Results 11 to 20 of about 2,208 (222)

[1-Deamino-4-Cyclohexylalanine] Arginine Vasopressin: A Potent and Specific Agonist for Vasopressin V1b Receptors [PDF]

Endocrinology, 2002
To date, there are no vasopressin (VP) agonists that exhibit a high affinity and selectivity for the VP V1b receptor with respect to the V1a, V2, and oxytocin receptors. In this study, we describe the synthesis and pharmacological properties of [1-deamino-4-cyclohexylalanine] arginine vasopressin (d[Cha4]AVP).
Sylvain Derick, Ling Cheng, M.-J. Voirol, S. Stoev, Marco Giacomini, Nga Ching Wo, Hazel H. Szeto, Mohamed Ben Mimoun, M. I. San Andrés, Rolf C. Gaillard, Gilles Guillon, M. Manning   +11 more
openalex   +4 more sources

The effects of infusions of arginine vasopressin or 1‐deamino‐8‐D‐arginine vasopressin on common carotid vascular resistance in conscious, Long Evans rats [PDF]

British Journal of Pharmacology, 1989
Intravenous infusions of arginine vasopressin or 1‐deamino‐8‐d‐arginine vasopressin (DDAVP) were given to conscious, Long Evans rats chronically instrumented with bilateral, common carotid, pulsed Doppler probes and intravascular catheters. During infusion of vasopressin at 0.3 nmol min−1 there was an increase in common carotid vascular resistance ...
Sheila M. Gardiner, A.M. Compton, T. Bennett   +2 more
openalex   +4 more sources

Resistance of 1-deamino-(8-D-arginine)-vasopressin to in vitro degradation as compared with arginine vasopressin.

Endocrinologia Japonica, 1985
In order to elucidate the mechanism(s) responsible for the prolonged antidiuretic activity of 1-deamino-[8-D-arginine]-vasopressin (dDAVP), antidiuretic activities of dDAVP and arginine vasopressin (AVP) were determined in the rat following either oral administration or incubation with AVP-degrading enzymes and reagents. Oral administration of dDAVP to
Kuniaki Matsui, Tokihisa Kimura, Kozo Ota, K. Iitake, Masaru Shoji, Minoru Inoue, KAORU YOSHINAGA   +6 more
openalex   +5 more sources

DDAVP (desmopressin; 1‐deamino‐cys‐8‐d‐arginine‐vasopressin) treatment in children with haemophilia B [PDF]

British Journal of Haematology, 2000
We tested the response to desmopressin (1‐deamino‐cys‐8‐d‐arginine‐vasopressin; DDAVP) in four patients with haemophilia B [factor IX (F IX) at diagnosis 1·4–5%]. The activated partial thromboplastin time (aPTT) was significantly shortened in all patients.
Stephan Ehl, Thomas Severin, A. H. Sutor
openalex   +6 more sources

Vasopressin-Sensitive Aqp2 Regulation Mediated by the TAZ-NR4A1 Axis in Renal Collecting Duct Cells. [PDF]

FASEB J
The TAZ‐NR4A1 axis was identified as a critical regulator of vasopressin‐induced AQP2 expression, essential for water homeostasis. Conditional TAZ‐knockout mice showed polyuria and a significant decrease in AQP2 expression in collecting ducts. In mpkCCDc11 cells, TAZ knockdown significantly impaired vasopressin‐mediated AQP2 expression independently of
Choi HS, Jang HJ, Kim WY, Park SA, Park E, Jung HJ, Kwon TH.   +6 more
europepmc   +2 more sources

Urinary reabsorption in the rat kidney by anticholinergics

Scientific Reports, 2021
Anticholinergics, therapeutic agents for overactive bladder, are clinically suggested to reduce urine output. We investigated whether this effect is due to bladder or kidney urine reabsorption. Various solutions were injected into the bladder of urethane-
Hideki Oe, Hatsumi Yoshiki, Xinmin Zha, Hisato Kobayashi, Yoshitaka Aoki, Hideaki Ito, Osamu Yokoyama   +6 more
doaj   +1 more source

Desmopressin (DDAVP) use in patients with von Willebrand disease: A single‐centre retrospective review of test response and clinical outcomes

Haemophilia, Volume 29, Issue 4, Page 1095-1103, July 2023., 2023
Abstract Introduction Peri‐procedural management of von Willebrand disease (VWD) utilizes von Willebrand factor (VWF) concentrates or desmopressin (DDAVP) to increase VWF levels. DDAVP is safe, easily administered, and inexpensive. Currently, a consensus definition for adequate DDAVP response is lacking, and outcomes of peri‐procedural DDAVP use in VWD
Priya Chandrakumaran, Julia Hews‐Girard, Man‐Chiu Poon   +2 more
wiley   +1 more source

Depression and anxiety in persons with Von Willebrand disease

Haemophilia, Volume 29, Issue 2, Page 545-554, March 2023., 2023
Abstract Objective We assessed sociodemographic and clinical characteristics associated with depression and anxiety in individuals with Von Willebrand disease (VWD) aged ≥12 years. Methods The study collected data on patients’ sociodemographic, joint problems and health‐related quality of life (HRQoL) using EQ‐5D‐3L, 8‐item patient health questionnaire
Jonathan C. Roberts, Roshni Kulkarni, Peter A. Kouides, Robert F. Sidonio Jr., Shannon L. Carpenter, Barbara A. Konkle, Joanne Wu, Megan M. Ullman, Randall Curtis, Judith R. Baker, Nicole Crook, Michael B. Nichol   +11 more
wiley   +1 more source

A Newly Devised Vasopressin Drip Protocol in the Management of Chronic Central Diabetes Insipidus During Facial Transplantation Surgery

AACE Clinical Case Reports, 2018
: Objective: Titration of desmopressin can be challenging during complex, lengthy surgical procedures in patients with chronic central diabetes insipidus (DI). Arginine vasopressin (AVP) may be the preferred treatment modality in these settings.
Khawla F. Ali, MD, Vicente T. San Martin, MD, Lea El-Hage, MD, Christine Ahrens, PharmD, RPh, Kevin M. Pantalone, DO, Robert S. Zimmerman, MD, Laurence Kennedy, MD, Pratibha Rao, MD   +7 more
doaj   +1 more source

Vasopressin effectively suppresses male fertility. [PDF]

PLoS ONE, 2013
Arginine vasopressin (VP) is neurohypophysial hormone has been implicated in stimulating contractile activity of the male reproductive tract in the testis. Higher levels of VP decrease sperm count and motility.
Woo-Sung Kwon, Yoo-Jin Park, Yun-Hee Kim, Young-Ah You, In Cheul Kim, Myung-Geol Pang   +5 more
doaj   +1 more source