Results 51 to 60 of about 3,184 (153)

Characterization of RNA degradosome from E. coli with mutant polynucleotide phosphorylase

, 2006
The RNA degradosome is a bacterial protein machine devoted to RNA turnover. Degradosomes and related complexes have been described in Escherichia coli and other prokaryotes as well as in eukaryotes. The integral components of the E.
F. Briani, E. Mazzantini, G. Dehò, P. Tortora, M. Del Favero   +4 more
core   +4 more sources

The RNA processing enzyme polynucleotide phosphorylase negatively controls biofilm formation by repressing poly-N-acetylglucosamine (PNAG) production in Escherichia coli C

BMC Microbiology, 2012
Background Transition from planktonic cells to biofilm is mediated by production of adhesion factors, such as extracellular polysaccharides (EPS), and modulated by complex regulatory networks that, in addition to controlling production of adhesion ...
Carzaniga Thomas, Antoniani Davide, Dehò Gianni, Briani Federica, Landini Paolo   +4 more
doaj   +1 more source

Reconstitution and analysis of the multienzyme Escherichia coli RNA degradosome.

, 2008
The Escherichia coli RNA degradosome is a multienzyme assembly that functions in transcript turnover and maturation of structured RNA precursors. We have developed a procedure to reconstitute the RNA degradosome from recombinant components using modular ...
Górna, M, Crump, NT, Worrall, Jonathan AR, Tuck, Alex C, Górna, Maria, Crump, Nicholas T, Worrall, JA, Price, AJ, Luisi, BF, Phillips, LG, Phillips, Lara G, Bavro, Vassiliy N, Price, Amanda J, Tuck, AC, Bavro, Vass, Luisi, Ben F   +15 more
core   +1 more source

Formation of a stable RNase Y-RicT (YaaT) complex requires RicA (YmcA) and RicF (YlbF)

mBio, 2023
In Bacillus subtilis, the RicT (YaaT), RicA (YmcA), and RicF (YlbF) proteins, which form a stable ternary complex, are needed together with RNase Y (Rny) to cleave and thereby stabilize several key transcripts encoding enzymes of intermediary metabolism.
Eugenie Dubnau, Micaela DeSantis, David Dubnau   +2 more
doaj   +1 more source

Impact of pseudouridylation, substrate fold, and degradosome organization on the endonuclease activity of RNase E. [PDF]

, 2021
The conserved endoribonuclease RNase E dominates the dynamic landscape of RNA metabolism and underpins control mediated by small regulatory RNAs in diverse bacterial species.

core   +2 more sources

The FsrA‐Mediated Iron‐Sparing Response Regulates the Biosynthesis of the Epipeptide EPE in Bacillus subtilis

Molecular Microbiology, Volume 125, Issue 2, Page 108-122, February 2026.
Under iron‐limited conditions, FsrA base‐pairs with the intergenic region between epeX and epeE, enhancing epeE translation and triggering EPE production. Toxin‐mediated cell lysis releases nutrients, including iron, which can be taken up by surviving cells.
Sarah Miercke, Rabea Ghandour, Kai Papenfort, Thorsten Mascher   +3 more
wiley   +1 more source

Riboregulation in the Major Gastric Pathogen Helicobacter pylori

Frontiers in Microbiology, 2021
Helicobacter pylori is a Gram-negative bacterial pathogen that colonizes the stomach of about half of the human population worldwide. Infection by H.
Alejandro Tejada-Arranz, Alejandro Tejada-Arranz, Hilde De Reuse   +2 more
doaj   +1 more source

Metabolic Origin, Role and Fate of the Denaturant Guanidine

Microbial Biotechnology, Volume 18, Issue 11, November 2025.
The origin of metabolic guanidine is largely a mystery. We suggest it is created when guanine‐containing nucleotides are oxidised by molecular oxygen instead of being broken down into urea as purines normally would. Guanidine may act as a signal to help cells control the level of reactive oxygen species.
Antoine Danchin, Victor de Lorenzo, Pablo Iván Nikel, Conghui You   +3 more
wiley   +1 more source

From conformational chaos to robust regulation: the structure and function of the multi-enzyme RNA degradosome

, 2011
The RNA degradosome is a massive multi-enzyme assembly that occupies a nexus in RNA metabolism and post-transcriptional control of gene expression inEscherichia coliand many other bacteria.
Agamemnon J. Carpousis, Maria W. Górna, Ben F. Luisi   +2 more
core   +1 more source

Spatial organization shapes the turnover of a bacterial transcriptome

eLife, 2016
Spatial organization of the transcriptome has emerged as a powerful means for regulating the post-transcriptional fate of RNA in eukaryotes; however, whether prokaryotes use RNA spatial organization as a mechanism for post-transcriptional regulation ...
Jeffrey R Moffitt, Shristi Pandey, Alistair N Boettiger, Siyuan Wang, Xiaowei Zhuang   +4 more
doaj   +1 more source