Results 51 to 60 of about 4,051 (196)

An effort to make sense of antisense transcription in bacteria [PDF]

, 2012
Analysis of bacterial transcriptomes have shown the existence of a genome-wide process of overlapping transcription due to the presence of antisense RNAs, as well as mRNAs that overlapped in their entire length or in some portion of the 5'- and 3'-UTR ...
Gingeras, T. R., Lasa, I., Toledo-Arana, A.   +2 more
core   +1 more source

Unraveling new roles for minor components of the E. coli RNA degradosome [PDF]

RNA Biology, 2009
Endoribonuclease E, 3'-5' exoribonuclease polynucleotide phosphorylase, RhlB RNA helicase and enolase form a multienzyme complex (the "degradosome") playing an important role in RNA processing and decay in Escherichia coli. Although a number of proteins that occasionally co-purify with the E.
Vladimir R, Kaberdin, Sue, Lin-Chao
openaire   +2 more sources

Interplay between bacterial 5′-NAD-RNA decapping hydrolase NudC and DEAD-box RNA helicase CsdA in stress responses

mSystems, 2023
Both prokaryotic and eukaryotic RNAs can be 5′-capped by the metabolite nicotinamide adenine dinucleotide (NAD). Nudix hydrolases, such as bacterial NudC, specifically remove NAD-caps; however, the molecular and cellular functions of these ...
Milda Mickutė, Renatas Krasauskas, Kotryna Kvederavičiūtė, Gytė Tupikaitė, Aleksandr Osipenko, Algirdas Kaupinis, Monika Jazdauskaitė, Raminta Mineikaitė, Mindaugas Valius, Viktoras Masevičius, Giedrius Vilkaitis   +10 more
doaj   +1 more source

The protein tyrosine kinases EpsB and PtkA differentially affect biofilm formation in Bacillus subtilis [PDF]

, 2014
The Gram-positive soil bacterium Bacillus subtilis is able to choose between motile and sessile lifestyles. The sessile way of life, also referred to as biofilm, depends on the formation of an extracellular polysaccharide matrix and some extracellular ...
Jan Gerwig, Jörg Stülke, Katrin Gunka, Kunst, Lehnik-Habrink, Nicola Stanley-Wall, Sambrook, Taryn B. Kiley, Yasbin   +8 more
core   +3 more sources

Biophysical characterization of the Escherichia coli RNA degradosome

, 2022
In Escherichia coli, post-transcriptional regulation is a tightly controlled process facilitated by a multi-enzyme complex, the RNA degradosome. The core components of the RNA degradosome consist of the endoribonuclease RNase E, the DEAD-box helicase RhlB, the glycolytic enzyme enolase, and the exoribonuclease PNPase. The main scaffold component of the
openaire   +1 more source

Structural analysis of mtEXO mitochondrial RNA degradosome reveals tight coupling of nuclease and helicase components

Nature Communications, 2018
The mitochondrial RNA degradosome (mtEXO) plays an essential role in the regulation of mitochondrial gene expression and is composed of the 3′-to-5′ exoribonuclease Dss1 and the helicase Suv3.
Michal Razew, Zbigniew Warkocki, Michal Taube, Adam Kolondra, Mariusz Czarnocki-Cieciura, Elzbieta Nowak, Karolina Labedzka-Dmoch, Aleksandra Kawinska, Jakub Piatkowski, Pawel Golik, Maciej Kozak, Andrzej Dziembowski, Marcin Nowotny   +12 more
doaj   +1 more source

RNA chaperones buffer deleterious mutations in E. coli [PDF]

, 2015
International ...
Bae, Barrick, Bhaskaran, Bogumil, Bradford, Burga, Collins, Death, Downs, Elles, Fares, Hartl, Herschlag, Hilier, Hunger, Jarmoskaite, Jiang, Khemici, Lenski, Lenski, Lind, Lorenz, Mohr, Pan, Plotkin, Py, Queitsch, Quinlan, Rohner, Russell, Rutherford, Sawitzke, Sniegowski, Tenaillon, Tokuriki, Turner, Vallenet, Vanzo, Warnecke, Williams   +39 more
core   +2 more sources

A Mitochondria-Specific Isoform of FASTK Is Present In Mitochondrial RNA Granules and Regulates Gene Expression and Function

Cell Reports, 2015
The mitochondrial genome relies heavily on post-transcriptional events for its proper expression, and misregulation of this process can cause mitochondrial genetic diseases in humans.
Alexis A. Jourdain, Mirko Koppen, Christopher D. Rodley, Kinsey Maundrell, Naïg Gueguen, Pascal Reynier, Adela M. Guaras, José A. Enriquez, Paul Anderson, Maria Simarro, Jean-Claude Martinou   +10 more
doaj   +1 more source

Small Open Reading Frames, Non-Coding RNAs and Repetitive Elements in Bradyrhizobium japonicum USDA 110 [PDF]

, 2016
Small open reading frames (sORFs) and genes for non-coding RNAs are poorly investigated components of most genomes. Our analysis of 1391 ORFs recently annotated in the soybean symbiont Bradyrhizobium japonicum USDA 110 revealed that 78% of them contain ...
Cuklina, Jelena, Evguenieva-Hackenberg, Elena, Gelfand, Mikhail S., Hahn, Julia, Thalmann, Sebastian, Tsoy, Olga V.   +5 more
core   +2 more sources

Controlling the mitochondrial antisense – role of the SUV3-PNPase complex and its co-factor GRSF1 in mitochondrial RNA surveillance

Molecular & Cellular Oncology, 2018
Transcription of the human mitochondrial genome produces a vast amount of non-coding antisense RNAs. These RNA species can form G-quadraplexes (G4), which affect their decay. We found that the mitochondrial degradosome, a complex of RNA helicase SUPV3L1 (
Zbigniew Pietras, Magdalena A. Wojcik, Lukasz S. Borowski, Maciej Szewczyk, Tomasz M. Kulinski, Dominik Cysewski, Piotr P. Stepien, Andrzej Dziembowski, Roman J. Szczesny   +8 more
doaj   +1 more source