Results 81 to 90 of about 3,184 (153)

Characterization of Components of the Staphylococcus aureus mRNA Degradosome Holoenzyme-Like Complex

, 2011
Bacterial two-hybrid analysis identified the Staphylococcus aureus RNA degradosome-like complex to include RNase J1, RNase J2, RNase Y, polynucleotide phosphorylase (PNPase), enolase, phosphofructokinase, and a DEAD box RNA ...
Christelle M. Roux, Paul M. Dunman, Jonathon P. DeMuth   +2 more
core   +1 more source

Dissection of the network of interactions that links RNA processing with glycolysis in the Bacillus subtilis degradosome

, 2012
The RNA degradosome is a multi-protein macromolecular complex that is involved in the degradation of messenger RNA in bacteria. The composition of this complex has been found to display a high degree of evolutionary divergence, which may reflect the ...
Rodrigues C, Newman JA, Hewitt L, Solovyova AS, Lewis RJ, Harwood CR   +5 more
core   +5 more sources

A structural and biochemical comparison of Ribonuclease E homologues from pathogenic bacteria highlights species-specific properties

Scientific Reports, 2019
Regulation of gene expression through processing and turnover of RNA is a key mechanism that allows bacteria to rapidly adapt to changing environmental conditions.
Charlotte E. Mardle, Thomas J. Shakespeare, Louise E. Butt, Layla R. Goddard, Darren M. Gowers, Helen S. Atkins, Helen A. Vincent, Anastasia J. Callaghan   +7 more
doaj   +1 more source

The small heat-shock proteins IbpA and IbpB reduce the stress load of recombinant Escherichia coli and delay degradation of inclusion bodies

Microbial Cell Factories, 2005
Background The permanently impaired protein folding during recombinant protein production resembles the stress encountered at extreme temperatures, under which condition the putative holding chaperones, IbpA/IbpB, play an important role. We evaluated the
Hoffmann Frank, Neubauer Peter, LeThanh Ha   +2 more
doaj   +1 more source

Analysis of the Escherichia coli RNA degradosome composition by a proteomic approach

, 2006
The RNA degradosome is a bacterial protein machine devoted to RNA degradation and processing. In Escherichia coli it is typically composed of the endoribonuclear RNase E, which also serves as a scaffold for the other components, the exoribonuclease ...
F. Briani, P. Mauri, G. Dehò, P. Tortora, L. Benazzi, F. Basilico, M.E. Regonesi, M. Del Favero   +7 more
core   +1 more source

The RNA degradosome: life in the fast lane of adaptive molecular evolution

In Escherichia coli, the multi-enzyme RNA degradosome contributes to the global, posttranscriptional regulation of gene expression. The degradosome components are recognized through natively unstructured "microdomains" comprising as few as 15-40 amino ...
Carpousis, Agamemnon J, DePristo, Mark A, Marcaida, Maria Jose, Chandran, Vidya, Luisi, Ben F   +4 more
core   +1 more source

The RNA degradosome in Bacillus subtilis: identification of CshA as the major RNA helicase in the multiprotein complex

, 2010
P>In most organisms, dedicated multiprotein complexes, called exosome or RNA degradosome, carry out RNA degradation and processing. In addition to varying exoribonucleases or endoribonucleases, most of these complexes contain a RNA helicase.
Henrike Pförtner, Christina Herzberg, Lehnik-Habrink, Martin, Nico Pietack, Pfoertner, Henrike, Pietack, Nico, Martin Lehnik-Habrink, Jörg Stülke, Leonie Rempeters, Herzberg, Christina, Rempeters, Leonie, Stuelke, Joerg   +11 more
core   +1 more source

Annotation of Genes for RNA Degradosome Complex in Kytococcus sedentarius

, 2013
Biology | Biotechnology | Environmental Sciences Poster PresentationIt has been reported that the microorganism responsible for causing pitted keratolysis is Kytococcus sedentarius. This aerobic, gram-positive bacterium secretes two serine proteases that
Sandhu, Praneet Kaur
core  

Association of the Cold Shock DEAD-Box RNA Helicase RhlE to the RNA Degradosome in Caulobacter crescentus

, 2017
In diverse bacterial lineages, multienzyme assemblies have evolved that are central elements of RNA metabolism and RNA-mediated regulation. The aquatic Gram-negative bacterium Caulobacter crescentus , which has been a model system
Alexandre M. Vicente, Ben F. Luisi, Steven W. Hardwick, Daniela M. Alvelos, Ricardo R. Mazzon, Angel A. Aguirre, Marilis V. Marques   +6 more
core   +1 more source

Structural and functional characterisation of the protein-protein and protein-RNA interactions in the RNA degradosome

, 2006
The C-terminal domain of RNase E is intrinsically unstructured, but small segments of 13 to 80 residues are predicted to have propensity for defined conformation and evidence presented here indicates that they function in nucleic acid binding and protein-
Chandran, V
core