Results 241 to 250 of about 98,772 (389)

Exploring the impact of microbial dysbiosis on ovarian cancer and the therapeutic potential of probiotics

VIEW, EarlyView.
Ovarian cancer has been linked to the microbiome as a potential environmental contributor, but how this association relates to tumor progression remains unclear. By comparing tumor and nontumor tissues, we identified a severity‐associated microbial and metabolic signature and showed that probiotics can partially restore immune balance and slow tumor ...
Chanyuan Li, Nalan Tu, Xin Ning, Yunyan Cong, Fei Wu, Xiuli Zhang, Runrong Li, Yue Xu, Binqiao Wang, Liqin Jin, Yuanming Shen, Jihong Liu   +11 more
wiley   +1 more source

Biological roles of LSD1 beyond its demethylase activity

Cellular and Molecular Life Sciences, 2020
Feiying Gu, Yuxin Lin, Zhun Wang, Xiaoxin Wu, Zhenyue Ye, Yuezhen Wang, Huiyin Lan   +6 more
semanticscholar   +1 more source

Lysine-Specific Demethylase 2 Suppresses Lipid Influx and Metabolism in Hepatic Cells [PDF]

, 2015
Katsuya Nagaoka, Shinjiro Hino, Akihisa Sakamoto, Kotaro Anan, Ryuta Takase, Takashi Umehara, Shigeyuki Yokoyama, Yutaka Sasaki, Mitsuyoshi Nakao   +8 more
openalex   +1 more source

In Vitro Activities of Five Antifungal Drugs Against Conidia and Sclerotic Cells of Chromoblastomycosis Agent Fonsecaea spp

Microbiology and Immunology, EarlyView.
ABSTRACT Chromoblastomycosis (CBM) is a chronic skin and subcutaneous infection mainly caused by Fonsecaea pedrosoi, a dematiaceous fungus with various morphotypes. Characteristic sclerotic cells—globe‐shaped, multiseptated and pigmented—are found in lesions of infected individuals, though their differentiation in the host remains poorly understood. To
Aline Barral Takahashi, Daniella Paternostro de Araújo Grisólia, Moises Batista da Silva, Naila Ferreira da Cruz, Sâmela Miranda da Silva, Patrícia Fagundes da Costa, Claudio Guedes Salgado   +6 more
wiley   +1 more source

Anti-tumor effects and mechanism of the histone demethylase inhibitor GSK-J4 in non-small cell lung cancer cells. [PDF]

Med Oncol
Xu D, Wang M, Wu M, Yu Y, Chen X, Wen Z, Shen D, Liu T, Chen H.   +8 more
europepmc   +1 more source

Sulfonylamido Derivatives of 2-Aminophenoxathiin-10,10-Dioxide and Related Compounds Possess Antifungal Action Due to the Possible Inhibition of Lanosterol-14-α-Demethylase [PDF]

, 1998
Claudiu T. Supuran, Andrea Scozzafava, Fabrizio Briganti, G. Loloiu, O. Maior   +4 more
openalex   +1 more source

Histone Demethylase KDM5C Deficiency Inhibits Bone Formation and Fracture Healing in Aged Mice by Epigenetically Activating Erdr1

, 2021
Ying Li, Lingli Ding, Bingyu Zhou, Bin Wang, Min Wang, Yamei Liu, Weiping Lin, Haibin Wang, Gang Li, Yonghui Hou, Liangliang Xu   +10 more
openalex   +1 more source

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

Andrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos, Marie‐Pier Scott‐Boyer, Arnaud Droit, Robert S. Viger, Jacques J. Tremblay   +4 more
wiley   +1 more source

Econazole Exhibits In Vitro and In Vivo Efficacy Against Leishmania amazonensis. [PDF]

Pharmaceuticals (Basel)
Mesquita JT, Dias IO, Tempone AG, Reimão JQ.   +3 more
europepmc   +1 more source

Histone Demethylase Expression Enhances Human Somatic Cell Nuclear Transfer Efficiency and Promotes Derivation of Pluripotent Stem Cells [PDF]

, 2015
Young Gie Chung, Shogo Matoba, Yuting Liu, Jin Hee Eum, Falong Lu, Wei Jiang, Jeoung Eun Lee, Vicken Sepilian, Kwang Yul, Dong Ryul Lee, Yi Zhang   +10 more
openalex   +1 more source