Results 121 to 130 of about 94,021 (297)

Cuprizone-induced demyelination in Wistar rats; electrophysiological and histological assessment

, 2013
OBJECTIVES: Multiple Sclerosis (MS) is a disease that affects the Central Nervous System by destructing myelin shield and also can affects the peripheral nervous system.
Boylu, N. T., KÖSE, HAYRULLAH, Basoglu, HARUN   +2 more
core  

Finding My Path: Listening, Learning, and Leading in Rare Disease: The 2025 Hower Award

Annals of the Child Neurology Society, EarlyView.
Andrea Gropman
wiley   +1 more source

Multi‐Parametric Phase‐Cycled Balanced Steady‐State Free Precession Brain Tissue Characterization in Relapsing‐Remitting Multiple Sclerosis

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Time‐efficient phase‐cycled balanced steady‐state free precession (pc‐bSSFP) imaging is a novel microstructure‐ and myelin‐sensitive approach for multi‐parametric brain tissue characterization not yet evaluated in demyelinating diseases such as multiple sclerosis (MS).
Florian Birk, Benjamin Bender, Hamzeh Tesh, Anagha Deshmane, Maris M. Fabian, Markus C. Kowarik, Tobias Lindig, Ulrike Ernemann, Klaus Scheffler, Rahel Heule   +9 more
wiley   +1 more source

Hypoxic Neuroinflammation in the Pathogenesis of Multiple Sclerosis

Brain Sciences
Multiple sclerosis (MS) is an autoimmune disease that damages the myelin sheath around the central nervous system axons, leading to neurological dysfunction.
Bethany Y. A. Hollingworth, Patrick N. Pallier, Stuart I. Jenkins, Ruoli Chen   +3 more
doaj   +1 more source

Logistic Regression Model for Demyelination (ROC Curve: AUC = 0.635).

, 2015
Logistic Regression Model for Demyelination (ROC Curve: AUC = 0.635).
Karl L. Hussman (780216), Gabriela Marin (780217), David Han (432143), Kristina Dushaj (398826), Mona Li (633882), Rajendra D. Badgaiyan (338181), Richard Smayda (780218), Mark S. Gold (121308), Kenneth Blum (277781), Eric R. Braverman (277782)   +9 more
core   +1 more source

Vitamin B12 deficiency in an infant secondary to nutritional deficiency and an inadequate maternal diet

JPGN Reports, EarlyView.
ABSTRACT Vitamin B12 (cobalamin, Cbl) is an essential micronutrient for DNA synthesis and neurological development. Its deficiency in infants, although infrequent in developed countries, can cause megaloblastic anemia, psychomotor delay, and neurological damage that may become irreversible if not treated early.
Sandra Sala‐Lluch, Nerea Mesas‐Vila, Susana Ferrando‐Monleón, Ana Barrés‐Fernández, Cristina Villar‐Vera, José Vicente Arcos‐Machancoses   +5 more
wiley   +1 more source

INVESTIGATING A TECHNOLOGY TO RESTORE SIGNAL TRANSMISSION ACROSS DEMYELINATED AXONS IN MULTIPLE SCLEROSIS: A COMPREHENSIVE REVIEW

Автоматизация технологических и бизнес-процессов
. Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by the degradation of myelin, a critical component of axons in the central nervous system (CNS).
Chathurika AGJ, Hettige B, Marikar FMMT
doaj   +1 more source

Longest survivor of pulmonary atresia with ventricular septal defect without surgical intervention

ESC Heart Failure, Volume 12, Issue 2, Page 1499-1507, April 2025.
Sang Zhou, Yu Wu, Guoran Li, Yongwen Qin, Man Qi, Zhitao Jin   +5 more
wiley   +1 more source

Efficacy of Ultrasound‐Guided Intercostal Nerve Block With Liposomal Bupivacaine for Treating Postherpetic Neuralgia in Adult Patients

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The study aimed to investigate the efficacy of ultrasound‐guided intercostal nerve block (ICNB) with liposomal bupivacaine (LB) comparing ropivacaine‐dexamethasone (RD) for treating postherpetic neuralgia (PHN) in adult patients. A total of 108 patients were randomized 1:1 to receive ICNB with LB or ICNB with RD.
Jin Li, Xiang‐Yu Fang
wiley   +1 more source

Betaine Attenuates Cuprizone-Induced Cortical Demyelination: The Role of the WNT4/mTOR Signalling Pathway in Regulating Astrogliosis and Synaptic Integrity. [PDF]

J Biochem Mol Toxicol
Betaine helps to restore the dysfunctional communication between oxidative stress and inflammation, and it also improves demyelination in cuprizone‐induced demyelinating disease within the cerebral cortex. ABSTRACT Cortical grey matter pathology manifests early demyelinating diseases and is a primary driver of permanent neurological impairment.
Said YM, Abd Elkader HAE, Bekheet GJ, Abdel Salam S, Essawy AE.   +4 more
europepmc   +2 more sources