Results 51 to 60 of about 10,578 (207)

A Cold-Inducible DEAD-Box RNA Helicase from Arabidopsis thaliana Regulates Plant Growth and Development under Low Temperature. [PDF]

PLoS ONE, 2016
DEAD-box RNA helicases comprise a large family and are involved in a range of RNA processing events. Here, we identified one of the Arabidopsis thaliana DEAD-box RNA helicases, AtRH7, as an interactor of Arabidopsis COLD SHOCK DOMAIN PROTEIN 3 (AtCSP3 ...
Yuelin Liu, Daisuke Tabata, Ryozo Imai
doaj   +1 more source

Unwinding the Mechanisms of a DEAD-Box RNA Helicase in Cancer [PDF]

Journal of Molecular Biology, 2015
RNA helicases function in all organisms to manage the conformational states of RNAs of all stripes. The largest family of RNA helicases is the DEAD-box family, with 37 members in humans [1]. DEAD-box proteins interact with and manipulate RNAs that range from rRNAs, as they fold and assemble into ribosomes, to mRNAs as they are exported from the nucleus,
openaire   +2 more sources

BrDHC1, a Novel Putative DEAD-Box Helicase Gene, Confers Drought Tolerance in Transgenic Brassica rapa

Horticulturae, 2022
Drought can seriously hinder the growth of plants, resulting in reduced crop yield and quality. At present, the tolerance of DEAD-box helicases (DHC) to abiotic stresses, such as drought, high salinity, low temperature, and high temperature, has been ...
Gangqiang Cao, Huihui Gu, Wenjing Jiang, Zhaoran Tian, Gongyao Shi, Weiwei Chen, Baoming Tian, Xiaochun Wei, Luyue Zhang, Fang Wei, Zhengqing Xie   +10 more
doaj   +1 more source

Xp54 and related (DDX6-like) RNA helicases : roles in messenger RNP assembly, translation regulation and RNA degradation

, 2006
The DEAD-box RNA helicase Xp54 is an integral component of the messenger ribonucleoprotein (mRNP) particles of Xenopus oocytes. In oocytes, several abundant proteins bind pre-mRNA transcripts to modulate nuclear export, RNA stability and translational ...
Weston, A, Sommerville, John
core   +1 more source

The DEAD-box Protein Rok1 Orchestrates 40S and 60S Ribosome Assembly by Promoting the Release of Rrp5 from Pre-40S Ribosomes to Allow for 60S Maturation. [PDF]

PLoS Biology, 2016
DEAD-box proteins are ubiquitous regulators of RNA biology. While commonly dubbed "helicases," their activities also include duplex annealing, adenosine triphosphate (ATP)-dependent RNA binding, and RNA-protein complex remodeling. Rok1, an essential DEAD-
Sohail Khoshnevis, Isabel Askenasy, Matthew C Johnson, Maria D Dattolo, Crystal L Young-Erdos, M Elizabeth Stroupe, Katrin Karbstein   +6 more
doaj   +1 more source

A motif unique to the human DEAD-box protein DDX3 is important for nucleic acid binding, ATP hydrolysis, RNA/DNA unwinding and HIV-1 replication

, 2011
DEAD-box proteins are enzymes endowed with nucleic acid-dependent ATPase, RNA translocase and unwinding activities. The human DEAD-box protein DDX3 has been shown to play important roles in tumor proliferation and viral infections.
Di Cicco, Giulia, Maga, Giovanni, Giulia Di Cicco, Anna Garbelli, Beermann, Sandra, Dietrich, Ursula, Giovanni Maga, Ursula Dietrich, Sandra Beermann, Garbelli, Anna   +9 more
core   +1 more source

Thermostable Bioluminescent Intercalating Dyes for Real‐Time, Integrated Nucleic Acid Amplification and Detection

Angewandte Chemie, EarlyView.
We present a bioluminescent diagnostic platform that integrates DNA amplification and detection in a single step. The engineering of thermostable luciferase‐intercalating dye conjugates and controlled release of caged luciferin substrates enable real‐time, detection of attomolar concentrations of viral DNA within 30 min.
Yosta de Stigter, Harmen J. van der Veer, Sterre de Lignie, Robbert J. de Haas, Renko de Vries, Joost P. H. Schoeber, Anne J. M. Loonen, Adriaan J. C. van den Brule, Maarten Merkx   +8 more
wiley   +2 more sources

Recognition of two distinct elements in the RNA substrate by the RNA-binding domain of the T. thermophilus DEAD box helicase Hera

, 2013
DEAD box helicases catalyze the ATP-dependent destabilization of RNA duplexes. Whereas duplex separation is mediated by the helicase core shared by all members of the family, flanking domains often contribute to binding of the RNA substrate.
Wöhnert, Jens, Linden, Martin H., Rudolph, Markus G., Steimer, Lenz, Wurm, Jan Philip, Klostermeier, Dagmar   +5 more
core   +1 more source

Blocking tombusvirus replication through the antiviral functions of DDX17-like RH30 DEAD-box helicase.

PLoS Pathogens, 2019
Positive-stranded RNA viruses replicate inside cells and depend on many co-opted cellular factors to complete their infection cycles. To combat viruses, the hosts use conserved restriction factors, such as DEAD-box RNA helicases, which can function as ...
Cheng-Yu Wu, Peter D Nagy
doaj   +1 more source

Genome-wide comparative in silico analysis of the RNA helicase gene family in Zea mays and Glycine max: a comparison with Arabidopsis and Oryza sativa. [PDF]

PLoS ONE, 2013
RNA helicases are enzymes that are thought to unwind double-stranded RNA molecules in an energy-dependent fashion through the hydrolysis of NTP. RNA helicases are associated with all processes involving RNA molecules, including nuclear transcription ...
Ruirui Xu, Shizhong Zhang, Jinguang Huang, Chengchao Zheng   +3 more
doaj   +1 more source