Results 71 to 80 of about 4,051 (196)
Under iron‐limited conditions, FsrA base‐pairs with the intergenic region between epeX and epeE, enhancing epeE translation and triggering EPE production. Toxin‐mediated cell lysis releases nutrients, including iron, which can be taken up by surviving cells.
Sarah Miercke +3 more
wiley +1 more source
Spatial organization shapes the turnover of a bacterial transcriptome
Spatial organization of the transcriptome has emerged as a powerful means for regulating the post-transcriptional fate of RNA in eukaryotes; however, whether prokaryotes use RNA spatial organization as a mechanism for post-transcriptional regulation ...
Jeffrey R Moffitt +4 more
doaj +1 more source
Simulating bacterial transcription and translation in a stochastic pi-calculus [PDF]
International audienceStochastic simulation of genetic networks based on models in the stochastic pi-calculus is a promising recent approach. This paper contributes an extensible model of the central mechanisms of gene ex- pression i.e. transcription and
Kuttler, Celine
core +1 more source
Metabolic Origin, Role and Fate of the Denaturant Guanidine
The origin of metabolic guanidine is largely a mystery. We suggest it is created when guanine‐containing nucleotides are oxidised by molecular oxygen instead of being broken down into urea as purines normally would. Guanidine may act as a signal to help cells control the level of reactive oxygen species.
Antoine Danchin +3 more
wiley +1 more source
Characterization of Components of the Staphylococcus aureus mRNA Degradosome Holoenzyme-Like Complex [PDF]
ABSTRACTBacterial two-hybrid analysis identified theStaphylococcus aureusRNA degradosome-like complex to include RNase J1, RNase J2, RNase Y, polynucleotide phosphorylase (PNPase), enolase, phosphofructokinase, and a DEAD box RNA helicase. Results also revealed that the recently recognized RNase RnpA interacts with theS. aureusdegradosome and that this
Christelle M, Roux +2 more
openaire +2 more sources
Background The polynucleotide phosphorylase (PNPase) is conserved among both Gram-positive and Gram-negative bacteria. As a core part of the Escherichia coli degradosome, PNPase is involved in maintaining proper RNA levels within the bacterial cell.
Daniel-Timon Spanka +2 more
doaj +1 more source
Polyphosphate granule biogenesis is temporally and functionally tied to cell cycle exit during starvation in Pseudomonas aeruginosa [PDF]
Polyphosphate (polyP) granule biogenesis is an ancient and ubiquitous starvation response in bacteria. Although the ability to make polyP is important for survival during quiescence and resistance to diverse environmental stresses, granule genesis is ...
Dieterle, Michael G. +5 more
core +1 more source
Evidence for a degradosome‐like complex in the mitochondria of Trypanosoma brucei [PDF]
MINT‐7188074: SUV3 (genbank_protein_gi:XP_844349) physically interacts (MI:0914) with DSS1 (uniprotkb:Q38EM3) by anti tag co‐immunoprecipitation (MI:0007)
Mattiacio, Jonelle L., Read, Laurie K.
openaire +2 more sources
Maturation of Polycistronic mRNAs by the Endoribonuclease RNase Y and Its Associated Y-Complex in Bacillus Subtilis [PDF]
Endonucleolytic cleavage within polycistronic mRNAs can lead to differential stability, and thus discordant abundance, among cotranscribed genes. RNase Y, the major endonuclease for mRNA decay in Bacillus subtilis, was originally identified for its ...
DeLoughery, Aaron +3 more
core +1 more source
In quiescent PECs, Eno1 binds to the 3′ UTR of CXCL12 mRNA to prevent translation. Following activation, lactate is accumulated and then mediates an increase in lysine lactylation. Eno1, a substrate in this modification, releases bound CXCL12 mRNA upon lactylation to promote translation. Meanwhile, the activity of Eno1 as a glycolytic enzyme increases,
Xu Liu +5 more
wiley +1 more source

