Results 241 to 250 of about 137,298 (386)

Targeting Inhibitory Siglec-3 to Suppress IgE-Mediated Human Basophil Degranulation

Suzanne Barshow, Md. Maidul Islam, Scott P. Commins, Matthew S. Macauley, James C. Paulson, Michael D. Kulis   +5 more
openalex   +1 more source

Assessment of Patients With Beta‐Lactams Positive Provocation Tests by Biomarkers of IgG‐Related Neutrophil Activation

Clinical &Experimental Allergy, EarlyView.
Neutrophil activation in beta‐lactams (BL) immediate hypersensitivity reactions (IHR). Factor component analysis of IHR biomarkers suggests an IgG‐mediated mechanism. We propose Neutrophil Elastase as a biomarker of neutrophil activation in BL IHR. ABSTRACT Background Beta‐lactams (BLs) are the predominant cause of immediate allergic reactions to drugs.
Adrienne Astrid Gallizzi, Rosa‐Maria Guéant‐Rodriguez, Cosmin Boteanu, Jean‐Marc Alberto, Cécile Lakomy, Huguette Louis, Celine Chery, Pauline Renard, Véronique Regnault, Ramia Safar, Almut Heinken, Antonino Romano, Jose‐Julio Laguna, Jean‐Louis Guéant   +13 more
wiley   +1 more source

Phenotypic, proteomic, and functional analyses of cytokine-induced memory-like NK cells show two distinct subsets based on CD16 expression. [PDF]

Sci Rep
Carreira-Santos S, González-Sánchez M, López-Sejas N, Hassouneh F, González-Fernández L, Jorge I, Durán E, Pera A, Vázquez J, Solana R, Tarazona R, Casado JG.   +11 more
europepmc   +1 more source

CD63 is tightly associated with intracellular, secretory events chaperoning piecemeal degranulation and compound exocytosis in human eosinophils

Journal of Leukocyte Biology, 2016
Lívia A S Carmo, Kennedy Bonjour, S. Ueki, J. S. Neves, Linying Liu, L. Spencer, A. Dvorak, P. Weller, R. C. Melo   +8 more
semanticscholar   +1 more source

Diagnosis of Periodontitis via Neutrophil Degranulation Signatures Identified by Integrated scRNA-Seq and Deep Learning. [PDF]

Genes (Basel)
Wu H, Huang L, Cai S, Xiong X, He Y.
europepmc   +1 more source

TGFβ enhances platelet–breast‐cancer‐cell interaction and promotes platelet aggregation

The FEBS Journal, EarlyView.
TGFβ stimulation promotes EMT in MCF7 cells, increasing their ability to bind, activate, and aggregate PLT. This effect involves the upregulation of adhesion molecules Integrin‐αv and Galectin‐3. Inhibiting Integrin‐αv or Galectin‐3, through Cilengitide and GB1103, reduces PLT adhesion to MCF7 and PLT aggregation, suggesting a mechanism linking TGFβ ...
Margherita Genitoni, Lucia Merolle, Agnese Razzoli, Eleonora Maurizi, Gaia Gavioli, Roberto Baricchi, Chiara Marraccini, Davide Schiroli   +7 more
wiley   +1 more source

A Novel Cell Culture System to Improve MRGPRX2 Research in Human Skin Mast Cells. [PDF]

Clin Transl Allergy
Li Z, Schneikert J, Wegner A, Zuberbier T, Babina M.   +4 more
europepmc   +1 more source

TRPM7 kinase activity regulates murine mast cell degranulation

Journal of Physiology, 2016
S. Zierler, A. Sumoza‐Toledo, Sayuri Suzuki, Fionán Ó Dúill, Lillia V. Ryazanova, R. Penner, A. Ryazanov, A. Fleig   +7 more
semanticscholar   +1 more source

Mapped! A machinery of degranulation in mast cells. Focus on “Serum- and glucocorticoid-inducible kinase SGK1 regulates reorganization of actin cytoskeleton in mast cells upon degranulation”

, 2012
Susan Z. Hua
openalex   +2 more sources

Mechanism of Peptide-induced Mast Cell Degranulation [PDF]

, 1998
Dorothea Lorenz, Burkhard Wiesner, J. Zipper, Anett Winkler, Eberhard Krause, Michael Beyermann, Manfred Lindau, Michael Bienert   +7 more
openalex   +1 more source