Results 161 to 170 of about 111,597 (294)

Efficacy of House Dust Mite Immunotherapy in Chinese Allergic Rhinitis Patients With Diverse Sensitization Patterns: A Multicenter Study (COVER Study)

Allergy, EarlyView.
This prospective multicenter study corroborates the efficacy of AIT with the native HDM allergen extract in Chinese AR patients with diverse HDM sensitization patterns. HDM sensitization pattern affects the efficacy of AIT, with patients sensitized to both major and minor allergens of HDM showing improved outcomes with HDM SCIT.
Qingxiu Xu, Xuan Yuan, Wang Liao, Hao Chen, Qing Jiang, Lin Yang, Jin Liu, Le Li, Nan Huang, Wenjing Li, Yaqi Yang, Dongxia Ma, Jun Bai, Zhihai Xie, Rongfei Zhu   +14 more
wiley   +1 more source

Discovery of Lomitapide as a Novel Mast Cell Regulatory Agent Through Chemical Library Screening. [PDF]

Eur J Immunol
Mamorita S, Furukawa A, Nagata Y, Suzuki R.   +3 more
europepmc   +1 more source

Peanut Component‐Specific IgE and IgG4 Are Modulated by Sublingual Immunotherapy and Are Associated With Remission in 1–4‐Year‐Old Children

Allergy, EarlyView.
This study presents a post hoc analysis of longitudinal changes in peanut component‐specific IgE and IgG4 in children aged 1–4 years undergoing peanut SLIT, aiming to uncover immune mechanisms and potential biomarkers of remission. Peanut SLIT reduced IgE and increased IgG4 responses to Ara h 1, Ara h 2, Ara h 3, and Ara h 6.
Neel Singh, Janelle Kesselring, Jess Humphrey, Lauren Herlihy, A. Wesley Burks, Johanna Smeekens, Corinne Keet, J. Andrew Bird, Edwin H. Kim, Michael Kulis   +9 more
wiley   +1 more source

Pluviatolide Attenuates Type I Hypersensitivity through Regulation of Mast Cell Activation. [PDF]

Biomol Ther (Seoul)
Kim SY, Park JW, Shin J, Lee JA, Leem SH, Jo MG, Choi MY, Choi WS, Min KY, Noh G, Bae SJ, Choi YH, Kim HS.   +12 more
europepmc   +1 more source

Major Cat Allergen Fel d 4: Structure and Identification of a Cross‐Reactive IgE‐Epitope‐Containing Area

Allergy, EarlyView.
This study reports the three‐dimensional structure of an important cat allergen, Fel d 4, that shares high homology with Equ c 1 (i.e., major horse allergen) and Can f 6 (i.e., dog allergen). The C‐terminal region of the Fel d 4 contains a major IgE‐reactive epitope.
Nikolina Todorović, Daria Trifonova, Zicheng Liu, Mirela Curin, Laszlo Schooltink, Theo Sagmeister, Christoph Grininger, Renata Kiss, Nina Gottstein, Bernd Gesslbauer, Andreas Winkler, Tea Pavkov‐Keller, Alexander Karaulov, Rudolf Valenta, Walter Keller   +14 more
wiley   +1 more source

Identification of Natural Compounds Triggering MRGPRX2-Mediated Calcium Flux and Degranulation in RBL-2H3 Cells. [PDF]

Cells
Zhang L, Liu J, Zheng J, Jing W, Zhang W, Chen J, Zhang X, Cheng X, Wei F.   +8 more
europepmc   +1 more source

Aging changes the mechanism that underlies JAK2 modulation of neutrophil function. [PDF]

J Immunol
Feldmann JW, Kays M, McGinnis F, Herron E, Sati N, Woods C, Coulibaly AP.   +6 more
europepmc   +1 more source

Disturbances of selected plasma proteins in Hyperdynamic Septic Shock [PDF]

, 1982
A Ledgerwood, AO Aasen, AO Aasen, CB Laurell, D Collen, DL Heene, DM Rangel, EA Friedmann, EF Gersmeyer, FW Putnam, H Fritz, H Graeff, H Schiessler, H. Fritz, HG Lasch, J Johnson, J. Witte, JW Alexander, K Havemann, K Hochstrasser, K Messmer, K Ohlsson, K. Hochstrasser, M Jochum, M Jochum, M. Jochum, MS Losowsky, N Freudenberg, P Skansberg, PJ Hamilton, PM Starkey, R Dielt, R Egbring, R Hafter, R. Scherer, RG Lerner, W Schramm, W Schramm, W. Schramm   +38 more
core   +1 more source

Mast Cell Degranulation [PDF]

, 2020
openaire   +1 more source

Oral Immunotherapy Induces Shift in lncRNA Expression Modulating Allergen‐Specific Immune Responses

Allergy, EarlyView.
We used PBMC transcriptome from 50 hen's egg‐allergic patients to study the role of lncRNA in OIT. Positive correlation was found between 17 lncRNAs and the IL‐4/IL‐13 pathway in vivo, and the expression of the selected lncRNA aligned with CXCL8 upon PBMC egg‐restimulation.
Olivia Liong, Kati Palosuo, Victoria Hinkkanen, Vittorio Fortino, Mika J. Mäkelä, Piia Karisola   +5 more
wiley   +1 more source