Results 111 to 120 of about 98,772 (389)

Characterization of drug metabolizing enzymes and assessment of aging in the gilthead seabream (Sparus aurata) liver

open access: yesVeterinární Medicína, 2010
Organic anthropogenic compounds such as polycyclic aromatic hydrocarbons, polychlorinated biphenyls, nitroaromatics, dioxins, various pesticides and natural compounds can enter the aquatic environment. These lipophilic compounds are readily taken up into
H. Ardag Akdogan, A. Sen
doaj   +1 more source

X-linked histone H3K27 demethylase Kdm6a regulates sexually dimorphic differentiation of hypothalamic neurons [PDF]

open access: hybrid, 2021
Lucas E. Cabrera Zapata   +5 more
openalex   +1 more source

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You   +12 more
wiley   +1 more source

Genome-wide identification and comparative analysis of cytosine-5 DNA methyltransferases and demethylase families in wild and cultivated peanut

open access: yesFrontiers in Plant Science, 2016
DNA methylation plays important roles in genome protection, regulation of gene expression and was associated with plants development. Plant DNA methylation pattern was mediated by cytosine-5 DNA methyltransferases and demethylase. Although the genomes of
Pengfei eWang   +9 more
doaj   +1 more source

Histone demethylase AMX-1 is necessary for proper sensitivity to interstrand crosslink DNA damage.

open access: yesPLoS Genetics, 2021
Histone methylation is dynamically regulated to shape the epigenome and adjust central nuclear processes including transcription, cell cycle control and DNA repair.
Xiaojuan Zhang   +6 more
doaj   +1 more source

Fungicide Resistance Genetics of Apple Scab fungus Venturia inaequalis [PDF]

open access: yes, 2015
Apple scab, caused by the ascomycete fungus Venturia inaequalis, is considered the most devastating disease on domestic apple crops. Apples are the most important cultivated crop in temperate regions and the United States produced about 4.6 million tons ...
Reddel, Alexis LT
core   +1 more source

Adaptive genomic structural variation in the grape powdery mildew pathogen, Erysiphe necator. [PDF]

open access: yes, 2014
BackgroundPowdery mildew, caused by the obligate biotrophic fungus Erysiphe necator, is an economically important disease of grapevines worldwide. Large quantities of fungicides are used for its control, accelerating the incidence of fungicide-resistance.
Amrine, Katherine CH   +7 more
core   +2 more sources

Diatoms synthesize sterols by inclusion of animal and fungal genes in the plant pathway [PDF]

open access: yes, 2020
Diatoms are ubiquitous microalgae that have developed remarkable metabolic plasticity and gene diversification. Here we report the first elucidation of the complete biosynthesis of sterols in the lineage.
, Angela   +7 more
core   +1 more source

Positive Feedback Loop of Histone Lactylation‐Driven HNRNPC Promotes Autophagy to Confer Pancreatic Ductal Adenocarcinoma Gemcitabine Resistance

open access: yesAdvanced Science, EarlyView.
Histone 3 lysine18 lactylation (H3K18la) drives heterogeneous nuclear ribonucleoprotein C (HNRNPC) overexpression, activating autophagy to mediate gemcitabine resistance by stabilizing TNF receptor‐associated factor 6 (TRAF6) mRNA. Concurrently, HNRNPC stabilizes aldehyde dehydrogenase 1 family member A3 (ALDH1A3) mRNA, which enhances glycolysis and ...
Xi‐Tai Huang   +9 more
wiley   +1 more source

Evidence of a Demethylase-Independent Role for the H3K4-Specific Histone Demethylases in Aspergillus nidulans and Fusarium graminearum Secondary Metabolism

open access: yesFrontiers in Microbiology, 2019
Fungi produce a plethora of secondary metabolites (SMs) involved in cellular protection, defense, and signaling. Like other metabolic processes, transcription of SM biosynthesis genes is tightly regulated to prevent an unnecessary use of resources. Genes
Simone Bachleitner   +5 more
doaj   +1 more source

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