Results 241 to 250 of about 95,899 (339)

Emerging role of <i>KDM5C</i> in X-linked intellectual disability based on human genetic data and zebrafish models. [PDF]

Front Mol Neurosci
Liao B, Chen M, Huang Y, Shuai M, Xu L, He S, Huang H.   +6 more
europepmc   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, Volume 13, Issue 14, 9 March 2026.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Novel Metabolites of <i>Xylaria thienhirunae</i> SWUF17-44.1 with Biological Activities and Molecular Docking Analysis. [PDF]

J Fungi (Basel)
Thongsuwan P, Nahar L, Sarker SD, Kongmaung P, Choowongkomon K, Phosri C, Suwannasai N.   +6 more
europepmc   +1 more source

LSD1 activates a lethal prostate cancer gene network independently of its demethylase function

Proceedings of the National Academy of Sciences of the United States of America, 2018
A. Sehrawat, Lina Gao, Yuliang Wang, A. Bankhead, S. McWeeney, Carly J. King, Jacob Schwartzman, Joshua Urrutia, William H. Bisson, Daniel J. Coleman, S. Joshi, Dae-Hwan Kim, David A. Sampson, S. Weinmann, B. Kallakury, D. Berry, R. Haque, S. K. Van Den Eeden, Sunil Sharma, Jared J. Bearss, T. Beer, G. Thomas, Laura M. Heiser, J. Alumkal   +23 more
semanticscholar   +1 more source

Lysine-Specific Demethylase 5A [PDF]

, 2020
openaire   +1 more source

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

Advanced Science, Volume 13, Issue 16, 18 March 2026.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen, Guoming Chen, Xieyuan Leng, Qianfan Li, Wenhao Wu, Wenqiu Wu, Zixuan Liu, Zilan Zhong, Xiaohong Zheng, Wei Kang, Fazheng Ren, Yigan Zhang, Juan Chen   +12 more
wiley   +1 more source

Dysregulation of ERAD and Stress Response Proteins by V493F FTO Over-expression: A Proteomic Perspective. [PDF]

In Vivo
Kanli A.
europepmc   +1 more source

No Evidence of Impact of Genetic Sex on Hyperthermia‐Induced Neural Tube Defects in Chicken Embryos

Birth Defects Research, Volume 118, Issue 3, March 2026.
ABSTRACT Background In mammals, cranial neural tube defects (NTDs) are more likely to occur in females. It has been proposed that the sex bias in NTDs was due to the presence of the inactive X chromosome in the somatic cells of female embryos and that the inactive X acted as a heterochromatic sink, competing for silencing factors with the rest of the ...
Yiting Wang, Aimee K. Ryan, Anna K. Naumova   +2 more
wiley   +1 more source

Follicle stimulating hormone stimulates farnesyl-diphosphate farnesyltransferase 1 expression through LSD1Ser54p in chicken ovarian granulosa cells. [PDF]

Poult Sci
Zhang Y, Zhang M, Liu Q, Jiang Y.
europepmc   +1 more source

CRISPR Assays for Protein Detection

Chemistry–Methods, Volume 6, Issue 3, March 2026.
This review summarizes recent advances in CRISPR–Cas–based strategies for protein detection. Particular focus is placed on recognition element–based approaches, in which antibodies, aptamers, or DNAzymes convert protein binding into CRISPR‐readable nucleic acid signals, and activity‐based strategies that exploit intrinsic protein functions to trigger ...
Luca Capelli, Elena Spezzani, Dharshini Raghavan, Chiara Micucci, Alessandra Zanut, Alessandro Bertucci   +5 more
wiley   +1 more source