A genome-wide association study for somatic cell score using the Illumina high-density bovine beadchip identifies several novel QTL potentially related to mastitis susceptibility [PDF]
, 2013 peer-reviewedMastitis is an inflammation-driven disease of the bovine mammary gland that occurs in response to physical damage or infection and is one of the most costly production-related diseases in the dairy industry worldwide.
Alan eFahey +7 more
core +2 more sources
Egyptian Rheumatology and Rehabilitation, 2020 Background Behcet’s disease (BD) is associated with uveitis, oral ulcers, genital ulcers and arthritis. Enhanced activity of innate immunity components, such as neutrophils, natural killer (NK) cells and endothelial cells, is a prominent feature of BD ...
Reham M. Shaat +4 more
doaj +1 more source
New Phosphated Poly(methyl Methacrylate) Polymers for the Prevention of Denture-induced Microbial Infection: an In Vitro Study [PDF]
, 2011 Purpose: Poly(methyl methacrylate) (PMMA) has been widely used as a denture-base acrylic resin due to its excellent physical and mechanical properties.
Dentino, Andrew R., Raj, Antony
core +3 more sources
Functional Insights From the Evolutionary Diversification of Big Defensins
Frontiers in Immunology, 2020 Big defensins are antimicrobial polypeptides believed to be the ancestors of β-defensins, the most evolutionary conserved family of host defense peptides (HDPs) in vertebrates.
Marco Gerdol +5 more
doaj +1 more source
Flagellin induces β-defensin 2 in human colonic ex vivo infection with enterohemorrhagic Escherichia coli [PDF]
, 2016 Enterohemorrhagic E. coli (EHEC) is an important foodborne pathogen in the developed world and can cause life-threatening disease particularly in children.
Chan, Simon +6 more
core +1 more source
β-defensins and the epididymis: contrasting influences of prenatal, postnatal, and adult scenarios
Asian Journal of Andrology, 2016 β-defensins are components of host defense, with antimicrobial and pleiotropic immuno-modulatory properties. Research over the last 15 years has demonstrated abundant expression of a variety of β-defensins in the postnatal epididymis of different species.
Camilla M Ribeiro +3 more
doaj +1 more source
Mechanisms and regulation of defensins in host defense
Signal Transduction and Targeted Therapy, 2023 As a family of cationic host defense peptides, defensins are mainly synthesized by Paneth cells, neutrophils, and epithelial cells, contributing to host defense.
Jie Fu +5 more
doaj +1 more source
Computational and Structural Biotechnology Journal, 2021 Defensins are small proteins, usually ranging from 3 to 6 kDa, amphipathic, disulfide-rich, and with a small or even absent hydrophobic core. Since a hydrophobic core is generally found in globular proteins that fold in an aqueous solvent, the peculiar ...
Mariana H. Moreira +3 more
doaj +1 more source
Defensin-driven viral evolution.
PLoS Pathogens, 2020 Enteric alpha-defensins are potent effectors of innate immunity that are abundantly expressed in the small intestine. Certain enteric bacteria and viruses are resistant to defensins and even appropriate them to enhance infection despite neutralization of
Karina Diaz +7 more
doaj +1 more source
Large-scale Synthesis and Functional Elements for the Antimicrobial Activity of Defensins [PDF]
, 2000 Human neutrophil defensins, and their analogues incorporating anionic, hydrophobic or cationic residues at the N- and C-termini, were synthesized by solid-phase procedures.
Antonyraj, K. J. +2 more
core +3 more sources