Results 91 to 100 of about 18,800 (200)

Dectin-1 binding to annexins on apoptotic cells induces peripheral immune tolerance via NADPH oxidase-2

open access: yes, 2019
Summary Uptake of apoptotic cells (ACs) by dendritic cells (DCs) and induction of a tolerogenic DC phenotype is an important mechanism for establishing peripheral tolerance to self-antigens.
Bode, K.   +9 more
core   +1 more source

Titan cell production in Cryptococcus neoformans reshapes the cell wall and capsule composition during infection [PDF]

open access: yes, 2018
This work was supported by the National Institutes of Health (R01AI080275 and R21AI22352), the NIH Fogarty International Center (R25TW009345), the University of Minnesota Center for Translational Science Institute (UL1TR000114), Wellcome Trust (086827 ...
Gow, Neil A R   +5 more
core   +1 more source

Update on diagnosis, nonpharmacological treatment and prevention of Equine Gastric Ulcer Syndrome (EGUS)

open access: yesEquine Veterinary Education, Volume 38, Issue 4, Page 206-219, April 2026.
Summary The term Equine Gastric Ulcer Syndrome (EGUS) has been used since 1999. As there are important differences, the terms Equine Squamous Gastric Disease (ESGD) and Equine Glandular Gastric Disease (EGGD) were introduced in 2015. Risk factors like dietary management, training regimens and drug side effects, as described for NSAIDs, predispose ...
R. Lensing, A. K. Barton
wiley   +1 more source

Inhibition of Dectin-1 Alleviates Neuroinflammatory Injury by Attenuating NLRP3 Inflammasome-Mediated Pyroptosis After Intracerebral Hemorrhage in Mice: Preliminary Study Results

open access: yesJournal of Inflammation Research, 2022
Zhiquan Ding1 *, Zhenzhong Zhong1 *, Jun Wang1 *, Run Zhang,2 Jinlian Shao,3 Yulong Li,1 Guiwei Wu,1 Huiru Tu,1 Wen Yuan,4 Haitao Sun,1,5 Qinghua Wang1,3 1Neurosurgery Center, Department of Neurotrauma and Neurocritical Care Medicine ...
Ding Z   +10 more
doaj  

Advancing the Landscape of RNAi Nanotherapeutics for Ischemic Heart Disease

open access: yesAdvanced Materials, Volume 38, Issue 17, 20 March 2026.
RNA interference (RNAi) nanomedicine revolutionizes treatment regimens for ischemic heart diseases by enabling tailored, sequence‐anchored gene regulation. This review highlights the recent advances in nanotechnology‐driven RNAi therapeutics for myocardial ischemia and discusses the key design principles that govern efficient delivery, providing ...
Han Gao, Da Pan, Hélder A. Santos
wiley   +1 more source

Therapeutic targeting of MALT1 in oncology: Mechanism, inhibitor development, and clinical prospects

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 1, March 2026.
Abstract MALT1, a multifunctional protease molecule, plays a pivotal role in the adaptive immunity by regulating immune cell survival, proliferation and activation through the nuclear transcription factor‐κB (NF‐κB) signaling pathway by scaffold and protease activities.
Xintao Cao   +4 more
wiley   +1 more source

Characterization of C-type lectins reveals an unexpectedly limited interaction between Cryptococcus neoformans spores and Dectin-1.

open access: yesPLoS ONE, 2017
Phagocytosis by innate immune cells is an important process for protection against multiple pathologies and is particularly important for resistance to infection.
Naomi M Walsh   +4 more
doaj   +1 more source

Intestinal fungi contribute to development of alcoholic liver disease [PDF]

open access: yes, 2017
This study was supported in part by NIH grants R01 AA020703, U01 AA021856 and by Award Number I01BX002213 from the Biomedical Laboratory Research & Development Service of the VA Office of Research and Development (to B.S.). K.H.
Ali Keshavarzian   +37 more
core   +3 more sources

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

open access: yesThe FEBS Journal, Volume 293, Issue 6, Page 1587-1611, March 2026.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza   +4 more
wiley   +1 more source

Dectin-1 expression at early period of Aspergillus fumigatus infection in rat’s corneal epithelium

open access: yesInternational Journal of Ophthalmology, 2013
AIM:To investigate the expression of dendritic cell-associated C-type lectin-1(dectin-1) at the early period of Aspergillus fumigatus infection in rat’s corneal epithelium.METHODS:A total of 72 Wistar rats were randomly divided into three groups:A, B ...
Cheng-Ye Che
doaj   +1 more source

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