Results 41 to 50 of about 42,453 (236)
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
FEBS Open Bio, EarlyView.The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
DEFENSINS-a AT AN EARLY AGE IN RATS WITH ACUTE SOMATIC PAIN
RUDN Journal of Medicine, 2019 This article presents the results of studies on the reaction of α-defensins to acute somatic pain in newborn rats and in the early puberty period. Studies were carried out on white mongrel rats for three hours after pain exposure.
I. M. Bykov, V. V. Alekseev
doaj +1 more source
Current Status of Defensins and Their Role in Innate and Adaptive Immunity [PDF]
, 2002 Naturally occurring antimicrobial cationic polypeptides play a major role in innate and adaptive immunity. These polypeptides are found to be either linear and unstructured or structured through disulfide bonds.
Dentino, Andrew R., Raj, Periathamby A.
core +1 more source
Skin microbiota: a source of disease or defence?
, 2008 Microbes found on the skin are usually regarded as pathogens, potential pathogens or innocuous symbiotic organisms. Advances in microbiology and immunology are revising our understanding of the molecular mechanisms of microbial virulence and the specific
Cogen, AL, Gallo, RL, Nizet, V
core +1 more source
Advanced Functional Materials, EarlyView.Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou +11 more
wiley +1 more source
Defensins of Grasses: A Systematic Review
Biomolecules, 2020 The grass family (Poaceae) is one of the largest families of flowering plants, growing in all climatic zones of all continents, which includes species of exceptional economic importance.
Tatyana I. Odintsova +2 more
doaj +1 more source
Cationic Polystyrene Resolves Nonalcoholic Steatohepatitis, Obesity, and Metabolic Disorders by Promoting Eubiosis of Gut Microbiota and Decreasing Endotoxemia. [PDF]
, 2017 A pandemic of metabolic diseases, consisting of type 2 diabetes, nonalcoholic fatty liver disease, and obesity, has imposed critical challenges for societies worldwide, prompting investigation of underlying mechanisms and exploration of low-cost and ...
Bai, Li +22 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales +11 more
wiley +1 more source
Antifungal defensins and their role in plant defense
Frontiers in Microbiology, 2014 Since the beginning of the 90’s lots of cationic plant, cysteine-rich antimicrobial peptides (AMP) have been studied. However, Broekaert only coined the term plant defensin in 1995, after comparison of a new class of plant antifungal peptides with known
Ariane eLacerda +4 more
doaj +1 more source
Animals, 2023 β-Defensins are cationic antimicrobial peptides (AMPs) that play an important role in the innate immune defense of bovines. They are constitutively expressed in mammary glands and induced differently in response to pathogens.
Mojtaba Daneshi +4 more
doaj +1 more source