Results 101 to 110 of about 15,822 (213)
Multifunctional role of DEAD-box helicase 41 in innate immunity, hematopoiesis and disease
Frontiers in ImmunologyDEAD-box helicases are multifunctional proteins participating in many aspects of cellular RNA metabolism. DEAD-box helicase 41 (DDX41) in particular has pivotal roles in innate immune sensing and hematopoietic homeostasis.
Jing Ma, Susan R. Ross
doaj +1 more source
A conformational change in the helicase core is necessary but not sufficient for RNA unwinding by the DEAD box helicase YxiN [PDF]
, 2017 Cooperative binding of ATP and RNA to DEAD-box helicases induces the closed conformation of their helicase core, with extensive interactions across the domain interface.
Karow, Anne R., Klostermeier, Dagmar
core
Rice SUV3 is a bidirectional helicase that binds both DNA and RNA [PDF]
, 2014 BACKGROUND: Helicases play crucial role in almost all the nucleic acid metabolism including replication, repair, recombination, transcription, translation, ribosome biogenesis and splicing and these processes regulate plant growth and development.
Mohammed Tarique +2 more
core +1 more source
Iflaviruses in arthropods: when small is mighty
Insect Science, EarlyView.Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia +3 more
wiley +1 more source
Role of the amino terminal RHAU-specific motif in the recognition and resolution of guanine quadruplex-RNA by the DEAH-box RNA helicase RHAU [PDF]
, 2017 Under physiological conditions, guanine-rich sequences of DNA and RNA can adopt stable and atypical four-stranded helical structures called G-quadruplexes (G4).
Akman, Steven A. +4 more
core
Molecular and cellular pathogenesis of melanoma initiation and progression [PDF]
, 2013 Melanoma is a malignant tumour of melanocytes, which can spread to other organs of the body resulting in severe and/or lethal malignancies. Melanocytes are pigment producing cells found in deep layer of the epidermis and are originated from melanocytes ...
Regad, T
core +1 more source
The multiple lives of DEAD-box RNA helicase DP103/DDX20/Gemin3
Biochemical Society Transactions, 2018 Gemin3, also known as DDX20 or DP103, is a DEAD-box RNA helicase which is involved in more than one cellular process. Though RNA unwinding has been determined in vitro, it is surprisingly not required for all of its activities in cellular metabolism. Gemin3 is an essential gene, present in Amoeba and Metazoa.
Curmi, Frank, Cauchi, Ruben J.
openaire +3 more sources
Integrative Zoology, EarlyView.Multi‐omics analysis reveals that herbivorous adaptation in Lordiphosa flies arises from coordinated interactions across the genome, transcriptome, and gut microbiota: genomic expansions of detoxification (e.g., cytochrome P450s) and carbohydrate metabolism gene families, transcriptomic upregulation of energy pathways like lipid oxidation and ...
Run Guo +4 more
wiley +1 more source
Water Biology and SecurityDEAD-box RNA helicases play critical roles in regulating RNA metabolism and gene expression in both prokaryotes and eukaryotes. In the filamentous, heterocyst-forming cyanobacterium Anabaena PCC 7120, two DEAD-box helicases, CrhB and CrhC, are present ...
Wen-Kai Li +7 more
doaj +1 more source
Conserved requirement for DEAD-box RNA helicase Gemin3 in Drosophila oogenesis [PDF]
, 2012 Background: DEAD-box RNA helicase Gemin3 is an essential protein since its deficiency is lethal in both vertebrates and invertebrates. In addition to playing a role in transcriptional regulation and RNA silencing, as a core member of the SMN (survival of
Cauchi, Ruben J.
core +3 more sources