Results 141 to 150 of about 117,570 (300)

Clinical reasoning in feline non‐ambulatory tetraparesis or tetraplegia: Which combination of clinical information is useful?

Veterinary Record, EarlyView.
Abstract Background Non‐ambulatory tetraparesis or tetraplegia in cats may constitute a diagnostic challenge for general practitioners. Therefore, this study aimed to evaluate if clinical variables from signalment, history, clinical examination and basic ancillary tests are associated with underlying diagnoses in cats with non‐ambulatory tetraparesis ...
Guido Bertoldi, Steven De Decker
wiley   +1 more source

Audiological Characteristics in Vestibular Schwannoma Patients

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Vestibular schwannoma (VS) is a benign tumor that originates from the Schwann cells of the vestibular nerve sheath in the internal auditory canal. This retrospective study collected data from patients with VS who underwent surgical treatment to identify their demographic characteristics and audiometric features.
Shan Zeng, Yi‐Yun Lou, Hui‐Qian Yu, Wei‐Dong Zhao, Wen‐Yan Li   +4 more
wiley   +1 more source

Associations between TMEM106B C‐terminal fragment aggregation, age, and TDP‐43 or tau pathology

Brain Pathology, EarlyView.
TMEM106B C‐terminal fragment (CTF) aggregation represents an age‐associated, common, diffuse phenomenon emerging after midlife with a weak association with TDP‐43 or tau pathology. These findings suggest that TMEM106B fibrillization may define a distinct axis of protein aggregation in the aging human brain. Abstract Transmembrane protein 106B (TMEM106B)
Albert Acewicz, Sylwia Tarka, Michał Grzegorczyk, Radosław Rzepliński, Teresa Wierzba‐Bobrowicz, Tomasz Stępień   +5 more
wiley   +1 more source

LPC18:0 Secreted by Exogenous Neural Stem Cells Potentiates Neurogenesis and Functional Recovery via GPR55‐Mediated Signalling in Spinal Cord Injury

Cell Proliferation, EarlyView.
LPC18:0 secreted by exogenous neural stem cells potentiates neurogenesis via the GPR55/AKT/GSK3β signalling axis, which ultimately promotes spinal cord injury recovery. ABSTRACT Spinal cord injury (SCI) is a devastating condition with limited therapeutic options. Although neural stem cell (NSC) transplantation shows regenerative potential, its efficacy
Dong Chen, Shuo Liu, Le‐Yi Tu, Ming‐Mei Yang, Cong‐Wang Xu, Yue Jiang, Hui Yang, Chen‐Xu Tai, Yan‐Ning Wang, Yuan‐Yuan Xie, Ping‐Ping Shen, Bin Wang   +11 more
wiley   +1 more source

Optimising the Therapeutic Window: A Systematic Review and Network Meta‐Analysis of Pregabalin Dosing Strategies for Painful Diabetic Neuropathy

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Although pregabalin is a first‐line therapy for painful diabetic polyneuropathy (PDPN), its optimal dose–response relationship remains unclear. We conducted a network meta‐analysis to evaluate the efficacy and safety of fixed pregabalin dosages in PDPN patients.
Doyun Kwon, Hee‐Jae Jung, Junho Nam, Jonghae Kim, Eonju Jeon, Sanggyu Kwak   +5 more
wiley   +1 more source

Electroacupuncture and category IV LASER for treating suprascapular neuropathy in a two‐year‐old Arabian filly

Equine Veterinary Education, EarlyView.
Summary A 2‐year‐old Arabian filly presented with acute onset grade 4/5 (AAEP) right forelimb lameness and hindlimb ataxia following a collision with another horse and subsequent fall. The right forelimb lameness was associated with marked scapulohumeral joint instability.
O. E. Newman, B. Dunkel, M. Perrier
wiley   +1 more source

Proteolytic remodelling of the extracellular matrix by pericytes

The FEBS Journal, EarlyView.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard, Ella Milne, Kate Qian, Paola Campagnolo, Salvatore Santamaria   +4 more
wiley   +1 more source

Preservation of positive emotion recognition in patients with multiple sclerosis: Artefact related to methodological issues or real feature of the disorder?

Journal of Neuropsychology, EarlyView.
Abstract Prior studies in multiple sclerosis (MS) suggest preserved recognition of positive emotions despite deficits for negative ones, but this dissociation may reflect methodological limitations (valence‐asymmetry: positive‐valence being limited to happiness/joy in basic‐emotion sets). This study tested whether emotion–recognition deficits in MS are
Laurent Zikos, Antonio Pinti, Henrique Sequeira, Cécile Donze, Arnaud Kwiatkowski, Béatrice Degraeve, Bruno Lenne   +6 more
wiley   +1 more source

Teriflunomide Attenuates Demyelination and Enhances Remyelination in Organotypic Brain Slice Cultures Through Modulation of Glial Cell Dynamics. [PDF]

CNS Neurosci Ther
Kronenberg J, Schröder LJ, Reinsberg H, Skripuletz T, Heckers S, Hansmann F, Baumgärtner W, Stangel M, Gudi V.   +8 more
europepmc   +1 more source

Hypoadrenocorticism‐like syndrome in a cat with Tritrichomonas foetus infection: a case report

Journal of Small Animal Practice, EarlyView.
A reduced sodium: potassium ratio is an uncommon finding in cats, and is typically associated with conditions such as hypoadrenocorticism, severe renal and cardiovascular diseases, cavitary effusion and certain non‐parasitic gastrointestinal diseases.
M. Crisonà, F. Fracassi, A. M. Tardo, S. Okonji, F. Del Baldo   +4 more
wiley   +1 more source