Fasciola hepatica excretory-secretory products attenuate demyelination and reduce neuroinflammation in the Cuprizone -induced multiple sclerosis model. [PDF]
Mariki A +6 more
europepmc +1 more source
Histiocytosis development and clinical variation through the lens of genomics
Abstract Histiocytic neoplasms are rare haematologic diseases characterised by clonal expansions of cells with a monocyte, macrophage or dendritic cell phenotype. Their clinical manifestations are diverse, ranging from indolent lesions to aggressive systemic disease.
Paul G Kemps +3 more
wiley +1 more source
Case Report: Presenting as optic neuritis-a biopsy-proven IgG4 anti-NF155-positive combined central and peripheral demyelination syndrome. [PDF]
Peng Y +6 more
europepmc +1 more source
Associations between TMEM106B C‐terminal fragment aggregation, age, and TDP‐43 or tau pathology
TMEM106B C‐terminal fragment (CTF) aggregation represents an age‐associated, common, diffuse phenomenon emerging after midlife with a weak association with TDP‐43 or tau pathology. These findings suggest that TMEM106B fibrillization may define a distinct axis of protein aggregation in the aging human brain. Abstract Transmembrane protein 106B (TMEM106B)
Albert Acewicz +5 more
wiley +1 more source
Osmotic Demyelination Syndrome and Pituitary Apoplexy Following mRNA COVID-19 Vaccination: A Case Report. [PDF]
Kopanos S +3 more
europepmc +1 more source
FIG4 is essential for lysosomal homeostasis. FIG4‐related disorders present as a continuous spectrum from the juvenile lethality in Yunis‐Varon syndrome to an increased risk of amyotrophic lateral sclerosis (ALS) in adult life. FIG4‐related disorders comprise a novel group of disorders of lysosomal homeostasis and can be classified into severe ...
Pankaj Prasun, Matthew Rasberry
wiley +1 more source
Editorial: Neuropathology of Autoimmune Inflammatory Demyelination Disorders
Manuel Zeitelhofer +3 more
doaj +1 more source
From insights to innovations: evaluating preclinical paradigms in demyelinating disease therapeutics. [PDF]
Karbalaee M +4 more
europepmc +1 more source
ABSTRACT The peripheral nervous system (PNS) is responsible for innervating all regions of the body outside of the central nervous system (CNS), the latter consisting of the brain, spinal cord, and optic nerves. While myelin is an essential component for the efficient functioning of both CNS and peripheral nerve cells, it is particularly important for ...
Kathleen Margaret Hagen +1 more
wiley +1 more source
Extensive Osmotic Demyelination Syndrome With a Concomitant Cytotoxic Lesion of the Corpus Callosum in Hyperemesis Gravidarum: A Case Report. [PDF]
Abouchiba S +9 more
europepmc +1 more source

