<i>Exploring PIEZO1</i> DNA methylation in infants with neurodevelopmental disorders. [PDF]
Mascheroni E +8 more
europepmc +1 more source
Piezo-type mechanosensitive ion channel component 1: a mechano-bioenergetic transducer in the tumour microenvironment. [PDF]
Zhang Y +7 more
europepmc +1 more source
Population genomics reveal multiple independent origins of pesticide resistance in the polyphagous pest, Tetranychus urticae. [PDF]
Chen L +11 more
europepmc +1 more source
Molecular determinants of desensitization in an ENaC/degenerin channel [PDF]
Epithelial Na(+) channel (ENaC)/degenerin family members are involved in mechanosensation, blood pressure control, pain sensation, and the expression of fear.
Sophie Roy +2 more
exaly +9 more sources
Regulation of Caenorhabditis elegans degenerin proteins by a putative extracellular domain [PDF]
Background: Rare, dominant mutations in the degenerin genes of Caenorhabditis elegans (deg-1, mec-4 and mec-10) cause neuronal degeneration. The extensive sequence similarity between degenerins and mammalian genes that encode subunits of the amiloride ...
Jaime García-Añoveros +1 more
exaly +5 more sources
The Nematode Degenerin UNC-105 Forms Ion Channels that Are Activated by Degeneration- or Hypercontraction-Causing Mutations [PDF]
Nematode degenerins have been implicated in touch sensitivity and other forms of mechanosensation. Certain mutations in several degenerin genes cause the swelling, vacuolation, and death of neurons, and other mutations in the muscle degenerin gene unc ...
Jaime García-Añoveros, David P Corey
exaly +5 more sources
Sensory Functions for Degenerin/Epithelial Sodium Channels (DEG/ENaC) [PDF]
All animals use a sophisticated array of receptor proteins to sense their external and internal environments. Major advances have been made in recent years in understanding the molecular and genetic bases for sensory transduction in diverse modalities, indicating that both metabotropic and ionotropic pathways are important in sensory functions. Here, I
Yehuda Ben-Shahar
exaly +5 more sources
Epithelial Sodium Channel/Degenerin Family of Ion Channels: A Variety of Functions for a Shared Structure [PDF]
The recently discovered epithelial sodium channel (ENaC)/degenerin (DEG) gene family encodes sodium channels involved in various cell functions in metazoans. Subfamilies found in invertebrates or mammals are functionally distinct.
Stephan Kellenberger, Laurent Schild
exaly +5 more sources

