer and is currently considered a cornerstone in the treatment of numerous pediatric and adult hematological and solid tumors.
Adil Abdelhameed Abbas +1 more
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The involvement of multiple ABC transporters in daunorubicin efflux in Streptomyces coeruleorubidus
Microbial BiotechnologyStreptomyces genus produces a large number of antibiotics, which are always synthesized by specific biosynthetic gene clusters (BGCs). To resist autotoxicity, transporters encoded by genes located within BGC occasionally pump antibiotic along with ...
Jianxin Dong +5 more
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Exploring the Immunomodulatory Effects of Liposomal Daunorubicin on Jurkat Cells: A Study of Apoptosis and Gene Expression in Co-Cultured MDA-MB-231 Cells [PDF]
Pharmaceutical SciencesBackground: Breast cancer represents a significant aspect of women’s health, constituting approximately 30% of cancers affecting them globally, with a mortality rate of around 15%.
Malik Kareem Shanan +3 more
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Daunorubicin induced Stevens‐Johnson syndrome: A case report
Clinical Case Reports, 2021 Clinicians should consider the possible association of Daunorubicin with Stevens‐Johnson syndrome (SJS), administer it with caution and promptly evaluate all subsequently developing cutaneous reactions with a high index of suspicion for Stevens‐Johnson ...
Preeti Shakya, Amit Sharma Nepal
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microRNAs and Acute Myeloid Leukemia Chemoresistance: A Mechanistic Overview
Frontiers in Oncology, 2017 Up until the early 2000s, a functional role for microRNAs (miRNAs) was yet to be elucidated. With the advent of increasingly high-throughput and precise RNA-sequencing techniques within the last two decades, it has become well established that miRNAs can
Martino Marco Gabra +2 more
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Self‐association of daunorubicin [PDF]
FEBS Letters, 1974 with cytoxic and antimitotic activities. Presently it is used in the treatment of acute leukemia [ 1 ] . A considerable body of evidence has been accum- ulated which is in agreement with the existence of an intercalative complex with the DNA [2], which results in inhibition of both enzymatic RNA and DNA synthesis [3,4].
Barthelemy-Clavey, Véronique +3 more
openaire +2 more sources
Drug Delivery, 2018 The number of blind and low vision persons in the US is projected to increase to 5.68 million by 2020. The eye diseases causing loss of vision are life-long, chronic, and often need protracted presence of therapeutics at the disease site to keep the ...
David Warther +7 more
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DIFFERENCES IN EX-VIVO CHEMOSENSITIVITY TO ANTHRACYCLINES IN FIRST LINE ACUTE MYELOID LEUKEMIA
Mediterranean Journal of Hematology and Infectious Diseases, 2019 BACKGROUND: Induction schedules in acute myeloid leukemia (AML) are based on combinations of cytarabine and anthracyclines. The choice of the anthracycline employed has been widely studied in multiple clinical trials showing similar complete remission ...
Juan Eduardo Megias-Vericat +26 more
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Frontiers in PharmacologyIntroductionAs a malignant hematological disease, the incidence of acute myeloid leukemia (AML) has exhibited an upward trend in recent years. Nevertheless, certain limitations persist in the treatment of AML.
Jie Luo +8 more
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Frontiers in Chemistry, 2020 Measuring the concentration of anticancer drugs in pharmacological and biological samples is a very useful solution to investigate the effectiveness of these drugs in the chemotherapy process.
Marzieh Alizadeh +4 more
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