Results 141 to 150 of about 70,292 (240)

Demyelination-related pain: role of lysophosphatidic acid in satellite glial cell-neuron crosstalk. [PDF]

J Transl Med
Wang Y, Sun Q, Hanani M, Qu J, Guo X, Yang W, Shao T, Zheng S, Qiao S, Jia Y, Huang Y, Yang Y, Zhu H, Dong X, Zhou FQ, Guan Y, Song X, Chen Z.   +17 more
europepmc   +1 more source

Relapse and Neurological Prognosis in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease: A Retrospective Secondary Analysis of a Japanese Nationwide Epidemiologic Survey

Clinical and Experimental Neuroimmunology, Volume 17, Issue 2, May 2026.
ABSTRACT Background Some patients with myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) experience multiple relapses and poor prognoses; however, the factors associated with these outcomes are unclear. This study aimed to identify factors associated with relapse and neurological prognosis in patients with MOGAD.
Masashi Nakamura, Juichi Fujimori, Akiyuki Uzawa, Satoshi Kuwabara, Ichiro Nakashima   +4 more
wiley   +1 more source

Astrocyte-intrinsic signaling of chitinase-like protein CHI3L1 drives inflammation and amplifies demyelination in neuromyelitis optica. [PDF]

J Clin Invest
Xu H, Jiang W, Xu L, Li H, Yang X, Zhu F, He P, Song Y, Li Y, Huang YA, Qiu W, Tang C.   +11 more
europepmc   +1 more source

Neuronal Activity Promotes Node‐Like Cluster Assembly Prior to Myelination and Remyelination in the Central Nervous System

Glia, Volume 74, Issue 4, April 2026.
Ronzano et al. show that neuronal activity promotes node‐like cluster (NLC) formation before (re)myelination by regulating β1Nav and Nav1.1, which are essential for NLC assembly. This may represent an intermediate step in activity‐driven myelination and contribute to the regulation of axonal conduction.
Rémi Ronzano, Clément Perrot, Elisa Mazuir, Melina Thetiot, Marie‐Stéphane Aigrot, Paul Stheneur, François‐Xavier Lejeune, Bruno Stankoff, Catherine Lubetzki, Nathalie Sol‐Foulon, Anne Desmazières   +10 more
wiley   +1 more source

Effect of transplanted oligodendrocyte precursor cells derived from inflammatory and non-inflammatory microenvironment on remyelination in a chronic cuprizone model. [PDF]

PLoS One
Akbari H, Ragerdi-Kashani I, Rezaei-Yazdi F, Pasbakhsh P.   +3 more
europepmc   +1 more source

Mapping Intracellular Volume Fraction With Susceptibility Source Decomposition as a Marker for Tissue Cellularity

Journal of Magnetic Resonance Imaging, Volume 63, Issue 4, Page 1092-1105, April 2026.
ABSTRACT Background Pathophysiological changes affect tissue cell composition and density. For example, neurodegenerative disorders and brain tumors are associated with cell loss and abnormal accumulation, respectively. In these scenarios, if monitored and tracked, tissue cellularity might be used to inform clinical diagnosis and management. Purpose To
Giulia Debiasi, Oliver C. Kiersnowski, Giovanni Librizzi, Luca Roccatagliata, Renzo Manara, Mauro Costagli, Alessandra Bertoldo, Chunlei Liu   +7 more
wiley   +1 more source

Trigeminal root demyelination is sufficient to induce trigeminal neuralgia-like facial pain in adult rodents. [PDF]

J Headache Pain
Wang ZY, Ding YQ, Wen JM, Zheng BW, Zhang K, Qi JG.   +5 more
europepmc   +1 more source

Application and Challenges of Chimeric Antigen Receptor T Cell Therapy in Systemic Rheumatic Diseases and Autoimmune Disorders

MedComm, Volume 7, Issue 4, April 2026.
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley   +1 more source

Case Report: Combined central and peripheral nerve demyelination with neurofilament heavy chain antibodies. [PDF]

Front Immunol
Zhao XL, Zhao ZY, Yang CL, Xu H, Zhang M, Wang GQ, Liu Y, Li YB, Duan RS, Li XL.   +9 more
europepmc   +1 more source

Electroactive Biodegradable Nerve Conduits Based on Alginate–Gelatine Polymer Matrix Modified With Inorganic Nanoparticles

Natural Sciences, Volume 6, Issue 2, April 2026.
The effects of ZnO, fullerene C60 and polyaniline (PANI) nanoparticles in hybrid nerve conduits are explored. The composites show enhanced electrical conductivity, permeability to physiological fluids and mechanical stability. The biocompatibility of composites is confirmed by in vivo and in vitro studies.
Liudmyla Sukhodub, Mariia Kumeda, Oleksandr Tsyndrenko, Natalia Bozhko, Liudmyla Vovchenko, Volodymyr Prokopiuk, Oleksander Petrenko, Leonid Sukhodub   +7 more
wiley   +1 more source