Results 131 to 140 of about 94,021 (297)

A Data‐Driven Threshold for Extreme Hyponatremia in the Emergency Department and Its Association With 28‐Day Mortality

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Hyponatremia is a common electrolyte disorder in the emergency department (ED), but its clinical burden is not evenly distributed across the sodium spectrum. We conducted a retrospective observational cohort study of adult ED encounters at a tertiary referral hospital between July 2019 and July 2024 to identify a data‐driven threshold for ...
Yalcin Golcuk, Ömer‐Faruk Karakoyun, Fulden Cantaş‐Türkiş, İsmail Kırlı, Satuk‐Buğra Yıldırım, Bekir Baran, Burcu Kaymak‐Golcuk   +6 more
wiley   +1 more source

Exteroceptive Reflexes in Stiff Person Syndrome, Other Neurological Conditions and Healthy Controls

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Stiff person syndrome (SPS) is a rare disabling neurological condition with overlapping symptomatology with more common neurological conditions. Exaggerated exteroceptive reflex mechanisms are thought to play a role in its pathophysiology.
Belinda Cruse, Duncan Wilson, Hugo Morales Briceno, Pamela Garcia, Victor Zhang, Jessica Qiu, Tomas Kalincik, Neil Mahant, Victor Shue Chung Fung   +8 more
wiley   +1 more source

COVID‐19 Amplifies Sex‐Specific Dopamine and Glial Responses in a Parkinson's Disease Mouse Model

Movement Disorders, EarlyView.
Abstract Background Exposure to environmental agents, including viral infections, may increase Parkinson's disease (PD) susceptibility, especially in males, but the neurodegenerative risk extent of COVID‐19 remains uncertain. Objectives We investigated the plausible link between severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and
Ifeoluwa Awogbindin, Mélanie Bourque, Marc Morissette, Marie‐Ève Hamelin, Chantal Rhéaume, Jared VanderZwaag, Antonia Landwehr, Disha Patel, Guy Boivin, Marie‐Ève Tremblay, Thérèse Di Paolo   +10 more
wiley   +1 more source

Structural Brain and Spinal Cord Signature of Spinocerebellar Ataxia 27B: A Multisite MRI‐Based Study

Movement Disorders, EarlyView.
Abstract Background SCA27B is a recently described ataxia, the precise anatomical basis of which remains unclear. Objective The goal was to characterize the structural brain and spinal cord magnetic resonance imaging (MRI) signature of spinocerebellar ataxia 27B (SCA27B) using multimodal quantitative imaging.
Nadson Bruno Serra Santos, Camila Caroso Lobo, Thiago Junqueira Ribeiro Rezende, Alberto Rolim Muro Martinez, Luiza A. Corazza, Luiz Eduardo Novis, Orlando Graziani Povoas Barsottini, José Luiz Pedroso, Pedro José Tomaselli, Wilson Marques Jr, Antônio Carlos dos Santos, David Pellerin, Bernard Brais, Roberta La Piana, Jemimah Harding, Penny Snell, Paul J. Lockhart, David Szmulewicz, Ian H. Harding, Marcondes Cavalcante França Jr   +19 more
wiley   +1 more source

A Rapid T1‐Independent Sequence for Cerebrospinal Fluid Water Standard Correction: Application to Improved Proton Density Mapping in Brain

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To improve brain water content measures relative to cerebrospinal fluid (CSF) by including a rapid T1‐independent sequence to correct for CSF T1 errors. Methods Proton density (PD) was estimated from a 3D multiple echo gradient echo sequence by extrapolating to TE = 0 and then correcting for T1 losses using a T1 map from 3D MP2RAGE. To
Kiarash Jalali, Nashwan Naji, Peter Seres, Alan H. Wilman   +3 more
wiley   +1 more source

MICROBIAL AGENTS AS TRIGGERS OF MULTIPLE SCLEROSIS DEVELOPMENT

Инфекция и иммунитет, 2019
Multiple sclerosis (MS) is currently an urgent medical and social problem. This is due to the high prevalence of this pathology among neurological diseases with the predominant lesion of young people and subsequent rapid disability.
Yu. Froltsova, A. Lapshtaeva, T. Evseeva, Y. Kostina   +3 more
doaj  

Glial Cell Dynamics in Neuroinflammation: Mechanisms, Interactions, and Therapeutic Implications

Biomedicines
Neuroinflammation is a defining feature of many neurological disorders, including neurodegenerative diseases, traumatic brain injury, and demyelinating conditions.
Mario García-Domínguez
doaj   +1 more source

PO132 Clinical features of demyelination following anti-tnfΑ therapy

, 2017
PO132 Clinical features of demyelination following anti-tnfΑ ...
Tariq Ahmad (198659), Jeremy Hobart (6035753), Alexander Spiers (18618361), Roswell Martin (19227871), Alasdair Coles (3150720), Peter Hendy (18617845), James Goodhand (19177957), Neel Heerasing (13087041), Gareth Walker (7163093), Tim Harrower (13422564)   +9 more
core  

Predicting Mesoscopic Larmor Frequency Shifts in Ex Vivo Porcine Optic Nerve

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Larmor frequency shifts in white matter (WM) vary with fiber orientation due to anisotropic microstructure. Since clinical voxels are significantly larger than these microscopic frequency variations, the measured signal represents a bulk average of local shifts.
Anders Dyhr Sandgaard, André Pampel, Roland Müller, Niklas Wallstein, Toralf Mildner, Carsten Jäger, Markus Morawski, Aage Kristian Olsen Alstrup, Harald E. Möller, Sune Nørhøj Jespersen   +9 more
wiley   +1 more source

Electrical Modalities in the Rehabilitation of Peripheral Nerve Injuries: State of the Literature and Current Clinical Applications

Muscle &Nerve, EarlyView.
ABSTRACT Peripheral nerve injuries (PNIs) are a common cause of long‐term motor and sensory disability despite advances in microsurgical repair. Functional recovery following PNI depends not only on axonal regeneration, but also on preservation of distal nerve pathways, maintenance of neuromuscular junction integrity, prevention of irreversible muscle ...
Sarah M. Smith, Kirsten M. Schlosser, Ranee Munaim, Stephanie H. Vu, JulieAnn H. Uh, Yusha K. Liu   +5 more
wiley   +1 more source