Results 31 to 40 of about 4,051 (196)

RNA components of Escherichia coli degradosome: Evidence for rRNA decay [PDF]

Proceedings of the National Academy of Sciences, 1998
Recently, we found that a multicomponent ribonucleolytic degradosome complex formed around RNase E, a key mRNA-degrading and 9S RNA-processing enzyme, contains RNA in addition to its protein components. Herein we show that the RNA found in the degradosome consists primarily of rRNA fragments that have a range of distinctive sizes.
Bessarab, DA, Kaberdin, VR, Wei, CL, Liou, GG, Lin-Chao, S   +4 more
openaire   +2 more sources

Adjacent single-stranded regions mediate processing of tRNA precursors by RNase E direct entry [PDF]

, 2014
The RNase E family is renowned for being central to the processing and decay of all types of RNA in many species of bacteria, as well as providing the first examples of endonucleases that can recognize 50 -monophosphorylated ends thereby increasing
Andrade, Apirion, Baker, Bandyra, Belasco, Berg, Bouvet, Breter, Bricker, Callaghan, Callaghan, Carpousis, Celesnik, Chen, Coburn, Danchin, David Romero A., Deana, Dong, Emory, Garrey, Garrey, Ghora, Gopel, Hartmann, Jane A. Grasby, Jiang, Jourdan, Jourdan, Justin E. Clarke, Kaberdin, Kaberdin, Kaberdin, Kaga, Kenneth J. McDowall, Kido, Kime, Kime, Koslover, Lee, Leroy, Li, Li, Li, Li, Lin-Chao, Louise Kime, Lundberg, Mackie, Mackie, Mackie, Mackie, McDowall, McDowall, McDowall, McDowall, Misra, Mohanty, Mohanty, Ono, Ow, Perwez, Redko, Taraseviciene, Tock, Umitsuki, Wachi, Walsh   +67 more
core   +2 more sources

Editosome Accessory Factors KREPB9 and KREPB10 in Trypanosoma brucei [PDF]

, 2012
Multiprotein complexes, called editosomes, catalyze the uridine insertion and deletion RNA editing that forms translatable mitochondrial mRNAs in kinetoplastid parasites.
Acestor, Achim Schnaufer, Alatortsev, Ammerman, Aphasizheva, Aphasizheva, Bailey, Borst, Carnes, Carnes, Carnes, Cruz-Reyes, Cruz-Reyes, Deschamps, Ernst, Ernst, Etheridge, Fisk, Guo, Guo, Guo, Hashimi, Igo, Igo, Inoue, Jason Carnes, Jensen, Kao, Kenneth Stuart, Koslowsky, Koslowsky, Lukes, Mattiacio, Mattiacio, Melissa Lerch, Militello, Nathalie Acestor, Niemann, Panigrahi, Panigrahi, Panigrahi, Panigrahi, Panigrahi, Panigrahi, Piller, Rigaut, Ryan, Sabatini, Schnaufer, Schnaufer, Seiwert, Simpson, Stuart, Trotter, Weng, Wirtz, Worthey, Xuemin Guo, Zhang   +58 more
core   +1 more source

A eukaryotic-like 3′ untranslated region in Salmonella enterica hilD mRNA [PDF]

, 2014
Long 3' untranslated regions (3'UTRs) are common in eukaryotic mRNAs. In contrast, long 3'UTRs are rare in bacteria, and have not been characterized in detail.
Casadesús Pursals, Josep, López Garrido, Javier, Puerta Fernández, Elena   +2 more
core   +1 more source

Structural insights into RNase J that plays an essential role in Mycobacterium tuberculosis RNA metabolism

Nature Communications, 2023
Ribonucleases (RNases) are responsible for RNA metabolism. RNase J, the core enzyme of the RNA degradosome, plays an essential role in global mRNA decay.
Luyao Bao, Juan Hu, Bowen Zhan, Mingzhe Chi, Zhengyang Li, Sen Wang, Chan Shan, Zhaozhao Zhao, Yanchao Guo, Xiaoming Ding, Chaoneng Ji, Shengce Tao, Ting Ni, Xuelian Zhang, Guoping Zhao, Jixi Li   +15 more
doaj   +1 more source

Allosteric activation of RhlB by RNase E induces partial duplex opening in substrate RNA

Frontiers in Molecular Biosciences, 2023
The E. coli DEAD-Box helicase RhlB is responsible for ATP-dependent unwinding of structured mRNA to facilitate RNA degradation by the protein complex degradosome.
Heidi Zetzsche, Laura Raschke, Boris Fürtig   +2 more
doaj   +1 more source

Examining the Protein Interactome and Subcellular Localization of RNase J2 Complexes in Streptococcus mutans

Frontiers in Microbiology, 2019
Regulated RNA turnover is vital for the control of gene expression in all cellular life. In Escherichia coli, this process is largely controlled by a stable degradosome complex containing RNase E and a variety of additional enzymes.
Rong Mu, Pushkar Shinde, Zhengzhong Zou, Jens Kreth, Jens Kreth, Justin Merritt, Justin Merritt   +6 more
doaj   +1 more source

Structural Insights into the Dimeric Form of Bacillus subtilis RNase Y Using NMR and AlphaFold

Biomolecules, 2022
RNase Y is a crucial component of genetic translation, acting as the key enzyme initiating mRNA decay in many Gram-positive bacteria. The N-terminal domain of Bacillus subtilis RNase Y (Nter-BsRNaseY) is thought to interact with various protein partners ...
Nelly Morellet, Pierre Hardouin, Nadine Assrir, Carine van Heijenoort, Béatrice Golinelli-Pimpaneau   +4 more
doaj   +1 more source

Polyphosphate - an ancient energy source and active metabolic regulator [PDF]

, 2011
There are a several molecules on Earth that effectively store energy within their covalent bonds, and one of these energy-rich molecules is polyphosphate.
Lucia Achbergerová, Jozef Nahálka
core   +1 more source

Genes important for catalase activity in Enterococcus faecalis. [PDF]

PLoS ONE, 2012
Little in general is known about how heme proteins are assembled from their constituents in cells. The Gram-positive bacterium Enterococcus faecalis cannot synthesize heme and does not depend on it for growth.
Michael Baureder, Lars Hederstedt
doaj   +1 more source