Results 91 to 100 of about 10,061 (190)
Journal of Clinical Laboratory Analysis, EarlyView.This study developed an optimized multiplex RT‐MIRA assay for the simultaneous detection of EML4‐ALK variants, achieving single‐copy sensitivity. Unexpectedly, during the development of the reaction system, we discovered a “low‐concentration enhancement effect,” where reducing primer or probe concentrations within a specific range markedly improved ...
Xiao‐Dong Ren +10 more
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...
Fei Xu +4 more
wiley +1 more source
Plasmodium falciparum DDX31 is DNA helicase localized in nucleolus
Heliyon, 2019 Malaria is a major infectious disease and is responsible for millions of infections every year. As drug resistance strains of Plasmodium species are emerging, there is an urgent need to understand the parasite biology and identify new drug targets ...
Rahena Yasmin +3 more
doaj +1 more source
The multiple lives of DEAD-box RNA helicase DP103/DDX20/Gemin3
Biochemical Society Transactions, 2018 Gemin3, also known as DDX20 or DP103, is a DEAD-box RNA helicase which is involved in more than one cellular process. Though RNA unwinding has been determined in vitro, it is surprisingly not required for all of its activities in cellular metabolism. Gemin3 is an essential gene, present in Amoeba and Metazoa.
Curmi, Frank, Cauchi, Ruben J.
openaire +3 more sources
Enterovirus infections in children
Pediatric Investigation, EarlyView.Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Xiangpeng Chen +11 more
wiley +1 more source
The role of DEAD- and DExH-box RNA helicases in neurodevelopmental disorders
Frontiers in Molecular NeuroscienceNeurodevelopmental disorders (NDDs) represent a large group of disorders with an onset in the neonatal or early childhood period; NDDs include intellectual disability (ID), autism spectrum disorders (ASD), attention deficit hyperactivity disorders (ADHD),
Johannes Lederbauer +6 more
doaj +1 more source
Degron-mediated proteolysis of CrhR-like DEAD-box RNA helicases in cyanobacteria. [PDF]
J Biol Chem, 2022 Whitman BT +6 more
europepmc +1 more source
Yeast RNA helicases of the DEAD‐box family involved in translation initiation [PDF]
Biology of the Cell, 2003 AbstractRNA helicases of the DEAD‐box and related families have been found to be required for all processes involving RNA molecules. Biochemical and genetic analyses have shown that at least two RNA helicases are required for translation initiation in yeast.
openaire +3 more sources
PROTEOMICS, EarlyView.ABSTRACT Cold atmospheric plasma (CAP) is effective against a variety of microorganisms. Here, we described effects on an Escherichia coli strain isolated from hospital wastewater caused by treatment with physical plasma. E. coli GW‐AmxH19 was incubated in artificial wastewater and treated for 15 min with CAP.
Jörg Bernhardt +11 more
wiley +1 more source
Iflaviruses in arthropods: when small is mighty
Insect Science, EarlyView.Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia +3 more
wiley +1 more source