Results 91 to 100 of about 1,660 (170)
Modulación histaminérgica de la corriente ASIC en neuronas aferentes vestibulares [PDF]
, 2018 "El sistema vestibular detecta aceleraciones angulares y lineales, gracias a los cinco órganos que lo conforman, tres canales semicirculares y dos órganos otolíticos.
Sánchez Martínez, Salomón +1 more
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ENaC/Degenerin family members reduces glioblastoma whole well current and inhibits cell migration
The FASEB Journal, 2008 High‐grade gliomas display a basally active, amiloride sensitive current not seen in normal astrocytes or low‐grade gliomas. We hypothesize that this glioma current is mediated by a hybrid channel composed of a mixture of Epithelial Sodium Channel (ENaC)/ Degenerins (Deg) subunits.
Niren Kapoor +2 more
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Subunit composition of a DEG/ENaC mechanosensory channel of Caenorhabditis elegans [PDF]
, 2015 Caenorhabditis elegans senses gentle touch in the six touch receptor neurons (TRNs) using a mechanotransduction complex that contains the pore-forming degenerin/epithelial sodium channel (DEG/ENaC) proteins MEC-4 and MEC-10. Past work has suggested these
Bharill, Shashank +3 more
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Small Molecule Inhibitors of Acid Sensing Ion Channel-1 [PDF]
, 2010 Acid Sensing Ion Channel 1 is one of the many proteins in the Epithelial Sodium Channel/Degenerin family. The proteins in this family interact to form cation channels with unique biophysical properties and can all be inhibited by the small molecule ...
Qadri, Yawar J
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Acid-sensing ion channels and migraine
Chinese Journal of Contemporary Neurology and Neurosurgery, 2015 Acid-sensing ion channels (ASICs) are ligand-gated ion channels that are activated by extracellular protons (H+), which belong to epithelial sodium channels/degenerin (ENaC/DEG) superfamily.
Yu-qi KANG, Zu-neng LU, Zhe-man XIAO
doaj
Degenerin sites mediate proton activation of deltabetagamma-epithelial sodium channel.
The Journal of biological chemistry, 2004 The delta-subunit of epithelial Na(+) channels (ENaC) is predominately expressed in brain, heart, and pancreas. The amiloride sensitivity, Na(+) conductance, and critical domains for gating are characterized as a cross between proton-activated Na(+) channels and alpha-ENaC.
Hong-Long, Ji, Dale J, Benos
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Fundamental ResearchNeonatal hyperbilirubinemia leads to neural dysfunction, including sensorineural hearing loss. Our previous studies demonstrated that elevated bilirubin induced apoptotic pathway activation and led to cell malformation in spiral ganglion neurons of ...
Yazhi Xing +10 more
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Amiloride-sensitive Na channels [PDF]
, 1998 The emerging epithelial Na channel/degenerin family of sodium channels is rapidly expanding, in particular with new members expressed in mammalian neurons and potentially involved in pain transmission.
Jean-Daniel Horisberger +1 more
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Extracellular Proteins Organize the Mechanosensory Channel Complex in C. elegans Touch Receptor Neurons [PDF]
, 2004 Specialized extracellular matrix (ECM) is associated with virtually every mechanosensory system studied. C. elegans touch receptor neurons have specialized ECM and attach to the surrounding epidermis.
Hartwieg, Erika +3 more
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Neural activity and CaMKII protect mitochondria from fragmentation in aging Caenorhabditis elegans neurons [PDF]
, 2017 Decline in mitochondrial morphology and function is a hallmark of neuronal aging. Here we report that progressive mitochondrial fragmentation is a common manifestation of aging Caenorhabditis elegans neurons and body wall muscles.
Jiang, Hao-Ching;Hsu, Jiun-Min;Yen, Chien-Ping;Chao, Chi-Chao;Chen, Ruey-Hwa;Pan, Chun-Liang +1 more
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