Results 51 to 60 of about 18,940 (249)
The Preventive Effect of Decorin on Epidural Fibrosis and Epidural Adhesions After Laminectomy
Frontiers in Pharmacology, 2021 Laminectomy is commonly performed to treat degenerative spinal diseases by reducing compression on the spinal cord and nerve roots. The postoperative epidural fibrosis and epidural adhesions may result in failed back surgery syndrome, which is ...
Qing Ding +11 more
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Frontiers in Cell and Developmental Biology, 2021 Hepatocellular carcinoma (HCC) is a common malignancy worldwide, and the high ratio of recurrence and metastasis remains the main cause of its poor prognosis. Vascular invasion of HCC includes microvascular invasion (MVI) and portal vein tumor thrombosis
Xiaobo Zheng +12 more
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Overexpressed Decorin in Pancreatic Cancer [PDF]
, 2004 Purpose: The aim of this study was to investigate the expression and significance of decorin in pancreatic cancer.Experimental Design: Decorin expression in normal pancreas and excised tumors was examined by real-time quantitative PCR, Western blot ...
Friess, Helmut +8 more
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Decorin as a possible strategy for the amelioration of COVID-19
Medical Hypotheses, 2021 Coronavirus pandemic has emerged as an extraordinary healthcare crisis in modern times. The SARS-CoV-2 novel coronavirus has high transmission rate, is more aggressive and virulent in comparison to previously known coronaviruses. It primarily attacks the
Prince Allawadhi +10 more
semanticscholar +1 more source
Dichotomy of decorin activity on the insulin-like growth factor-I system [PDF]
, 2013 The stromal-specific proteoglycan decorin has emerged in recent years as a critical regulator of tumor initiation and progression. Decorin regulates the biology of various types of cancer by modulating the activity of several receptor tyrosine kinases ...
Neill, Thomas +3 more
core +1 more source
The Scientific World Journal, 2006 The small leucine-rich proteoglycan (SLRP) decorin is efficiently internalized by a variety of cultured cells. A 51-kDa protein has previously been described as a receptor mediating endocytosis of decorin and of the structurally related SLRP biglycan ...
David Denis Sofeu Feugaing +3 more
doaj +1 more source
Indian Journal of Pathology and Microbiology, 2013 Background: Decorin is an extracellular matrix, multifunctional small proteoglycan molecule in tumor stroma that has been shown to be modulator of angiogenesis.
Seema Nayak +8 more
doaj +1 more source
Decorin deficiency promotes hepatic carcinogenesis [PDF]
, 2015 Hepatocellular carcinoma represents one of the most-rapidly spreading cancers in the world. In the majority of cases, an inflammation-driven fibrosis or cirrhosis precedes the development of the tumor.
Fullár, Alexandra +6 more
core +1 more source
Solar ultraviolet irradiation induces decorin degradation in human skin likely via neutrophil elastase. [PDF]
PLoS ONE, 2013 Exposure of human skin to solar ultraviolet (UV) irradiation induces matrix metalloproteinase-1 (MMP-1) activity, which degrades type I collagen fibrils. Type I collagen is the most abundant protein in skin and constitutes the majority of skin connective
Yong Li +5 more
doaj +1 more source
89A novel ocular function for decorin in the aqueous humor outflow.
Matrix Biology, 2021 Primary open-angle glaucoma a neurodegenerative disorder characterized by degeneration of optic nerve axons, is a frequent cause of vision loss and blindness worldwide.
Magdalena Schneider +9 more
semanticscholar +1 more source