Efficacy of adjusted weight-based dosing of desmopressin (1-deamino-8-d-arginine vasopressin in type 1 von Willebrand disease. [PDF]
Introduction VonWillebrand disease (VWD), the most common inherited bleeding disorder, is a heterogeneous condition caused by a deficiency or defect in von Willebrand factor (VWF).
Seaman CD.
europepmc +3 more sources
[1-deamino-4-cyclohexylalanine] arginine vasopressin: a potent and specific agonist for vasopressin V1b receptors. [PDF]
To date, there are no vasopressin (VP) agonists that exhibit a high affinity and selectivity for the VP V1b receptor with respect to the V1a, V2, and oxytocin receptors. In this study, we describe the synthesis and pharmacological properties of [1-deamino-4-cyclohexylalanine] arginine vasopressin (d[Cha4]AVP).
S. Derick +11 more
semanticscholar +4 more sources
In order to elucidate the mechanism(s) responsible for the prolonged antidiuretic activity of 1-deamino-[8-D-arginine]-vasopressin (dDAVP), antidiuretic activities of dDAVP and arginine vasopressin (AVP) were determined in the rat following either oral administration or incubation with AVP-degrading enzymes and reagents. Oral administration of dDAVP to
K. Matsui +6 more
semanticscholar +5 more sources
DDAVP (desmopressin; 1‐deamino‐cys‐8‐d‐arginine‐vasopressin) treatment in children with haemophilia B [PDF]
We tested the response to desmopressin (1‐deamino‐cys‐8‐d‐arginine‐vasopressin; DDAVP) in four patients with haemophilia B [factor IX (F IX) at diagnosis 1·4–5%]. The activated partial thromboplastin time (aPTT) was significantly shortened in all patients.
S. Ehl, T. Severin, A. Sutor
semanticscholar +5 more sources
Cyclic-AMP regulates postnatal development of neural and behavioral responses to NaCl in rats. [PDF]
During postnatal development rats demonstrate an age-dependent increase in NaCl chorda tympani (CT) responses and the number of functional apical amiloride-sensitive epithelial Na+ channels (ENaCs) in salt sensing fungiform (FF) taste receptor cells ...
Jie Qian +12 more
doaj +5 more sources
The effects of infusions of arginine vasopressin or 1‐deamino‐8‐D‐arginine vasopressin on common carotid vascular resistance in conscious, Long Evans rats [PDF]
Intravenous infusions of arginine vasopressin or 1‐deamino‐8‐d‐arginine vasopressin (DDAVP) were given to conscious, Long Evans rats chronically instrumented with bilateral, common carotid, pulsed Doppler probes and intravascular catheters. During infusion of vasopressin at 0.3 nmol min−1 there was an increase in common carotid vascular resistance ...
S M, Gardiner, A M, Compton, T, Bennett
openaire +4 more sources
Management of pregnancy and childbirth in Glanzmann thrombasthenia: A case series and review [PDF]
To illustrate the challenges in the management of women with Glanzmann thrombasthenia (GT) planning a pregnancy, we conducted a literature review and present a case series of eight women giving detailed descriptions of reproductive health problems, platelet alloimmunisation, treatment to prevent post‐partum haemorrhage and neonatal outcomes.
Karlijn H. G. Rutten +9 more
wiley +2 more sources
Desmopressin use in major cardiac surgery is associated with renal impairment: a retrospective single-center analysis [PDF]
Background Desmopressin acetate (1-deamino-8-d-arginine vasopressin—DDAVP) is a analogue of the antidiuretic hormone vasopressin. DDAVP is suggested to reduce bleeding after cardiac surgery using cardiopulmonary bypass.
Andreas Koköfer +5 more
doaj +2 more sources
1. Anterolateral cut (ALC) of the medial basal hypothalamus (MBH) in rats produces an elevation of plasma catecholamine levels, especially of norepinephrine (NE), in unstressed animals and a more pronounced rise of plasma NE levels in response to immobilization (IMO).
R, Kvetnanský +4 more
openaire +4 more sources
Vasopressin‐Sensitive Aqp2 Regulation Mediated by the TAZ‐NR4A1 Axis in Renal Collecting Duct Cells [PDF]
The TAZ‐NR4A1 axis was identified as a critical regulator of vasopressin‐induced AQP2 expression, essential for water homeostasis. Conditional TAZ‐knockout mice showed polyuria and a significant decrease in AQP2 expression in collecting ducts. In mpkCCDc11 cells, TAZ knockdown significantly impaired vasopressin‐mediated AQP2 expression independently of
Hong Seok Choi +6 more
wiley +2 more sources

