A quantitative approach for defining the degradability landscape of protein degraders. [PDF]
Du W, De Boni L, Hopkins BD, Elemento O.
europepmc +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Recent advances in designing high-performance and enzymatically degradable plastics. [PDF]
Liu J, Zhou X, Uyama H, Takashima Y.
europepmc +1 more source
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
Temporal dynamics of ruminal metabolome and fermentation in response to molasses-treated Guinea grass-cowpea silage. [PDF]
Sossou APG, Yayota M.
europepmc +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Fenugreek seed meal as a partial replacement for soybean meal: Dose-dependent effects on in vitro rumen fermentation and greenhouse gas production. [PDF]
Gouda GA +6 more
europepmc +1 more source
Critical review on the degradability of endogenous decay products
Sludge disposal is one of the main cost factors in wastewater treatment. Endogenous processes produce inert materials (endogenous decay products) which contribute a large fraction of the sludge produced in activated sludge treatment.
Morgenroth, Eberhard (author) +7 more
core
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Tuning scaffold degradation with non-natural peptidomimetics to control human umbilical vein endothelial cell morphology and vessel formation. [PDF]
Halwachs KN +4 more
europepmc +1 more source

