Results 131 to 140 of about 10,578 (207)

Transcript correlation analysis for the identification of novel plant genes involved in iron metabolism and beyond: what next?

Plant Biology, EarlyView.
Transcript correlation analysis allowed the identification of several key nodes in the complex regulatory network of plant iron metabolism. Abstract Arabidopsis thaliana was the first plant genome to be fully sequenced, almost a quarter of a century ago, thanks to The Arabidopsis Genome Initiative, with contributions from scientists worldwide.
I. Murgia, P. Morandini
wiley   +1 more source

Characterisation of the DEAD Box RNA-Helicase Dbp10

, 2023
Masterarbeit Universität Graz ...
openaire   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

The RNA helicase DDX3X is an essential mediator of innate antimicrobial immunity.

PLoS Pathogens, 2018
DExD/H box RNA helicases, such as the RIG-I-like receptors (RLR), are important components of the innate immune system. Here we demonstrate a pivotal and sex-specific role for the heterosomal isoforms of the DEAD box RNA helicase DDX3 in the immune ...
Daniel Szappanos, Roland Tschismarov, Thomas Perlot, Sandra Westermayer, Katrin Fischer, Ekaterini Platanitis, Fabian Kallinger, Maria Novatchkova, Caroline Lassnig, Mathias Müller, Veronika Sexl, Keiryn L Bennett, Michelle Foong-Sobis, Josef M Penninger, Thomas Decker   +14 more
doaj   +1 more source

DExD-box RNA-helicases in Listeria monocytogenes are important for growth, ribosomal maturation, rRNA processing and virulence factor expression

, 2014
RNA-helicases are proteins required for the unwinding of occluding secondary RNA structures, especially at low temperatures. In this work, we have deleted all 4 DExD-box RNA helicases in various combinations in the Gram-positive pathogen Listeria ...
Johansson, Jörgen, Caroline Bäreclev (683823), Karolis Vaitkevicius (257327), Bäreclev, Caroline, Jörgen Johansson (458315), Netterling, Sakura,, Netterling, Sakura, Vaitkevicius, Karolis, Bäreclev, Caroline,, Vaitkevicius, Karolis,, Sakura Netterling (683824)   +10 more
core   +1 more source

Acute capillary blood DNA methylation responses to swimming exercise in high‐performance male and female swimmers

Experimental Physiology, EarlyView.
Abstract Epigenetic markers, particularly DNA methylation, are promising tools for monitoring athlete health and training due to their role in cellular regulation, exercise responsiveness and molecular stability. However, exercise‐induced epigenetic changes in peripheral blood in trained individuals remain unexplored.
C. D. Goldsmith, N. G. Lawler, D. B. Pyne, M. Kozlovskaia, K. McGibbon, L. J. G. Mitchell, A. D. Govus   +6 more
wiley   +1 more source

Similar roles for yeast Dbp2 and Arabidopsis RH20 DEAD-box RNA helicases to Ded1 helicase in tombusvirus plus-strand synthesis

, 2012
Recruited host factors aid replication of plus-strand RNA viruses. In this paper, we show that Dbp2 DEAD-box helicase of yeast, which is a homolog of human p68 DEAD-box helicase, directly affects replication of Tomato bushy stunt virus (TBSV).
Nagy, Peter D., Barajas, Daniel, Peter D. Nagy, Nikolay Kovalev, Daniel Barajas, Kovalev, Nikolay   +5 more
core   +1 more source

How Do DICER1 Syndrome Mutations Disrupt Catalysis? Unveiling Dicer Metal Binding Architecture and Mechanism of Action Using MD Simulations and QM/MM Calculations

Journal of Computational Chemistry, Volume 47, Issue 18, July 5, 2026.
Dicer plays a vital role in gene regulation, making understanding its function critical for drug design and addressing human diseases. This article uses a combination of MD and QM/MM techniques to elucidate structural details of the Dicer–substrate complex, the Dicer catalytic mechanism, and the misfunction of DICER1‐syndrome‐causing mutants.
Dylan J. Nikkel, Stacey D. Wetmore
wiley   +1 more source

DNA Replication Errors Drive Genome‐Wide Small Inverted Triplication Dynamics

Advanced Science, Volume 13, Issue 37, 3 July 2026.
This study provides insight into the dynamic equilibrium mechanism of a novel structural variant, small inverted triplication (SIT), which is generated by misalignment of the 3’ flap generated under DNA replication stress with palindromic sequence. Alternatively, the end sequence may fold back on itself to form an inverted fragment.
Yi Lei, Yu Zhou, Haitao Sun, Hang Yuan, Xinyu Pei, Jessica D. Hess, Yao Yan, Zunsong Hu, Mian Zhou, Zhaohui Gu, Li Zheng, Xiwei Wu, Binghui Shen   +12 more
wiley   +1 more source

DDX21 Promotes Breast Cancer Growth and Metastasis via Stimulating RNAPII Elongation During Hypoxia

MedComm, Volume 7, Issue 7, July 2026.
DDX21 triggers CDK9 release from the 7SK RNP complex. DDX21‐CDK9 binding to HIFs drives transcriptional reprogramming during hypoxia. DDX21 enhances breast cancer progression and metastasis. Elevated DDX21 expression correlates with poor prognosis in breast cancer patients.
Guangqiang Li, Mingxia Deng, Leqing Zhu, Zhiwei Lei, Rong Guo, Xiong Liu, Renwang Chen, Xichun Xia, Qiong Wen, Yuanyuan Duan, Yan Chen, Zhinan Yin   +11 more
wiley   +1 more source