Results 21 to 30 of about 3,184 (153)
Frontiers in Cellular and Infection Microbiology, 2013 Microbes are incessantly challenged by both biotic and abiotic stressors threatening their existence. Therefore, bacterial pathogens must possess mechanisms to successfully subvert host immune defenses as well as overcome the stress associated with host ...
Jason A. Rosenzweig, Ashok K Chopra
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Distinct co-evolution patterns of genes associated to DNA polymerase III DnaE and PolC
BMC Genomics, 2012 Background Bacterial genomes displaying a strong bias between the leading and the lagging strand of DNA replication encode two DNA polymerases III, DnaE and PolC, rather than a single one.
Engelen Stefan +3 more
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A type III-A CRISPR-Cas system employs degradosome nucleases to ensure robust immunity
eLife, 2019 CRISPR-Cas systems provide sequence-specific immunity against phages and mobile genetic elements using CRISPR-associated nucleases guided by short CRISPR RNAs (crRNAs).
Lucy Chou-Zheng, Asma Hatoum-Aslan
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Localization of components of the RNA-degrading machine in Bacillus subtilis
Frontiers in Microbiology, 2016 In bacteria, the control of mRNA stability is crucial to allow rapid adaptation to changing conditions. In most bacteria, RNA degradation is catalyzed by the RNA degradosome, a protein complex composed of endo- and exoribonucleases, RNA helicases and ...
Nora Cascante-Estepa +2 more
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The BR-body proteome contains a complex network of protein-protein and protein-RNA interactions
Cell Reports, 2023 Summary: Bacterial ribonucleoprotein bodies (BR-bodies) are non-membrane-bound structures that facilitate mRNA decay by concentrating mRNA substrates with RNase E and the associated RNA degradosome machinery.
Vidhyadhar Nandana +16 more
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Analysis of the RNA degradosome complex from a Marine Vibrio species [PDF]
, 2010 The RNA degradosome is a conglomerate of proteins responsible for the degradation of most mRNA transcripts in the prokaryotic cell. The present work was motivated by the need to better understand whether the RNA degradosome in Vibrio angustum S14 is ...
Erce, Melissa Angelica
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Frontiers in Microbiology, 2019 Regulated RNA turnover is vital for the control of gene expression in all cellular life. In Escherichia coli, this process is largely controlled by a stable degradosome complex containing RNase E and a variety of additional enzymes.
Rong Mu +6 more
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Nature Communications, 2023 Ribonucleases (RNases) are responsible for RNA metabolism. RNase J, the core enzyme of the RNA degradosome, plays an essential role in global mRNA decay.
Luyao Bao +15 more
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Allosteric activation of RhlB by RNase E induces partial duplex opening in substrate RNA
Frontiers in Molecular Biosciences, 2023 The E. coli DEAD-Box helicase RhlB is responsible for ATP-dependent unwinding of structured mRNA to facilitate RNA degradation by the protein complex degradosome.
Heidi Zetzsche +2 more
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The E.coli RNA degradosome analysis of molecular chaperones and enolase [PDF]
, 2010 Normal mRNA turnover is essential for genetic regulation within cells. The E. coli RNA degradosome, a large multi-component protein complex which originates through specific protein interactions, has been referred to as the “RNA decay machine” and is ...
Burger, Adélle
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