Results 151 to 160 of about 10,578 (207)

A Constellation of Fluorescent Biosensors to Illuminate the Galaxy of Protein Kinases

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Protein kinases (PKs) are enzymes that catalyze phosphorylation of protein substrates involved in a wide variety of biological signalling pathways. This review describes the different families and mechanisms of action and regulation of protein kinases, together with the different classes of fluorescent biosensors that have been engineered and ...
Timothe Abbura, May C. Morris
wiley   +1 more source

SART3 promotes homologous recombination repair by stimulating DNA-RNA hybrids removal and DNA end resection

Nature Communications
DNA–RNA hybrids triggered by double-strand breaks (DSBs) are crucial intermediates during DSB repair, and their timely resolution requires numbers of RNA helicases, including DEAD box 1 (DDX1).
Hui Fu, Min Huang, Honglin Wu, Hui Zheng, Yifei Gong, Lingyu Xing, Juanjuan Gong, Ruiyuan An, Qian Li, Xinyu Jie, Xiaolu Ma, Tie-Shan Tang, Caixia Guo   +12 more
doaj   +1 more source

Functions of DEAD box RNA helicases DDX5 and DDX17 in chromatin organization and transcriptional regulation. [PDF]

BMB Rep, 2018
Giraud G, Terrone S, Bourgeois CF.
europepmc   +1 more source

Cooperative binding of ATP and RNA induces a closed conformation in a DEAD box RNA helicase

, 2008
RNA helicases couple the energy from ATP hydrolysis with structural changes of their RNA substrates. DEAD box helicases form the largest class of RNA helicases and share a helicase core comprising two RecA-like domains.
Karow, A. R., Kohler, J., Theissen, B., Klostermeier, D., Gubaev, A.   +4 more
core  

DEAD-box RNA helicases Dbp2, Ded1 and Mss116 bind to G-quadruplex nucleic acids and destabilize G-quadruplex RNA. [PDF]

Chem Commun (Camb), 2019
Gao J, Byrd AK, Zybailov BL, Marecki JC, Guderyon MJ, Edwards AD, Chib S, West KL, Waldrip ZJ, Mackintosh SG, Gao Z, Putnam AA, Jankowsky E, Raney KD.   +13 more
europepmc   +1 more source

DEAD box RNA helicases are pervasive protein kinase interactors and activators. [PDF]

Genome Res
Hirth A, Fatti E, Netz E, Acebron SP, Papageorgiou D, Švorinić A, Cruciat CM, Karaulanov E, Gopanenko A, Zhu T, Sinning I, Krijgsveld J, Kohlbacher O, Niehrs C.   +13 more
europepmc   +1 more source

Functional interplay between DEAD-box RNA helicases Ded1 and Dbp1 in preinitiation complex attachment and scanning on structured mRNAs in vivo. [PDF]

Nucleic Acids Res, 2019
Sen ND, Gupta N, K Archer S, Preiss T, Lorsch JR, Hinnebusch AG.   +5 more
europepmc   +1 more source

A role for Gle1, a regulator of DEAD-box RNA helicases, at centrosomes and basal bodies. [PDF]

Mol Biol Cell, 2017
Jao LE, Akef A, Wente SR.
europepmc   +1 more source

Differential Activation Of Dead Box Rna Helicases Rhlb And Rhle By Hfq/srnas And Their Target Mrnas

, 2017
Number of small RNA (sRNA) gene regulators have mounted in E. coli over the years whereas the number of validated protein partners has not changed considerably. Hfq has remained the only well studied global regulatory partner of sRNAs in E. coli. However,
Kumar, Amit
core  

Understanding the interaction of hepatitis C virus with host DEAD-box RNA helicases. [PDF]

World J Gastroenterol, 2014
Upadya MH, Aweya JJ, Tan YJ.
europepmc   +1 more source