Investigation of the guanine quadruplex resolving activity of the DEAH-box RNA helicase RHAU [PDF]
, 2012 Generally depicted as single- or double-stranded molecules, nucleic acids sequences can adopt various forms of stable secondary structures. In particular, guanine-riche sequence of DNA and RNA can form atypical four-stranded helical structures termed G ...
Lattmann, Simon
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DEAD-Box Helicase DDX6 Facilitated RIG-I-Mediated Type-I Interferon Response to EV71 Infection
Frontiers in Cellular and Infection Microbiology, 2021 Previous studies have shown that DEAD (Asp-Glu-Ala-Asp)-box RNA helicases play important roles in viral infection, either as cytosolic sensors of pathogenic molecules or as essential host factors against viral infection.
Rui Zhang +9 more
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DEAD-Box RNA helicases in Bacillus subtilis have multiple functions and act independently from each other. [PDF]
J Bacteriol, 2013 DEAD-box RNA helicases play important roles in remodeling RNA molecules and in facilitating a variety of RNA-protein interactions that are key to many essential cellular processes.
Lehnik-Habrink M +7 more
europepmc +2 more sources
Biological roles of DExH RNA helicase, RHAU [PDF]
, 2007 In this thesis, I have described the work carried out on a single protein called RHAU, dealing with aspects of protein localization in cells, the regulation of global gene expression by different mechanisms, and cellular stress-responses.
Iwamoto, Fumiko
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DEAD/H-Box Helicases in Immunity, Inflammation, Cell Differentiation, and Cell Death and Disease
Cells, 2022 DEAD/H-box proteins are the largest family of RNA helicases in mammalian genomes, and they are present in all kingdoms of life. Since their discovery in the late 1980s, DEAD/H-box family proteins have been a major focus of study.
Parimal Samir, Thirumala-Devi Kanneganti
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Die DEAD-box Helikase Hera aus "Thermus thermophilus". Untersuchung der Wechselwirkung mit Nukleinsäuren und der Helikaseaktivität [PDF]
, 2009 Hera ist eine DEAD-Box Helikase aus Thermus thermophilus. Wie bei vielen anderen DEADbox Helikasen auch, ist wenig über die physiologische Rolle von Hera bekannt.
Linden, Martin Hubert
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The DEAD-Box RNA Helicase Ded1 Is Associated with Translating Ribosomes
Genes, 2023 DEAD-box RNA helicases are ATP-dependent RNA binding proteins and RNA-dependent ATPases that possess weak, nonprocessive unwinding activity in vitro, but they can form long-lived complexes on RNAs when the ATPase activity is inhibited. Ded1 is a yeast DEAD-box protein, the functional ortholog of mammalian DDX3, that is considered important for the ...
Yeter-Alat, Hilal +4 more
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BMC Microbiology, 2012 Background Regulation of surface antigenic variation in Giardia lamblia is controlled post-transcriptionally by an RNA-interference (RNAi) pathway that includes a Dicer-like bidentate RNase III (gDicer).
Gargantini Pablo R +3 more
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Division of Labor in an Oligomer of the DEAD-Box RNA Helicase Ded1p [PDF]
Molecular Cell, 2015 Most aspects of RNA metabolism involve DEAD-box RNA helicases, enzymes that bind and remodel RNA and RNA-protein complexes in an ATP-dependent manner. Here we show that the DEAD-box helicase Ded1p oligomerizes in the cell and in vitro, and unwinds RNA as a trimer. Two protomers bind the single-stranded region of RNA substrates and load a third protomer
Putnam, Andrea A. +5 more
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Molecular characterization of DDX26, a human DEAD-box RNA helicase, located on chromosome 7p12
Brazilian Journal of Medical and Biological Research, 2001 DEAD-box proteins comprise a family of ATP-dependent RNA helicases involved in several aspects of RNA metabolism. Here we report the characterization of the human DEAD-box RNA helicase DDX26. The gene is composed of 14 exons distributed over an extension
A.A. Camargo +6 more
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