Results 31 to 40 of about 3,184 (153)

Structural Insights into the Dimeric Form of Bacillus subtilis RNase Y Using NMR and AlphaFold

Biomolecules, 2022
RNase Y is a crucial component of genetic translation, acting as the key enzyme initiating mRNA decay in many Gram-positive bacteria. The N-terminal domain of Bacillus subtilis RNase Y (Nter-BsRNaseY) is thought to interact with various protein partners ...
Nelly Morellet, Pierre Hardouin, Nadine Assrir, Carine van Heijenoort, Béatrice Golinelli-Pimpaneau   +4 more
doaj   +1 more source

Towards Understanding Helicase and Chaperone Activities in the RNA Degradosome [PDF]

, 2020
The E. coli RNA degradosome is a complex multi-enzyme machine which is central to the post-transcriptional regulation of the cell. Some of its functions include maturing and processing sRNA, rRNA, and tRNA, as well as degrading mRNA.

core   +2 more sources

Evidence for a degradosome-like complex in the mitochondria of Trypanosoma brucei [PDF]

, 2009
Mitochondrial RNA turnover in yeast involves the degradosome, composed of DSS-1 exoribonuclease and SUV3 RNA helicase. Here, we describe a degradosome-like complex, containing SUV3 and DSS-1 homologues, in the early branching protozoan, Trypanosoma ...
Read, Laurie K., Mattiacio, Jonelle L., Laurie K Read, Jonelle L Mattiacio   +3 more
core   +1 more source

Quality control of ribosome assembly by the membrane-attached RNA degradosome.

, 2023
Cartoon depicting the synthesis of rRNA in the nucleoid, the release of early intermediates in ribosome assembly from nucleoid, maturation of late intermediates in the cytoplasm, and trimming of 17S and 9S rRNA by the membrane-attached RNA degradosome ...
Odile Burlet-Schlitz (14334426), Laurence Girbal (389237), Carine Froment (848571), Lina Hamouche (14334429), Lydia Hadjeras (13235616), Muriel Cocaign-Bousquet (255722), Agamemnon J. Carpousis (14334432), Leonora Poljak (688989), Isabelle Canal (14334420), Quentin Morin-Ogier (14334423), Marie Bouvier (260008)   +10 more
core   +1 more source

Genes important for catalase activity in Enterococcus faecalis. [PDF]

PLoS ONE, 2012
Little in general is known about how heme proteins are assembled from their constituents in cells. The Gram-positive bacterium Enterococcus faecalis cannot synthesize heme and does not depend on it for growth.
Michael Baureder, Lars Hederstedt
doaj   +1 more source

Inflammatory mitochondrial nucleic acids as drivers of pathophysiology

, 2023
Clinical and Translational Medicine, Volume 13, Issue 9, September 2023.
Christian G. Peace, Alexander Hooftman, Dylan G. Ryan   +2 more
wiley   +1 more source

Critical roles for ‘housekeeping’ nucleases in type III CRISPR-Cas immunity

eLife, 2022
CRISPR-Cas systems are a family of adaptive immune systems that use small CRISPR RNAs (crRNAs) and CRISPR-associated (Cas) nucleases to protect prokaryotes from invading plasmids and viruses (i.e., phages).
Lucy Chou-Zheng, Asma Hatoum-Aslan
doaj   +1 more source

The Sole DEAD-Box RNA Helicase of the Gastric Pathogen Helicobacter pylori Is Essential for Colonization

mBio, 2018
Present in every kingdom of life, generally in multiple copies, DEAD-box RNA helicases are specialized enzymes that unwind RNA secondary structures. They play major roles in mRNA decay, ribosome biogenesis, and adaptation to cold temperatures.
Lamya El Mortaji, Sylvie Aubert, Eloïse Galtier, Christine Schmitt, Karine Anger, Yulia Redko, Yves Quentin, Hilde De Reuse   +7 more
doaj   +1 more source

Studies of the RNA Degradosome-organizing Domain of the Escherichia coli Ribonuclease RNase E. [PDF]

, 2004
The hydrolytic endoribonuclease RNase E, which is widely distributed in bacteria and plants, plays key roles in mRNA degradation and RNA processing in Escherichia coli.
Ilag, LL, Kuhnel K, Aurikko, J., Callaghan, AJ, Symmons, MF, Callaghan AJ, Symmons M, Symmons, M., Luisi, B., Robinson, CV, Carpousis, A., Robinson, Carol V., Aurikko J, Gunter Grossmann, J., Poljak, L, Ilag, L., Ilag L, Luisi B, Aurikko, JP, Kühnel, K, Luisi, BF, Poljak, L., Illag, L., Carpousis A, Grossmann G, Poljak L, Carpousis, AJ, Callaghan, Anastasia, Chandran, V, Günter Grossmann, J, Grossmann, G., Robinson C, Callaghan, A., Kuhnel, K., Chandran V, Chandran, V., Robinson, C.   +36 more
core   +1 more source

Structural analysis of mtEXO mitochondrial RNA degradosome reveals tight coupling of nuclease and helicase components

Nature Communications, 2018
The mitochondrial RNA degradosome (mtEXO) plays an essential role in the regulation of mitochondrial gene expression and is composed of the 3′-to-5′ exoribonuclease Dss1 and the helicase Suv3.
Michal Razew, Zbigniew Warkocki, Michal Taube, Adam Kolondra, Mariusz Czarnocki-Cieciura, Elzbieta Nowak, Karolina Labedzka-Dmoch, Aleksandra Kawinska, Jakub Piatkowski, Pawel Golik, Maciej Kozak, Andrzej Dziembowski, Marcin Nowotny   +12 more
doaj   +1 more source