eLife, 2016 In all domains of life, the catalysed degradation of RNA facilitates rapid adaptation to changing environmental conditions, while destruction of foreign RNA is an important mechanism to prevent host infection.
An Van den Bossche +11 more
doaj +1 more source
Microbiology Spectrum, 2023 The bacterium Bacillus subtilis is of high importance both as a model organism for Gram-positive bacteria and as an industrial workhorse in the production of biomolecules.
Jonathan Walgraeve +6 more
doaj +1 more source
The Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like Episode Syndrome-associated Human Mitochondrial tRNALeu(UUR) Mutation Causes Aminoacylation Deficiency and Concomitant Reduced Association of mRNA with Ribosomes [PDF]
, 2000 The pathogenetic mechanism of the mitochondrial tRNALeu(UUR) A3243G transition associated with the mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome has been investigated in transmitochondrial cell lines ...
Attardi, Giuseppe +4 more
core +1 more source
The DNA damage response acts as a safeguardagainst harmful DNA–RNA hybrids ofdifferent origins [PDF]
, 2019 Despite playing physiological roles in specific situations, DNA–RNA hybrids threat genome integrity. To investigate how cells do counteract spontaneous DNA–RNA hybrids, here we screen an siRNA library covering 240 human DNA damage response (DDR) genes ...
Aguilera López, Andrés +5 more
core +1 more source
Global analysis of Escherichia coli RNA degradosome function using DNA microarrays [PDF]
Proceedings of the National Academy of Sciences, 2004 RNase E, an essential endoribonuclease of Escherichia coli , interacts through its C-terminal region with multiple other proteins to form a complex termed the RNA degradosome. To investigate the degradosome's proposed role as an RNA decay machine, we used DNA microarrays to globally assess alterations in the steady ...
Jonathan A, Bernstein +3 more
openaire +2 more sources
BMC Microbiology, 2012 Background Transition from planktonic cells to biofilm is mediated by production of adhesion factors, such as extracellular polysaccharides (EPS), and modulated by complex regulatory networks that, in addition to controlling production of adhesion ...
Carzaniga Thomas +4 more
doaj +1 more source
Formation of a stable RNase Y-RicT (YaaT) complex requires RicA (YmcA) and RicF (YlbF)
mBio, 2023 In Bacillus subtilis, the RicT (YaaT), RicA (YmcA), and RicF (YlbF) proteins, which form a stable ternary complex, are needed together with RNase Y (Rny) to cleave and thereby stabilize several key transcripts encoding enzymes of intermediary metabolism.
Eugenie Dubnau +2 more
doaj +1 more source
Genome-Wide Study of mRNA Degradation and Transcript Elongation in Escherichia coli [PDF]
, 2015 An essential part of gene expression is the coordination of RNA synthesis and degradation, which occurs in the same cellular compartment in bacteria.
Chen, Huiyi +3 more
core +2 more sources
Identifying Subcellular Structure Components in Escherichia Coli by Crosslinking and SEC‐MS
PROTEOMICS, Volume 26, Issue 5, Page 27-36, May 2026.ABSTRACT Cells are comprised of a broad spectrum of structures that compartmentalize biochemical and signaling mechanisms. These structures can be comprised of many biomolecules, but especially lipids, proteins, and nucleic acids. Techniques are limited to quantify or discover new subcellular structures.
Rachel A. Victor +3 more
wiley +1 more source
Riboregulation in the Major Gastric Pathogen Helicobacter pylori
Frontiers in Microbiology, 2021 Helicobacter pylori is a Gram-negative bacterial pathogen that colonizes the stomach of about half of the human population worldwide. Infection by H.
Alejandro Tejada-Arranz +2 more
doaj +1 more source