Results 101 to 110 of about 4,051 (196)

Membrane-association of mRNA decapping factors is independent of stress in budding yeast [PDF]

, 2016
Recent evidence has suggested that the degradation of mRNA occurs on translating ribosomes or alternatively within RNA granules called P bodies, which are aggregates whose core constituents are mRNA decay proteins and RNA.
A Hunt, A van Hoof, A-C Gavin, AE Frazier, AH Becker, AS Madrid, AS Spirin, C Kilchert, CB Brachmann, CJ Beckham, CJ Decker, D Teixeira, DA Mangus, DJ Gibbings, E Vergés, GM Rubin, H Strahl, H Zhang, J Coller, J LaCava, J Schindelin, J-H Yoon, JA Boon den, JA Toretsky, JE Hesketh, JE Wilhelm, K Shahbabian, KA Burke, KJ Bandyra, KJ Holmes, KM Kuhn, L Hatfield, L Huang, L Stalder, L Stalder, LEA Holmes, M Brengues, MP Ashe, N Cougot, R Parker, S Ghaemmaghami, S Huch, S Jagannathan, S Jonas, S Kadaba, S Kroschwald, T Nissan, T Nissan, T Sweet, TJ Sweet, U Sheth, V Balagopal, V Jouannet, V Khemici, V Pelechano, W Hu, W-K Huh, X Wang, Y Lin, Y Uesono, YS Lee, Z Li   +61 more
core   +1 more source

Recent insights into the world of dual‐function bacterial sRNAs

WIREs RNA, Volume 15, Issue 1, January/February 2024.
Dual‐function sRNAs are fascinating riboregulators that act both as base‐pairing antisense RNAs and as peptide‐coding mRNAs, offering the possibility to control target function at different regulatory levels via RNA–RNA interactions as well as protein–protein interactions.
Sebastian Benjamin Schnoor, Peter Neubauer, Matthias Gimpel   +2 more
wiley   +1 more source

A structural and biochemical comparison of Ribonuclease E homologues from pathogenic bacteria highlights species-specific properties

Scientific Reports, 2019
Regulation of gene expression through processing and turnover of RNA is a key mechanism that allows bacteria to rapidly adapt to changing environmental conditions.
Charlotte E. Mardle, Thomas J. Shakespeare, Louise E. Butt, Layla R. Goddard, Darren M. Gowers, Helen S. Atkins, Helen A. Vincent, Anastasia J. Callaghan   +7 more
doaj   +1 more source

The influence of microgravity on invasive growth in Saccharomyces cerevisiae [PDF]

, 2011
This study investigates the effects of microgravity on colony growth and the morphological transition from single cells to short invasive filaments in the model eukaryotic organism Saccharomyces cerevisiae. Two-dimensional spreading of the yeast colonies
Daenen, Luk, Delvaux, Freddy R, Devreese, Bart, Nielsen, Jens, Siewers, Verena, Stassen, Catherine, van Eijsden, Rudy GE, Van Mulders, Sebastiaan E, Willaert, Ronnie   +8 more
core   +2 more sources

A comprehensive study of the interactions in the B. subtilis degradosome with special emphasis on the role of the small proteins SR1P and SR7P

Molecular Microbiology, Volume 121, Issue 1, Page 40-52, January 2024.
The RNA degradosome of B. subtilis comprises the major endoribonuclease RNase Y, RNases J1 and J2, PNPase, CshA helicase, and the glycolytic enzymes enolase and phosphofructokinase. Additionally, glyceraldehyde 3‐phosphate dehydrogenase A (GapA) is integrated under specific conditions.
Inam Ul Haq, Peter Müller, Sabine Brantl   +2 more
wiley   +1 more source

A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway [PDF]

, 2014
The pluripotency factor Lin28 blocks the expression of let-7 microRNAs (miRNAs) in undifferentiated cells during development and functions as an oncogene in a subset of cancers1.
Chang, Hao-Ming, Gregory, Richard I., Thornton, James E., Triboulet, Robinson   +3 more
core   +1 more source

Peptidase Activity of the Escherichia coli Hsp31 Chaperone [PDF]

, 2004
Hsp31, the Escherichia coli hcha gene product, is a molecular chaperone whose activity is inhibited by ATP at high temperature. Its crystal structure reveals a putative Cys184, His185, and Asp213 catalytic triad similar to that of the Pyrococcus ...
Abdallah, Jad, Abdallah, Jad, Caldas, Therese, Cha, Sun-Shin, Eckey, Viola, Kern, Renee, Kim, So Jung, Malki, Abderrahim, Mori, Hirotada, Richard, Richarme   +9 more
core   +1 more source

Protein Pulldown Assays to Monitor the Composition of the Bacterial RNA Degradosome

, 2020
The method of co-immunoprecipitation (co-IP or pulldown) enables the identification of proteins interacting in macromolecular assemblies, through the purification of a key protein by affinity chromatography using specific antibodies immobilized on a matrix.
Steven W, Hardwick, Ben F, Luisi, Marilis V, Marques   +2 more
openaire   +3 more sources

The Roles Of Rhle And Hfq In Srna-Dependent Gene Regulation [PDF]

, 2010
THE ROLES OF RHLE AND HFQ IN SRNA-DEPENDENT GENE REGULATION by ABEYKOON JAYALATH IRESHA SANDEEPANIE RATHNAYAKE DECEMBER 2010 Advisor: Dr. Andrew Feig Major: Chemistry Degree: Master of Science Bacteria are adapted to live in diverse environmental ...
Rathnayake, Abeykoon Jayalath Iresha Sandeepanie
core   +1 more source

Natural reassignment of CUU and CUA sense codons to alanine in Ashbya mitochondria [PDF]

, 2014
The discovery of diverse codon reassignment events has demonstrated that the canonical genetic code is not universal. Studying coding reassignment at the molecular level is critical for understanding genetic code evolution, and provides clues to genetic ...
Church, George M., Daoud, Rachid, Lajoie, Marc J., Lang, B. Franz, Ling, Jiqiang, Söll, Dieter   +5 more
core   +1 more source