Results 71 to 80 of about 4,051 (196)

The FsrA‐Mediated Iron‐Sparing Response Regulates the Biosynthesis of the Epipeptide EPE in Bacillus subtilis

open access: yesMolecular Microbiology, Volume 125, Issue 2, Page 108-122, February 2026.
Under iron‐limited conditions, FsrA base‐pairs with the intergenic region between epeX and epeE, enhancing epeE translation and triggering EPE production. Toxin‐mediated cell lysis releases nutrients, including iron, which can be taken up by surviving cells.
Sarah Miercke   +3 more
wiley   +1 more source

Spatial organization shapes the turnover of a bacterial transcriptome

open access: yeseLife, 2016
Spatial organization of the transcriptome has emerged as a powerful means for regulating the post-transcriptional fate of RNA in eukaryotes; however, whether prokaryotes use RNA spatial organization as a mechanism for post-transcriptional regulation ...
Jeffrey R Moffitt   +4 more
doaj   +1 more source

Simulating bacterial transcription and translation in a stochastic pi-calculus [PDF]

open access: yes, 2006
International audienceStochastic simulation of genetic networks based on models in the stochastic pi-calculus is a promising recent approach. This paper contributes an extensible model of the central mechanisms of gene ex- pression i.e. transcription and
Kuttler, Celine
core   +1 more source

Metabolic Origin, Role and Fate of the Denaturant Guanidine

open access: yesMicrobial Biotechnology, Volume 18, Issue 11, November 2025.
The origin of metabolic guanidine is largely a mystery. We suggest it is created when guanine‐containing nucleotides are oxidised by molecular oxygen instead of being broken down into urea as purines normally would. Guanidine may act as a signal to help cells control the level of reactive oxygen species.
Antoine Danchin   +3 more
wiley   +1 more source

Characterization of Components of the Staphylococcus aureus mRNA Degradosome Holoenzyme-Like Complex [PDF]

open access: yesJournal of Bacteriology, 2011
ABSTRACTBacterial two-hybrid analysis identified theStaphylococcus aureusRNA degradosome-like complex to include RNase J1, RNase J2, RNase Y, polynucleotide phosphorylase (PNPase), enolase, phosphofructokinase, and a DEAD box RNA helicase. Results also revealed that the recently recognized RNase RnpA interacts with theS. aureusdegradosome and that this
Christelle M, Roux   +2 more
openaire   +2 more sources

Impact of PNPase on the transcriptome of Rhodobacter sphaeroides and its cooperation with RNase III and RNase E

open access: yesBMC Genomics, 2021
Background The polynucleotide phosphorylase (PNPase) is conserved among both Gram-positive and Gram-negative bacteria. As a core part of the Escherichia coli degradosome, PNPase is involved in maintaining proper RNA levels within the bacterial cell.
Daniel-Timon Spanka   +2 more
doaj   +1 more source

Polyphosphate granule biogenesis is temporally and functionally tied to cell cycle exit during starvation in Pseudomonas aeruginosa [PDF]

open access: yes, 2017
Polyphosphate (polyP) granule biogenesis is an ancient and ubiquitous starvation response in bacteria. Although the ability to make polyP is important for survival during quiescence and resistance to diverse environmental stresses, granule genesis is ...
Dieterle, Michael G.   +5 more
core   +1 more source

Evidence for a degradosome‐like complex in the mitochondria of Trypanosoma brucei [PDF]

open access: yesFEBS Letters, 2009
MINT‐7188074: SUV3 (genbank_protein_gi:XP_844349) physically interacts (MI:0914) with DSS1 (uniprotkb:Q38EM3) by anti tag co‐immunoprecipitation (MI:0007)
Mattiacio, Jonelle L., Read, Laurie K.
openaire   +2 more sources

Maturation of Polycistronic mRNAs by the Endoribonuclease RNase Y and Its Associated Y-Complex in Bacillus Subtilis [PDF]

open access: yes, 2018
Endonucleolytic cleavage within polycistronic mRNAs can lead to differential stability, and thus discordant abundance, among cotranscribed genes. RNase Y, the major endonuclease for mRNA decay in Bacillus subtilis, was originally identified for its ...
DeLoughery, Aaron   +3 more
core   +1 more source

Global Lactylome Reveals Lactylation‐Dependent Mechanisms Underlying CXC Motif Chemokine Ligand 12 Expression in Pulmonary Endothelium During Acute Respiratory Distress Syndrome

open access: yesMedComm, Volume 6, Issue 9, September 2025.
In quiescent PECs, Eno1 binds to the 3′ UTR of CXCL12 mRNA to prevent translation. Following activation, lactate is accumulated and then mediates an increase in lysine lactylation. Eno1, a substrate in this modification, releases bound CXCL12 mRNA upon lactylation to promote translation. Meanwhile, the activity of Eno1 as a glycolytic enzyme increases,
Xu Liu   +5 more
wiley   +1 more source

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